Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Roland Geisberger"'
Autor:
Thomas Parigger PhD, Franz Josef Gassner PhD, Stephan Drothler MSc, Christian Scherhäufl MSc, Alexandra Hödlmoser MSc, Lena Schultheis MSc, Aryunni Abu Bakar MSc, Florian Huemer MD, Richard Greil MD, Roland Geisberger PhD, Lukas Weiss MD, PhD, Nadja Zaborsky PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 23 (2024)
Objectives: In this study, stool samples were evaluated for tumor mutation analysis via a targeted next generation sequencing (NGS) approach in a small patient cohort suffering from localized rectal cancer. Introduction: Colorectal cancer (CRC) cause
Externí odkaz:
https://doaj.org/article/9444f640bdc84627b111c7918a84a93d
Autor:
Marc Vaisband, Maria Schubert, Franz Josef Gassner, Roland Geisberger, Richard Greil, Nadja Zaborsky, Jan Hasenauer
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Accurate somatic variant calling from next-generation sequencing data is one most important tasks in personalised cancer therapy. The sophistication of the available technologies is ever-increasing, yet, manual candidate refinement is still
Externí odkaz:
https://doaj.org/article/6354773ffd1345a882925ecef572ccef
Publikováno v:
Pharmaceuticals, Vol 14, Iss 2, p 89 (2021)
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by binding to complementary target regions on gene transcripts. Thus, miRNAs fine-tune gene expression profiles in a cell-type-specific manner and thereby regulate important c
Externí odkaz:
https://doaj.org/article/2ef30622844e46da87665906abebda6e
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208753 (2018)
Activation induced deaminase (AID) has two distinct and well defined roles, both relying on its deoxycytidine (dC) deaminating function: one as a DNA mutator and another in DNA demethylation. In chronic lymphocytic leukemia (CLL), AID was previously
Externí odkaz:
https://doaj.org/article/501cb474db334f3da5fa5d118a969bc8
Autor:
Kemal Catakovic, Franz Josef Gassner, Christoph Ratswohl, Nadja Zaborsky, Stefan Rebhandl, Maria Schubert, Markus Steiner, Julia Christine Gutjahr, Lisa Pleyer, Alexander Egle, Tanja Nicole Hartmann, Richard Greil, Roland Geisberger
Publikováno v:
OncoImmunology, Vol 7, Iss 1 (2018)
While research on T cell exhaustion in context of cancer particularly focuses on CD8+ cytotoxic T cells, the role of inhibitory receptors on CD4+ T-helper cells have remained largely unexplored. TIGIT is a recently identified inhibitory receptor on T
Externí odkaz:
https://doaj.org/article/3efacdabf869402ea59e8d5004d73427
Autor:
Simon Auer, Mark Rinnerthaler, Johannes Bischof, Maria Karolin Streubel, Hannelore Breitenbach-Koller, Roland Geisberger, Elmar Aigner, Janne Cadamuro, Klaus Richter, Mentor Sopjani, Elisabeth Haschke-Becher, Thomas Klaus Felder, Michael Breitenbach
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
NADPH oxidases of human cells are not only functional in defense against invading microorganisms and for oxidative reactions needed for specialized biosynthetic pathways but also during the past few years have been established as signaling modules. I
Externí odkaz:
https://doaj.org/article/bce0d497c3664b568e8740e6ef03cc0e
Autor:
Nadja Zaborsky, Claudia Holler, Roland Geisberger, Daniela Asslaber, Franz Josef Gassner, Viktoria Egger, Josephina Piñón-Hofbauer, Thomas Kocher, Tanja Nicole Hartmann, Richard Greil, Alexander Egle
Publikováno v:
Haematologica, Vol 100, Iss 8 (2015)
Externí odkaz:
https://doaj.org/article/0b4d4953d9284d25af19a34fe3c30c55
Autor:
Roland Geisberger, Martin Prlic, Gertrude Achatz-Straussberger, Iris Oberndorfer, Elke Luger, Marinus Lamers, Reto Crameri, Ulrich Appenzeller, Jürgen Wienands, Michael Breitenbach, Fatima Ferreira, Gernot Achatz
Publikováno v:
Clinical and Developmental Immunology, Vol 9, Iss 3, Pp 127-134 (2002)
Externí odkaz:
https://doaj.org/article/6734f0cbdf6d4e498cfab259841a9931
Autor:
Franz J. Gassner, Nadja Zaborsky, Daniel Neureiter, Michael Huemer, Thomas Melchardt, Alexander Egle, Stefan Rebhandl, Kemal Catakovic, Tanja N. Hartmann, Richard Greil, Roland Geisberger
Publikováno v:
Haematologica, Vol 99, Iss 5 (2014)
Externí odkaz:
https://doaj.org/article/cf59dc8cea5a4ba6a0a256b4eaf0cd79
Autor:
Roland Geisberger, Michael Huemer, Franz J Gassner, Nadja Zaborsky, Alexander Egle, Richard Greil
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30667 (2012)
BackgroundActivation induced deaminase (AID) mediates class switch recombination and somatic hypermutation of immunoglobulin (Ig) genes in germinal centre B cells. In order to regulate its specific activity and as a means to keep off-target mutations
Externí odkaz:
https://doaj.org/article/533339129a9440998e388d3f4e33ace4