Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Roland Koslowski"'
Autor:
Heinz Fehrenbach, Christian F. Poets, Katharina Schaal, Roland Koslowski, Wolfgang Bernhard, Erwin Schleicher, Marco Raith
Publikováno v:
Journal of Applied Physiology. 112:1317-1328
Respiratory distress and bronchopulmonary dysplasia (BPD) are major problems in preterm infants that are often addressed by glucocorticoid treatment and increased oxygen supply, causing catabolic and injurious side effects. Recombinant human keratino
Autor:
Gerold Barth, Robert Bläsche, Marcus Gentsch, Kathrin Barth, Roland Koslowski, A. Pfüller, Michael Kasper, I. Parshyna
Publikováno v:
Histochemistry and Cell Biology. 123:239-247
Using the new alveolar epithelial type I-like cell line R3/1 derived from fetal rat lung, we studied the distribution of connexin43 and caveolin-1 under conditions of bleomycin-induced injury in vitro. We show that under normal as well as under condi
Publikováno v:
Experimental and Toxicologic Pathology. 55:497-503
To investigate the pathomechanisms of bleomycin-induced early inflammation of lung parenchyma which is known to result in pulmonary fibrosis, we examined the in vitro effect of bleomycin (BLM) on primary human pulmonary microvascular endothelial cell
Publikováno v:
European Respiratory Journal. 22:427-435
Endogenous inhibitors tightly control the activity of proteinases in the extracellular space. Proteinase/antiproteinase imbalance may be caused by predominance of proteinases, resulting in severe tissue damage or abundance of proteinase inhibitors, l
Publikováno v:
Experimental and Toxicologic Pathology. 55:257-264
Lung fibrosis is the end-point of numerous lung disorders induced by a pneumonia or by a variety of different noxes, one of which is the cytostatic drug bleomycin (BLM). Fibrosis is characterized by excessive extracellular matrix accumulation. Macrop
Publikováno v:
Clinical & Experimental Allergy. 32:1251-1258
Summary Background Structural remodelling of airways in asthma that follows inflammation may be affected by surfactant protein D (SP-D)-mediated effects on the immune response. Objective To determine potential sites of SP-D interaction with the pulmo
Publikováno v:
European Respiratory Journal. 18:347-356
Several lines of evidence support the hypothesis of the involvement of altered proteoglycan deposition in the development of lung diseases. UDP-d-xylose: core protein β-d-xylosyltransferase (UDP-xylosyltransferase; EC 2.4.2.26) is a key enzyme for t
Autor:
Robert J. Mason, Tianli Pan, Heinz Fehrenbach, Martin Müller, D Schuh, Roland Koslowski, Michael Kasper
Publikováno v:
Histochemistry and Cell Biology. 114:49-61
Keratinocyte growth factor (KGF) induces rapid and transient hyperplasia of alveolar epithelial type II cells. We sought to determine components of the apoptotic process involved in the resolution of this hyperplasia and the fate of the apoptotic cel
Publikováno v:
Clinica Chimica Acta. 271:45-56
Changes in the activities of several proteinases and their inhibitors were investigated during the development of bleomycin-induced pulmonary fibrosis in rat. Studies on the proteinase-antiproteinase-ratio may contribute to the understanding of the m
Publikováno v:
Histochemistry and Cell Biology. 104:397-405
ICAM-1 is an intercellular adhesion molecule of the immunoglobulin supergene family involved in adherence of leukocytes to the endothelium and in leukocytic accumulation in pulmonary injury. In the current study, the antigen retrieval technique was u