Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Roland G, Stein"'
Autor:
Michel Mittelbronn, Itsaso Montalbán del Barrio, Cornelia Penski, Laura Schlahsa, Roland G. Stein, Joachim Diessner, Achim Wöckel, Johannes Dietl, Manfred B. Lutz, Jörg Wischhusen, Sebastian F. M. Häusler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 4, Iss 1 (2016)
Background Ovarian cancer (OvCA) tissues show abundant expression of the ectonucleotidases CD39 and CD73 which generate immunomodulatory adenosine, thereby inhibiting cytotoxic lymphocytes. Little, however, is known about the effect of adenosine on m
Externí odkaz:
https://doaj.org/article/a2fb9b47e44d490bb348f9a5c0c1c988
Autor:
Roland G, Stein, Stefan, Ebert, Laura, Schlahsa, Claus J, Scholz, Matthias, Braun, Petra, Hauck, Evi, Horn, Camelia-Maria, Monoranu, Vincent J, Thiemann, Michael P, Wustrow, Sebastian F, Häusler, Itsaso, Montalbán Del Barrio, Tanja N, Stüber, Matthias, Wölfl, Johannes, Dietl, Andreas, Rosenwald, Joachim E, Diessner, Achim, Wöckel, Jörg, Wischhusen
Publikováno v:
Cancer research. 79(7)
Targeting of tumor immune escape mechanisms holds enormous therapeutic potential. Still, most patients progress under immune checkpoint blockade and some even become hyperprogressors. To investigate how cancer cells respond to activated but ineffecti
Autor:
Itsaso, Montalbán Del Barrio, Cornelia, Penski, Laura, Schlahsa, Roland G, Stein, Joachim, Diessner, Achim, Wöckel, Johannes, Dietl, Manfred B, Lutz, Michel, Mittelbronn, Jörg, Wischhusen, Sebastian F M, Häusler
Publikováno v:
Journal for Immunotherapy of Cancer
Background Ovarian cancer (OvCA) tissues show abundant expression of the ectonucleotidases CD39 and CD73 which generate immunomodulatory adenosine, thereby inhibiting cytotoxic lymphocytes. Little, however, is known about the effect of adenosine on m
Autor:
Sebastian Fm, Häusler, Itsaso Montalbán, Del Barrio, Joachim, Diessner, Roland G, Stein, Jenny, Strohschein, Arnd, Hönig, Johannes, Dietl, Jörg, Wischhusen
Publikováno v:
American journal of translational research. 6(2)
The ectonucleotidases CD39 and CD73 degrade ATP to adenosine which inhibits immune responses via the A2A adenosine receptor (ADORA2A) on T and NK cells. The current study investigates the potential therapeutic use of the specific anti CD39- and anti