Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Roland Furstoss"'
Publikováno v:
Advanced Synthesis & Catalysis. 349:2049-2053
Cells of Escherichia coli expressing cyclo- hexanone monooxygenase catalyzed a highly enan- tioselective Baeyer-Villiger oxidation of a-substi- tuted cyanocyclohexanones, leading to the corre- sponding enantiopure caprolactones (ees > 97 %). Classica
Publikováno v:
Advanced Synthesis & Catalysis. 349:1405-1417
The aim of this work was to perform dif- ferent studies allowing us to improve the methodolo- gy we had previously described to realise the Asper- gillus niger epoxide hydrolase-catalysed resolution of eight trifluoromethyl-substituted styrene oxide
Publikováno v:
Tetrahedron: Asymmetry. 18:1233-1238
The covalent immobilization of the Solanum tuberosum epoxide hydrolase (StEH) was explored using highly activated Sepabeads-epoxy or Glyoxyl-agarose based supports. A Glyoxyl-agarose immobilizate, prepared under optimized experimental conditions, led
Publikováno v:
Advanced Synthesis & Catalysis. 348:1948-1957
The hydrolytic kinetic resolution of five glycidaldehyde acetal derivatives was examined using the recombinant Aspergillus niger epoxide hy- drolase as biocatalyst. This could successfully be per- formed, at room temperature, using solely deminer- al
Publikováno v:
Advanced Synthesis & Catalysis. 348:1165-1169
The resolution of eight differently substituted trifluoromethylstyrene oxide derivatives was explored using the Aspergillus niger epoxide hydrolase. The obtained results indicate that all (but one) epoxides were efficiently processed by this enzyme,
Publikováno v:
Organic Process Research & Development. 10:599-604
Microbial Baeyer−Villiger oxidation of different substrates with cyclopentanone monooxygenase (CPMO) from Comamonas NCIMB 9872 was up-scaled to benchtop fermenter scale. Conditions for cell growth and biocatalyst production were optimized, and a co
Publikováno v:
Advanced Synthesis & Catalysis. 347:1051-1059
A dynamic kinetic resolution process was applied to an enantioconvergent microbial Baeyer-Villiger oxidation of benzyloxycyclopentanone, rac-1. This was achieved by combining a whole cell-based kinetic resolution and an anion exchange resin-catalysed
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 32:175-183
Recombinant epoxide hydrolase (EH) from Aspergillus niger can be a very promising tool for the resolution of various racemic epoxides by enantioselective hydrolysis. The enzyme was successfully immobilized by ionic adsorption onto DEAE-cellulose (99%
Publikováno v:
Biocatalysis and Biotransformation. 23:397-405
Five supports have been evaluated for the immobilization of the epoxide hydrolase from Solanum tuberosum (StEH) by adsorption. The highest immobilization yield (90–99%) and the maximum EH (epoxide hydrolase) activity (0.6 U g−1 wet support) were
Publikováno v:
Advanced Synthesis & Catalysis. 346:203-214
An efficient preparative scale process for achieving asymmetric Baeyer±Villiger oxidation ± a reaction still very difficult to perform using conven- tional chemistry ± is described. This process is based on a biocatalytic whole cells strategy ± u