Výsledky vyhledávání - "Roland Hessler"

Akademický článek

Cochlear implant electrode design for safe and effective treatment

Autor: Anandhan Dhanasingh, Stefan Bryde Nielsen, Fabrice Beal, Soeren Schilp, Roland Hessler, Claude Jolly, Ingeborg Hochmair

Publikováno v: Frontiers in Neurology, Vol 15 (2024)

The optimal placement of a cochlear implant (CI) electrode inside the scala tympani compartment to create an effective electrode–neural interface is the base for a successful CI treatment. The characteristics of an effective electrode design includ

Externí odkaz: https://doaj.org/article/0dbc8a46edca46a188ce0091065861fe

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Akademický článek

Otoprotection to Implanted Cochlea Exposed to Noise Trauma With Dexamethasone Eluting Electrode

Autor: Adrien A. Eshraghi, Amit Wolfovitz, Rasim Yilmazer, Carolyn Garnham, Ayca Baskadem Yilmazer, Esperanza Bas, Peter Ashman, Jonathan Roell, Jorge Bohorquez, Rahul Mittal, Roland Hessler, Daniel Sieber, Jeenu Mittal

Publikováno v: Frontiers in Cellular Neuroscience, Vol 13 (2019)

Cochlear implantation (CI) is now widely used to provide auditory rehabilitation to individuals having severe to profound sensorineural hearing loss (SNHL). However, CI can lead to electrode insertion trauma (EIT) that can cause damage to sensory cel

Externí odkaz: https://doaj.org/article/a6a48966952043ef9db7e96b7e382ffb

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Akademický článek

Local inner ear application of dexamethasone in cochlear implant models is safe for auditory neurons and increases the neuroprotective effect of chronic electrical stimulation.

Autor: Verena Scheper, Roland Hessler, Mareike Hütten, Maciej Wilk, Claude Jolly, Thomas Lenarz, Gerrit Paasche

Publikováno v: PLoS ONE, Vol 12, Iss 8, p e0183820 (2017)

Dexamethasone (DEX) can reduce fibrous tissue growth as well as loss of residual hearing which may occur after cochlear implantation. Little is known about the effect of local inner ear DEX treatment on the spiral ganglion neurons (SGN), which are th

Externí odkaz: https://doaj.org/article/33bfa80c722b4f9e8d4c1d0c7a45be3c

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Akademický článek

Impedance Changes and Fibrous Tissue Growth after Cochlear Implantation Are Correlated and Can Be Reduced Using a Dexamethasone Eluting Electrode.

Autor: Maciej Wilk, Roland Hessler, Kenneth Mugridge, Claude Jolly, Michael Fehr, Thomas Lenarz, Verena Scheper

Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0147552 (2016)

BACKGROUND:The efficiency of cochlear implants (CIs) is affected by postoperative connective tissue growth around the electrode array. This tissue formation is thought to be the cause behind post-operative increases in impedance. Dexamethasone (DEX)

Externí odkaz: https://doaj.org/article/2a6401c8f85d467fbdaa0f17268b742c

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Akademický článek

In vitro and in vivo evaluation of a hydrogel reservoir as a continuous drug delivery system for inner ear treatment.

Autor: Mareike Hütten, Anandhan Dhanasingh, Roland Hessler, Timo Stöver, Karl-Heinz Esser, Martin Möller, Thomas Lenarz, Claude Jolly, Jürgen Groll, Verena Scheper

Publikováno v: PLoS ONE, Vol 9, Iss 8, p e104564 (2014)

Fibrous tissue growth and loss of residual hearing after cochlear implantation can be reduced by application of the glucocorticoid dexamethasone-21-phosphate-disodium-salt (DEX). To date, sustained delivery of this agent to the cochlea using a number

Externí odkaz: https://doaj.org/article/358a3ba4f8a54f6a8225d80c8e674511

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Multiscale photonic imaging of the native and implanted cochlea

Autor: Alexander C. Meyer, Christian Vogl, Mareike Töpperwien, Tobias Moser, Carlos J. Duque-Afonso, Daniel Keppeler, Tim Salditt, Tabea Quilitz, Christoph A. Kampshoff, Roland Hessler, Jannis Schaeper, Anupriya Thirumalai

Publikováno v: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the USA

The cochlea of our auditory system is an intricate structure deeply embedded in the temporal bone. Compared with other sensory organs such as the eye, the cochlea has remained poorly accessible for investigation, for example, by imaging. This limitat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcbe0307ea507caf1723ae383ffbc8a
https://doi.org/10.1073/pnas.2014472118

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Hearing restoration by a low-weight power-efficient multichannel optogenetic cochlear implant system

Autor: Bettina Wolf, Patrick Ruther, Gerhard Hoch, Suleman Ayub, Roland Hessler, Lukasz Jablonski, Tobias Moser, Alexander Dieter, Tamas Harczos

In case of deafness, cochlear implants bypass dysfunctional or lost hair cells by direct electrical stimulation (eCIs) of the auditory nerve. However, spectral selectivity of eCI sound coding is low as the wide current spread from each electrode acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99e5b134f65d58d1bf77da011184f1d3
https://doi.org/10.1101/2020.05.25.114868

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Local inner ear application of dexamethasone in cochlear implant models is safe for auditory neurons and increases the neuroprotective effect of chronic electrical stimulation

Autor: Mareike Hütten, Verena Scheper, Maciej Wilk, Claude Jolly, Roland Hessler, Thomas Lenarz, Gerrit Paasche

Publikováno v: PLoS ONE
PLOS ONE
PLoS ONE, Vol 12, Iss 8, p e0183820 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038b022fccb6d9c7dfb1f5ab07a7180a
https://pubmed.ncbi.nlm.nih.gov/28859106

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Impedance Changes and Fibrous Tissue Growth after Cochlear Implantation Are Correlated and Can Be Reduced Using a Dexamethasone Eluting Electrode

Autor: Roland Hessler, Maciej Wilk, Kenneth Mugridge, Thomas Lenarz, Michael Fehr, Verena Scheper, Claude Jolly

Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0147552 (2016)
PLoS ONE

Background The efficiency of cochlear implants (CIs) is affected by postoperative connective tissue growth around the electrode array. This tissue formation is thought to be the cause behind post-operative increases in impedance. Dexamethasone (DEX)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebb65961ace0de860e6b70a1ca00811
http://europepmc.org/articles/PMC4739581?pdf=render

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Propagation-based phase-contrast tomography of a guinea pig inner ear with cochlear implant using a model-based iterative reconstruction algorithm

Autor: Benedikt Günther, Joerg Hammel, Lorenz Hehn, Werner Hemmert, Kaye S. Morgan, Christoph Jud, Regine Gradl, Martin Dierolf, Sebastian Allner, Konstantin Willer, Julia Herzen, Andrej Voss, Franz Pfeiffer, Roland Hessler

Publikováno v: Biomedical optics express 9(11), 5330-5339 (2018). doi:10.1364/BOE.9.005330
Hehn, L.; Gradl, R.; Voss, A.; Guenther, B.; Dierolf, M.; Jud, C.; Willer, K.; Allner, S.; Hammel, J.U.; Hessler, R.; Morgan, K.S.; Herzen, J.; Hemmert, W.; Pfeiffer, F.: Propagation-based phase-contrast tomography of a guinea pig inner ear with cochlear implant using a model-based iterative reconstruction algorithm. In: Biomedical Optics Express. Vol. 9 (2018) 11, 5330-5339. (DOI: /10.1364/BOE.9.005330)
Biomedical Optics Express

Biomedical optics express 9(11), 5330 - 5339 (2018). doi:10.1364/BOE.9.005330
Propagation-based phase-contrast computed tomography has become a valuable tool for visualization of three-dimensional biological samples, due to its high contrast bet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69ce17afadd9e596f6fcb033870475a
https://doi.org/10.1364/boe.9.005330

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