Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Roland J, Pieters"'
Autor:
Janja Sluga, Tihomir Tomašič, Marko Anderluh, Martina Hrast Rambaher, Gregor Bajc, Alen Sevšek, Nathaniel I. Martin, Roland J. Pieters, Marjana Novič, Katja Venko
Publikováno v:
Antibiotics, Vol 13, Iss 8, p 751 (2024)
Bacteria are capable of remarkable adaptations to their environment, including undesirable bacterial resistance to antibacterial agents. One of the most serious cases is an infection caused by multidrug-resistant Staphylococcus aureus, which has unfo
Externí odkaz:
https://doaj.org/article/a64f174040894b3aa54b7e163275ddbd
Autor:
Maria Eleni Mavrogeni, Mostafa Asadpoor, Jo H. Judernatz, Ingrid van Ark, Marc M. S. M. Wösten, Karin Strijbis, Roland J. Pieters, Gert Folkerts, Saskia Braber
Publikováno v:
Toxins, Vol 15, Iss 10, p 586 (2023)
Clostridioides difficile infection is expected to become the most common healthcare-associated infection worldwide. C. difficile-induced pathogenicity is significantly attributed to its enterotoxin, TcdA, which primarily targets Rho-GTPases involved
Externí odkaz:
https://doaj.org/article/5b11f8c5a56e4b7d8753ec04e12aaf61
Autor:
Dania Martínez-Alarcón, Viviane Balloy, Jean-Philippe Bouchara, Roland J. Pieters, Annabelle Varrot
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Scedosporium apiospermum is an emerging opportunistic fungal pathogen responsible for life-threatening infections in humans. Host–pathogen interactions often implicate lectins that have become therapeutic targets for the development of car
Externí odkaz:
https://doaj.org/article/eeac914cf9ca4ecdaad1df82d0cf84b1
Autor:
Yang Xu, Víctor M. Hernández-Rocamora, Joseph H. Lorent, Ruud Cox, Xiaoqi Wang, Xue Bao, Marjon Stel, Gaël Vos, Ramon M. van den Bos, Roland J. Pieters, Joe Gray, Waldemar Vollmer, Eefjan Breukink
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104753- (2022)
Summary: N-Acetylglucosamine (GlcNAc) is an essential monosaccharide required in almost all organisms. Fluorescent labeling of the peptidoglycan (PG) on N-acetylglucosamine has been poorly explored. Here, we report on the labeling of the PG with a bi
Externí odkaz:
https://doaj.org/article/0367056e977e4ab283b044661202a3d2
Publikováno v:
Vaccines, Vol 11, Iss 2, p 219 (2023)
Glycoconjugate vaccines have proven their worth in the protection and prevention of infectious diseases. The introduction of the Haemophilus influenzae type b vaccine is the prime example, followed by other glycoconjugate vaccines. Glycoconjugate vac
Externí odkaz:
https://doaj.org/article/dad35c9622934e30b0186b32adac5da8
Autor:
Reshmi Mukherjee, Victor J. Somovilla, Fabrizio Chiodo, Sven Bruijns, Roland J. Pieters, Johan Garssen, Yvette van Kooyk, Aletta D. Kraneveld, Jeroen van Bergenhenegouwen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14745 (2022)
Human milk oligosaccharides (HMOs) and their most abundant component, 2′-Fucosyllactose (2′-FL), are known to be immunomodulatory. Previously, it was shown that HMOs and 2′-FL bind to the C-type lectin receptor DC-SIGN. Here we show, using a li
Externí odkaz:
https://doaj.org/article/5e6c25f874b1419e8b6d767dcf6ce385
Autor:
Mostafa Asadpoor, Georgia-Nefeli Ithakisiou, Jos P. M. van Putten, Roland J. Pieters, Gert Folkerts, Saskia Braber
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The bacterial pathogens Streptococcus agalactiae (GBS) and Staphylococcus aureus (S. aureus) cause serious infections in humans and animals. The emergence of antibiotic-resistant isolates and bacterial biofilm formation entails the urge of novel trea
Externí odkaz:
https://doaj.org/article/c0cc2f93ed0d497c8f37e421c8543636
Autor:
Ilhan Tomris, Luca Unione, Linh Nguyen, Pouya Zaree, Kim M. Bouwman, Lin Liu, Zeshi Li, Jelle A. Fok, María Ríos Carrasco, Roosmarijn van der Woude, Anne L. M. Kimpel, Mirte W. Linthorst, Sinan E. Kilavuzoglu, Enrico C. J. M. Verpalen, Tom G. Caniels, Rogier W. Sanders, Balthasar A. Heesters, Roland J. Pieters, Jesús Jiménez-Barbero, John S. Klassen, Geert-Jan Boons, Robert P. de Vries
Publikováno v:
ACS chemical biology. American Chemical Society
SARS-CoV-2 viruses engage ACE2 as a functional receptor with their spike protein. The S1 domain of the spike protein contains a C-terminal receptor binding domain (RBD) and an N-terminal domain (NTD). The NTD of other coronaviruses includes a glycan
Autor:
Matjaž Weiss, Elena M. Loi, Maša Sterle, Cyril Balsollier, Tihomir Tomašič, Roland J. Pieters, Martina Gobec, Marko Anderluh
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
O-GlcNAcylation is an important post-translational and metabolic process in cells that must be carefully regulated. O-GlcNAc transferase (OGT) is ubiquitously present in cells and is the only enzyme that catalyzes the transfer of O-GlcNAc to proteins
Externí odkaz:
https://doaj.org/article/bed20003ff6f4e85991d320f8a84b5ec
Publikováno v:
ACS Central Science, Vol 5, Iss 9, Pp 1514-1522 (2019)
Externí odkaz:
https://doaj.org/article/95a766a0c4fc4b88aaab52f32bec4872