Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Roland Kellner"'
Autor:
Manasi Gaikwad, Florian Richter, Rabea Götz, Aline Dörrbaum, Lena Schumacher, Jason Tonillo, Christian Frech, Roland Kellner, Carsten Hopf
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1418 (2023)
Studies of structural changes in mAbs under forced stress and storage conditions are essential for the recognition of degradation hotspots, which can be further remodeled to improve the stability of the respective protein. Herein, we used diethyl pyr
Externí odkaz:
https://doaj.org/article/0daf1a485f8e4053b1fd4f3c7305886e
Autor:
Anna Kaempffe, Elisa Bertotti, Federico Riccardi Sirtori, Doreen Könning, Nicolas Rasche, Roland Kellner, Stefan Hecht, Stephan Dickgiesser, Jan Anderl, Ilse De Salve, Harald Kolmar, Andrea Paoletti, Christian Schröter
Publikováno v:
Journal of pharmaceutical sciences. 110(12)
Appropriate selection of conjugation sites and conjugation technologies is now widely accepted as crucial for the success of antibody-drug conjugates (ADCs). Herein, we present ADCs conjugated by different conjugation methods to different conjugation
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2033
Antibody-drug conjugates (ADCs) have been proven to be a successful therapeutic concept, allowing targeted delivery of highly potent active pharmaceutical ingredients (HPAPIs) selectively to tumor tissue. So far, HPAPIs have been mainly attached to t
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2012
Antibody-drug conjugates (ADCs) are a relatively young class of cancer therapeutics that combine the superior selectivity of monoclonal antibodies (mAbs) with the high potency of cytotoxic agents. In the first generation of ADCs, the toxic payload is
Publikováno v:
Methods in Molecular Biology ISBN: 9781493996537
Antibody-drug conjugates (ADCs) have been proven to be a successful therapeutic concept, allowing targeted delivery of highly potent active pharmaceutical ingredients (HPAPIs) selectively to tumor tissue. So far, HPAPIs have been mainly attached to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::629f2609937d870a992527ccab5cf0ce
https://doi.org/10.1007/978-1-4939-9654-4_1
https://doi.org/10.1007/978-1-4939-9654-4_1
Publikováno v:
Methods in Molecular Biology ISBN: 9781493995455
Antibody-drug conjugates (ADCs) are a relatively young class of cancer therapeutics that combine the superior selectivity of monoclonal antibodies (mAbs) with the high potency of cytotoxic agents. In the first generation of ADCs, the toxic payload is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::598da8ed187868efb32cb6bb1372bb68
https://doi.org/10.1007/978-1-4939-9546-2_8
https://doi.org/10.1007/978-1-4939-9546-2_8
Autor:
Peter Nollau, Friedrich Lottspeich, Jens Hansen, Attila Tárnok, Christoph Wagener, Marius Ueffing, Edmund Maser, Wolfgang Mutter, Roland Kellner, Hannes Stockinger, Charalampos Aslanidis, Oswald Wagner, Andreas Radbruch, Andreas O. H. Gerstner, Dennis Hochstrasser, Fredrik Pontén, Knut Reinert, Stefan Müllner, Rolf Apweiler, Joachim Thiery, Hans G. Nothwang, Markus Kubicek, Helmut E. Meyer, Michael J. Taussig, Joël Vandekerckhove, Michael Neumaier, Hans-Werner Mewes, Andreas Thiel, G. Valet, Thomas Deufel, Gregor Rothe, Gerd Schmitz
Publikováno v:
Cytometry Part A
Cytometry Part A; Vol 75A
Cytometry Part A; Vol 75A
Recent developments in proteomics technology offer new opportunities for clinical applications in hospital or specialized laboratories including the identification of novel biomarkers, monitoring of disease, detecting adverse effects of drugs, and en
Publikováno v:
Physiological Entomology. 34:136-143
The adipokinetic hormone (AKH) of the large milkweed bug Oncopeltus fasciatus is isolated from an acidified methanolic extract of 200 corpora cardiaca, purified by single step reversed phase high-performance liquid chromatography (HPLC) and N-termina
Autor:
Friedrich Lottspeich, Barbara Seliger, Christian V. Recktenwald, Rudolf Lichtenfels, Derek Atkins, Roland Kellner, Ena Wang, Sven P. Dressler, Francesco M. Marincola, Maja Baumgärtner
Publikováno v:
PROTEOMICS. 9:1567-1581
Results obtained from expression profilings of renal cell carcinoma using different "ome"-based approaches and comprehensive data analysis demonstrated that proteome-based technologies and cDNA microarray analyses complement each other during the dis
Autor:
Gerd Gäde, Claudia Elisabeth Munte, Werner Kremer, Hans Robert Kalbitzer, Barbara Domogalla, Roland Kellner
Publikováno v:
FEBS Journal. 275:1163-1173
The hypertrehalosaemic hormone from the stick insect Carausius morosus (Cam-HrTH) contains a hexose covalently bound to the ring of the tryptophan, which is in the eighth position in the molecule. We show by solution NMR spectroscopy that the tryptop