Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Roland J Bainton"'
Autor:
Michael K DeSalvo, Samantha J Hindle, Zeid M Rusan, Souvinh eOrng, Kyle eHalliwill, Mark eEddison, Roland J Bainton
Publikováno v:
Frontiers in Neuroscience, Vol 8 (2014)
AbstractCentral nervous system (CNS) function is dependent on the stringent regulation of metabolites, drugs, cells, and pathogens exposed to the CNS space. Cellular blood-brain barrier (BBB) structures are highly specific checkpoints governing entry
Externí odkaz:
https://doaj.org/article/a41facb4eeeb4949aee45637670e64f7
Autor:
George A Lemieux, Michael J Keiser, Maria F Sassano, Christian Laggner, Fahima Mayer, Roland J Bainton, Zena Werb, Bryan L Roth, Brian K Shoichet, Kaveh Ashrafi
Publikováno v:
PLoS Biology, Vol 11, Iss 11, p e1001712 (2013)
Phenotypic screens can identify molecules that are at once penetrant and active on the integrated circuitry of a whole cell or organism. These advantages are offset by the need to identify the targets underlying the phenotypes. Additionally, logistic
Externí odkaz:
https://doaj.org/article/a529489b96fa4fc5afd289a55fbf78cf
Autor:
Eric C Kong, Katherine Woo, Haiyan Li, Tim Lebestky, Nasima Mayer, Melissa R Sniffen, Ulrike Heberlein, Roland J Bainton, Jay Hirsh, Fred W Wolf
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e9954 (2010)
Dopamine is a mediator of the stimulant properties of drugs of abuse, including ethanol, in mammals and in the fruit fly Drosophila. The neural substrates for the stimulant actions of ethanol in flies are not known. We show that a subset of dopamine
Externí odkaz:
https://doaj.org/article/066104f738704f84a55f0858b57064bc
Publikováno v:
PLoS Biology, Vol 2, Iss 12, p e408 (2004)
Drosophila has been developed recently as a model system to investigate the molecular and neural mechanisms underlying responses to drugs of abuse. Genetic screens for mutants with altered drug-induced behaviors thus provide an unbiased approach to d
Externí odkaz:
https://doaj.org/article/406cfa8270b7419fb9c84c6868638648
Publikováno v:
PLoS Biology, Vol 1, Iss 3, p E80 (2003)
In most organisms, germ cells are formed distant from the somatic part of the gonad and thus have to migrate along and through a variety of tissues to reach the gonad. Transepithelial migration through the posterior midgut (PMG) is the first active s
Externí odkaz:
https://doaj.org/article/011cfb941a13403ba1f660917ff9a593
Autor:
Jérémie Joffre, Lauren Rodriguez, Zachary A. Matthay, Elliot Lloyd, Alexander T. Fields, Roland J. Bainton, Philip Kurien, Anita Sil, Carolyn S. Calfee, Prescott G. Woodruff, David J. Erle, Carolyn Hendrickson, Matthew F. Krummel, Charles R. Langelier, Michael A. Matthay, Lucy Z. Kornblith, Judith Hellman, Sharvari Bhide, Sidney A. Carrillo, Suzanna Chak, Gabriela K. Fragiadakis, Rajani Ghale, Jeremy Giberson, Pat Glenn, Ana Gonzalez, Alejandra Jauregui, Norman Jones, Kirsten Kangelaris, Serena Ke, Tasha Lea, Deanna Lee, Aleskandra Lelidowicz, Raphael Lota, Michael Matthay, Jeff Milush, Viet Nguyen, Ahmad Sadeed Rashid, Nicklaus Rodriguez, Austin Sigman, Kevin Tang, Luz Torres Altamirano, Alyssa Ward, Andrew Willmore, Michael Wilson, Biniam Ambachew, Sarah Cary, Lauren Chalwell, Christopher Colwell, Chayse Jones, Clayton Josephy, Matthieu LeGrand, Juan Carlos Montoy, Aaron E. Kornblith, Brenda Nunez-Garcia, John J. Park, Arun Prakash, Brittany Robinson, India Shelley, Katherine D. Wick
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 206:961-972
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07733b6366ff177b5e2dcc5a836abd86
https://doi.org/10.1164/rccm.202107-1774oc
https://doi.org/10.1164/rccm.202107-1774oc
Autor:
Samantha J. Hindle, Roeben N. Munji, Elena Dolghih, Garrett Gaskins, Souvinh Orng, Hiroshi Ishimoto, Allison Soung, Michael DeSalvo, Toshihiro Kitamoto, Michael J. Keiser, Matthew P. Jacobson, Richard Daneman, Roland J. Bainton
Publikováno v:
Cell Reports, Vol 21, Iss 5, Pp 1304-1316 (2017)
Summary: Central nervous system (CNS) chemical protection depends upon discrete control of small-molecule access by the blood-brain barrier (BBB). Curiously, some drugs cause CNS side-effects despite negligible transit past the BBB. To investigate th
Externí odkaz:
https://doaj.org/article/ab536355a3d44a6c8f5909e9d8116224
Autor:
Alexander T. Fields, Rachael A. Callcut, Lucy Z. Kornblith, Zachary A. Matthay, Brenda Nunez-Garcia, Roland J. Bainton, Ellicott C. Matthay
Publikováno v:
Shock (Augusta, Ga.), vol 55, iss 2
Shock
Shock
BackgroundAltered postinjury platelet behavior is recognized in the pathophysiology of trauma-induced coagulopathy (TIC), but the mechanisms remain largely undefined. Studies suggest that soluble factors released by injury may inhibit signaling pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671b2faff8005f288c9d8046f931e04b
https://doi.org/10.1097/shk.0000000000001622
https://doi.org/10.1097/shk.0000000000001622
Autor:
Alexander T. Fields, Nasima Mayer, Lucy Z. Kornblith, Joseph Cuschieri, Yale A. Santos, Zachary A. Matthay, Rachael A. Callcut, Kord M. Kober, Man-Cheung Lee, Cedric M.V. Bainton, Roland J. Bainton, Fahima Mayer
Publikováno v:
The Journal of Trauma and Acute Care Surgery
The journal of trauma and acute care surgery, vol 92, iss 2
The journal of trauma and acute care surgery, vol 92, iss 2
Supplemental digital content is available in the text.
BACKGROUND The earliest measurable changes to postinjury platelet biology may be in the platelet transcriptome, as platelets are known to carry messenger ribonucleic acids (RNAs), and there
BACKGROUND The earliest measurable changes to postinjury platelet biology may be in the platelet transcriptome, as platelets are known to carry messenger ribonucleic acids (RNAs), and there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2103a1468e7a315386e67d324eaf1838
https://pubmed.ncbi.nlm.nih.gov/34738997
https://pubmed.ncbi.nlm.nih.gov/34738997
Autor:
Arun Prakash, Juan Carlos C. Montoy, Ryan Sincic, Roland J. Bainton, Steven Straube, Jeanne Noble, Philip A. Kurien, Won Lee, Aaron E. Kornblith, Ralph C. Wang
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
IntroductionThe ongoing SARS-CoV-2 pandemic has spurred the development of numerous point of care (PoC) immunoassays. Assessments of performance of available kits are necessary to determine their clinical utility. Previous studies have mostly perform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3db3300f57cae51689a83c663444976
http://europepmc.org/articles/PMC7724668
http://europepmc.org/articles/PMC7724668