Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Roland Gromes"'
Autor:
Shanshan Wang, Thomas Rausch, Klaus Scheffzek, Markus Wirtz, Esther D. Lenherr, Roland Gromes, Rüdiger Hell, Yingxue Yang, Tanja Peskan-Berghöfer
Publikováno v:
Biochemical Journal
'Biochemical Journal ', vol: 476, pages: 1191-1203 (2019)
'Biochemical Journal ', vol: 476, pages: 1191-1203 (2019)
Plant γ-glutamylcysteine ligase (GCL), catalyzing the first and tightly regulated step of glutathione (GSH) biosynthesis, is redox-activated via formation of an intramolecular disulfide bond. In vitro, redox-activation of recombinant GCL protein cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed1efabb573b31be3c641d1985c28ea
https://pubmed.ncbi.nlm.nih.gov/30877193
https://pubmed.ncbi.nlm.nih.gov/30877193
Autor:
Sanja Matern, Rebecca Vazquez Kiesel, Roland Gromes, Thomas Rausch, Tatjana Peskan-Berghoefer
Publikováno v:
Journal of Experimental Botany
Highlight Transgenically imposed high glutathione, uncoupled from cellular controls, causes an oxidative shift in cytosolic redox potential, activates tobacco MAPKs, and primes immune responses to adapted and non-adapted Pseudomonas syringae pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2343c37abf10832d38a0b30a78375b5c
http://europepmc.org/articles/PMC4378631
http://europepmc.org/articles/PMC4378631
Autor:
Esther D. Lenherr, Michael Hothorn, Roland Gromes, Klaus Scheffzek, Vladimir Rybin, Thomas Rausch
Publikováno v:
The Plant Journal. 54:1063-1075
SummaryIn plants, the first committed enzyme for glutathione biosynthesis, c-glutamylcysteine ligase (GCL), is undermultiple controls. The recent elucidation of GCL structure from Brassica juncea (BjGCL) has revealed thepresence of two intramolecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326c4e2ad477445d4662325c8f0d32c0
https://doi.org/10.1111/j.1365-313x.2008.03477.x
https://doi.org/10.1111/j.1365-313x.2008.03477.x
Autor:
Jürgen Kopitz, Hans-Joachim Gabius, Georgios Patsos, Sabine André, Johannes Gebert, Nina Roeckel, Roland Gromes
Publikováno v:
Glycobiology. 19(7)
Tumors that display a high level of microsatellite instability (MSI-H) accumulate somatic frameshift mutations in several genes. The compensation of this loss of function by transfection represents a suitable approach to tie respective gene deficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca71d597964dd6d1cd7fb80c9fca278
https://pubmed.ncbi.nlm.nih.gov/19293232
https://pubmed.ncbi.nlm.nih.gov/19293232
Autor:
Stefan M. Woerner, Georgios Patsos, Yan-Ping Yuan, Matthias Kloor, Johannes Gebert, Nina Roeckel, Roland Gromes, Juergen Kopitz
Publikováno v:
Cancer research. 69(1)
Glycosyl epitopes have been identified as tumor-specific markers in colorectal tumors and various lines of evidence indicate the significance of altered synthesis, transport, and secretion of glycoproteins in tumorigenesis. However, aberrant glycosyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200d5154eaaf3f39a135e1c8007f8e47
https://pubmed.ncbi.nlm.nih.gov/19118014
https://pubmed.ncbi.nlm.nih.gov/19118014
Autor:
I. Müller, Jochen Bogs, Andreas Wachter, Thomas Rausch, V. Galovic, Roland Gromes, V. Liedschulte
Publikováno v:
Plant biology (Stuttgart, Germany). 9(5)
In higher plants, the redox-active tripeptide glutathione (GSH) fulfills a plethora of functions. These include its pivotal role for maintaining the cellular redox poise and its involvement in detoxification of heavy metals and xenobiotics. Intimatel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bac0de5d568292ec1104dd5a1aab0b2
https://pubmed.ncbi.nlm.nih.gov/17853356
https://pubmed.ncbi.nlm.nih.gov/17853356
Publikováno v:
Journal of experimental botany. 57(14)
The protective function of a plant type-2 metallothionein was analysed after expression in Escherichia coli and in Arabidopsis thaliana seedlings. BjMT2 from Brassica juncea was expressed in E. coli as a TrxABjMT2 fusion protein. After affinity chrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46baad963b73c4a9c2d0836ea7f6ec8
https://pubmed.ncbi.nlm.nih.gov/16957018
https://pubmed.ncbi.nlm.nih.gov/16957018
Autor:
Thomas Rausch, Klaus Scheffzek, Tobias Stuwe, Roland Gromes, Andreas Wachter, Michael Hothorn
Publikováno v:
The Journal of biological chemistry. 281(37)
Glutathione (GSH) plays a crucial role in plant metabolism and stress response. The rate-limiting step in the biosynthesis of GSH is catalyzed by glutamate cysteine ligase (GCL) the activity of which is tightly regulated. The regulation of plant GCLs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15e76be679c9e0d0ce930946fc87217
https://pubmed.ncbi.nlm.nih.gov/16766527
https://pubmed.ncbi.nlm.nih.gov/16766527
Autor:
Georgios Patsos, Sabine André, Nina Roeckel, Roland Gromes, Johannes Gebert, Jürgen Kopitz, Hans-Joachim Gabius
Publikováno v:
Glycobiology; Jul2009, Vol. 19 Issue 7, p726-726, 1p