Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Roland J Bainton"'
Autor:
Zachary A. Matthay, Alexander T. Fields, Katherine D. Wick, Chayse Jones, H. Clifford Lane, Kimberly Herrera, Brenda Nuñez-Garcia, Efstathios Gennatas, Carolyn M. Hendrickson, Aaron E. Kornblith, Michael A. Matthay, Lucy Z. Kornblith, the COVID-19 Associated Coagulopathy Inflammation Thrombosis (Co-ACIT) Study Group, Biniam Ambachew, Roland J. Bainton, Sarah Cary, Lauren Chalwell, Christopher Colwell, Clayton Josephy, Philip Kurien, Deanna Lee, Matthieu LeGrand, Juan Carlos Montoy, Viet Nguyen, John J. Park, Arun Prakash, Brittany Robinson, Shelley India
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThere remains a need to better identify patients at highest risk for developing severe Coronavirus Disease 2019 (COVID-19) as additional waves of the pandemic continue to impact hospital systems. We sought to characterize the association
Externí odkaz:
https://doaj.org/article/5d4cf09f756c492f92513041a74158f6
Autor:
Alexander T. Fields, Elizabeth A. Andraska, Christof Kaltenmeier, Zachary A. Matthay, Kimberly Herrera, Brenda Nuñez-Garcia, Chayse M. Jones, Katherine D. Wick, Silvia Liu, Jian-Hua Luo, Yan-Ping Yu, Michael A. Matthay, Carolyn M. Hendrickson, Roland J. Bainton, Tessa J. Barrett, Jeffrey S. Berger, Matthew D. Neal, Lucy Z. Kornblith, the COVID-19 Associated Coagulopathy Inflammation and Thrombosis (Co-ACIT) Study Group, Biniam Ambachew;, Sarah Cary;, Lauren Chalwell;, Christopher Colwell;, Clayton Josephy;, Deanna Lee;, Matthieu LeGrand;, Juan Carlos Montoy;, Aaron E. Kornblith;, Philip Kurien;, Brenda Nunez-Garcia;, Viet Nguyen;, John J. Park;, Arun Prakash;, Brittany Robinson;, India Shelley
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThromboinflammatory complications are well described sequalae of Coronavirus Disease 2019 (COVID-19), and there is evidence of both hyperreactive platelet and inflammatory neutrophil biology that contributes to the thromoinflammatory mili
Externí odkaz:
https://doaj.org/article/f9d1e7968ae74e3c854e8e76aeab2cc3
Autor:
Jérémie Joffre, Lauren Rodriguez, Zachary A. Matthay, Elliot Lloyd, Alexander T. Fields, Roland J. Bainton, Philip Kurien, Anita Sil, Carolyn S. Calfee, Prescott G. Woodruff, David J. Erle, Carolyn Hendrickson, Matthew F. Krummel, Charles R. Langelier, Michael A. Matthay, Lucy Z. Kornblith, Judith Hellman, Sharvari Bhide, Sidney A. Carrillo, Suzanna Chak, Gabriela K. Fragiadakis, Rajani Ghale, Jeremy Giberson, Pat Glenn, Ana Gonzalez, Alejandra Jauregui, Norman Jones, Kirsten Kangelaris, Serena Ke, Tasha Lea, Deanna Lee, Aleskandra Lelidowicz, Raphael Lota, Michael Matthay, Jeff Milush, Viet Nguyen, Ahmad Sadeed Rashid, Nicklaus Rodriguez, Austin Sigman, Kevin Tang, Luz Torres Altamirano, Alyssa Ward, Andrew Willmore, Michael Wilson, Biniam Ambachew, Sarah Cary, Lauren Chalwell, Christopher Colwell, Chayse Jones, Clayton Josephy, Matthieu LeGrand, Juan Carlos Montoy, Aaron E. Kornblith, Brenda Nunez-Garcia, John J. Park, Arun Prakash, Brittany Robinson, India Shelley, Katherine D. Wick
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 206:961-972
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07733b6366ff177b5e2dcc5a836abd86
https://doi.org/10.1164/rccm.202107-1774oc
https://doi.org/10.1164/rccm.202107-1774oc
Autor:
Samantha J. Hindle, Roeben N. Munji, Elena Dolghih, Garrett Gaskins, Souvinh Orng, Hiroshi Ishimoto, Allison Soung, Michael DeSalvo, Toshihiro Kitamoto, Michael J. Keiser, Matthew P. Jacobson, Richard Daneman, Roland J. Bainton
Publikováno v:
Cell Reports, Vol 21, Iss 5, Pp 1304-1316 (2017)
Summary: Central nervous system (CNS) chemical protection depends upon discrete control of small-molecule access by the blood-brain barrier (BBB). Curiously, some drugs cause CNS side-effects despite negligible transit past the BBB. To investigate th
Externí odkaz:
https://doaj.org/article/ab536355a3d44a6c8f5909e9d8116224
Autor:
Alexander T. Fields, Rachael A. Callcut, Lucy Z. Kornblith, Zachary A. Matthay, Brenda Nunez-Garcia, Roland J. Bainton, Ellicott C. Matthay
Publikováno v:
Shock (Augusta, Ga.), vol 55, iss 2
Shock
Shock
BackgroundAltered postinjury platelet behavior is recognized in the pathophysiology of trauma-induced coagulopathy (TIC), but the mechanisms remain largely undefined. Studies suggest that soluble factors released by injury may inhibit signaling pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671b2faff8005f288c9d8046f931e04b
https://doi.org/10.1097/shk.0000000000001622
https://doi.org/10.1097/shk.0000000000001622
Autor:
Alexander T. Fields, Nasima Mayer, Lucy Z. Kornblith, Joseph Cuschieri, Yale A. Santos, Zachary A. Matthay, Rachael A. Callcut, Kord M. Kober, Man-Cheung Lee, Cedric M.V. Bainton, Roland J. Bainton, Fahima Mayer
Publikováno v:
The Journal of Trauma and Acute Care Surgery
The journal of trauma and acute care surgery, vol 92, iss 2
The journal of trauma and acute care surgery, vol 92, iss 2
Supplemental digital content is available in the text.
BACKGROUND The earliest measurable changes to postinjury platelet biology may be in the platelet transcriptome, as platelets are known to carry messenger ribonucleic acids (RNAs), and there
BACKGROUND The earliest measurable changes to postinjury platelet biology may be in the platelet transcriptome, as platelets are known to carry messenger ribonucleic acids (RNAs), and there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2103a1468e7a315386e67d324eaf1838
https://pubmed.ncbi.nlm.nih.gov/34738997
https://pubmed.ncbi.nlm.nih.gov/34738997
Autor:
Michael K DeSalvo, Samantha J Hindle, Zeid M Rusan, Souvinh eOrng, Kyle eHalliwill, Mark eEddison, Roland J Bainton
Publikováno v:
Frontiers in Neuroscience, Vol 8 (2014)
AbstractCentral nervous system (CNS) function is dependent on the stringent regulation of metabolites, drugs, cells, and pathogens exposed to the CNS space. Cellular blood-brain barrier (BBB) structures are highly specific checkpoints governing entry
Externí odkaz:
https://doaj.org/article/a41facb4eeeb4949aee45637670e64f7
Autor:
Arun Prakash, Juan Carlos C. Montoy, Ryan Sincic, Roland J. Bainton, Steven Straube, Jeanne Noble, Philip A. Kurien, Won Lee, Aaron E. Kornblith, Ralph C. Wang
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
IntroductionThe ongoing SARS-CoV-2 pandemic has spurred the development of numerous point of care (PoC) immunoassays. Assessments of performance of available kits are necessary to determine their clinical utility. Previous studies have mostly perform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3db3300f57cae51689a83c663444976
http://europepmc.org/articles/PMC7724668
http://europepmc.org/articles/PMC7724668
Autor:
George A Lemieux, Michael J Keiser, Maria F Sassano, Christian Laggner, Fahima Mayer, Roland J Bainton, Zena Werb, Bryan L Roth, Brian K Shoichet, Kaveh Ashrafi
Publikováno v:
PLoS Biology, Vol 11, Iss 11, p e1001712 (2013)
Phenotypic screens can identify molecules that are at once penetrant and active on the integrated circuitry of a whole cell or organism. These advantages are offset by the need to identify the targets underlying the phenotypes. Additionally, logistic
Externí odkaz:
https://doaj.org/article/a529489b96fa4fc5afd289a55fbf78cf
Multicellular organisms employ concurrent gene regulatory programs to control development and physiology of cells and tissues. The Drosophila melanogaster model system has a remarkable history of revealing the genes and mechanisms underlying fundamen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa05835891f5e758ab6588d3ab46985
