Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Roland F. Dreier"'
Autor:
Katharina S. Schneider, Christina J. Groß, Roland F. Dreier, Benedikt S. Saller, Ritu Mishra, Oliver Gorka, Rosalie Heilig, Etienne Meunier, Mathias S. Dick, Tamara Ćiković, Jan Sodenkamp, Guillaume Médard, Ronald Naumann, Jürgen Ruland, Bernhard Kuster, Petr Broz, Olaf Groß
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3846-3859 (2017)
Inflammasomes activate the protease caspase-1, which cleaves interleukin-1β and interleukin-18 to generate the mature cytokines and controls their secretion and a form of inflammatory cell death called pyroptosis. By generating mice expressing enzym
Externí odkaz:
https://doaj.org/article/caf0ef9e648d468094e235c5382d0983
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The pathogenicity ofFrancisellaspecies largely depends on their escape from phagosomes in macrophages, mediated by a type VI secretion system (T6SS). Here, the authors show dynamics of T6SS assembly and disassembly and identify the genes essential fo
Externí odkaz:
https://doaj.org/article/219e24a7c4a6467a9aed759dbf29e440
Autor:
Markus P Schlaich, Marc Bellet, Michael A Weber, Parisa Danaietash, George L Bakris, John M Flack, Roland F Dreier, Mouna Sassi-Sayadi, Lloyd P Haskell, Krzysztof Narkiewicz, Ji-Guang Wang, Christopher Reid, Markus Schlaich, Ivor Katz, Andrew Ajani, Sinjini Biswas, Murray Esler, Grahame Elder, Simon Roger, David Colquhoun, John Mooney, Tine De Backer, Alexandre Persu, Martin Chaumont, Jean-Marie Krzesinski, Thomas Vanassche, Ginette Girard, Lew Pliamm, Ernesto Schiffrin, Fatima Merali, George Dresser, Michel Vallee, Shivinder Jolly, Stephen Chow, Jiguang Wang, Jianjun Mu, Jing Yu, Hong Yuan, Yingqing Feng, Xin Zhang, Jianhong Xie, Ling Lin, Miroslav Soucek, Jiri Widimsky, Renata Cifkova, Jan Vaclavik, Martin Ullrych, Martin Lukac, Ivan Rychlik, Thomas Guldager Lauridsen, Ilkka Kantola, Jyrki Taurio, Olavi Ukkola, Olivier Ormezzano, Philippe Gosse, Michel Azizi, Pierre-Yves Courand, Pascal Delsart, Jean Michel Tartiere, Felix Mahfoud, Roland Schmieder, Johannes Stegbauer, Philipp Lurz, Michael Koziolek, Christian Ott, Nicole Toursarkissian, Konstantinos Tsioufis, Konstantinos Kyfnidis, Athanasios Manolis, Sotirios Patsilinakos, Pantelis Zebekakis, Apostolos Karavidas, Pall Denes, Katalin Bezzegh, Marianna Zsom, Laszlo Kovacs, Yehonatan Sharabi, Mazen Elias, Ivetta Sukholutsky, Chaim Yosefy, Irina Kenis, Shaul Atar, Massimo Volpe, Muiesan Maria Lorenza, Stefano Taddei, Guido Grassi, Franco Veglio, Jung Woo Son, Jang-Young Kim, Joong-Il Park, Chang Hoon Lee, Hae-Young Lee, Rasa Raugaliene, Jolanta Elena Marcinkeviciene, Roma Kavaliauskiene, Jaap Deinum, Abraham Kroon, Bert-Jan van den Born, Andrzej Januszewicz, Andrzej Tykarski, Jolanta Walczewska, Zbigniew Gaciong, Andrzej Wiecek, Marzena Chrostowska, Andrzej Kleinrok, Jan Krekora, Grzegorz Kania, Anna Podrazka-Szczepaniak, Cezary Golawski, Maciej Podziewski, Barbara Kaczmarek, Grzegorz Skoczylas, Andrzej Wilkolaski, Iwona Wozniak, Marzena Janik-Palazzolo, Barbara Rewerska, Aleksandra Konradi, Yuriy Shvarts, Tamara Pecherina, Konstantin Nikolaev, Gapon Liudmila, Olga Orlikova, Viktor Mordovin, Natalia Petrochenkova, Gadel Kamalov, Elena Kosmacheva, Vadim Tyrenko, Vladimir Gorbunov, Andrey Obrezan, Tatiana Supryadkina, Irina Ler, Oleg Kotenko, Anatoly Kuzin, Fernando Martínez García, Josep Redon, Anna Oliveras, Luis Beltran Romero, Valerii Shatylo, Leonid Rudenko, Andriy Bazylevych, Yurii Rudyk, Oleksandr Karpenko, Mykola Stanislavchuk, Vira Tseluyko, Mykola Kushnir, Ervin Asanov, Yuriy Sirenko, Andriy Yagensky, David Collier, Pankaj Gupta, David Webb, Mary MacLeod, James McLay, Aaron Peace, Samir Arora, Patricia Buchanan, Robert Harris, Ronald Degarmo, Mario Guillen, Adam Karns, Joel Neutel, Yogesh Paliwal, Karlton Pettis, Phillip D. Toth, Jeffrey M. Wayne, Michael Bain Butcher, Phillip M. Diller, Suzanne Oparil, David Calhoun, Donald Brautigam, John Flack, Jesse M. Goldman, Arash Rashidi, Nabeel Aslam, William Haley, Nabil Andrawis, Brian Lang, Randy Miller, James Powell, Robert Dewhurst, James Pritchard, Dinesh Khanna, Dennis Tang, Nashwa Gabra, Jean Park, Conigliaro Jones, Cranford Scott, Blanca Luna, Murtaza Mussaji, Ravi Bhagwat, Michael Bauer, John McGinty, Rajesh Nambiar, Renee Sangrigoli, William Ross Davis, William Eaves, Frank McGrew, Ahmed Awad, Eric Bolster, David Scott, Paramjit Kalirao, Pascal Dabel, Wesley Calhoun, Steven Gouge, Mark Warren, Mary Katherine Lawrence, Aamir Jamal, Mohamed El-Shahawy, Carlos Mercado, Jayant Kumar, Pedro Velasquez-Mieyer, Robert Busch, Todd Lewis, Lisa Rich
Publikováno v:
The Lancet (London), 400, 1927-1937
The Lancet, 400(10367), 1927-1937. Elsevier Limited
The Lancet (London), 400, 10367, pp. 1927-1937
The Lancet, 400(10367), 1927-1937. Elsevier Limited
The Lancet (London), 400, 10367, pp. 1927-1937
Contains fulltext : 286841.pdf (Publisher’s version ) (Closed access) BACKGROUND: Resistant hypertension is associated with increased cardiovascular risk. The endothelin pathway has been implicated in the pathogenesis of hypertension, but it is cur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8661784163094e06b4019a9c7edb043
http://hdl.handle.net/2066/286841
http://hdl.handle.net/2066/286841
Autor:
Roland F. Dreier, Ritu Mishra, Jürgen Ruland, Katharina S. Schneider, Tamara Cikovic, Jan Sodenkamp, Oliver Gorka, Ronald Naumann, Rosalie Heilig, Mathias S. Dick, Petr Broz, Etienne Meunier, Benedikt S. Saller, Christina J. Groß, Bernhard Kuster, Olaf Groß, Guillaume Médard
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3846-3859 (2017)
Cell Reports
Cell reports, vol. 21, no. 13, pp. 3846-3859
Cell Reports
Cell reports, vol. 21, no. 13, pp. 3846-3859
Summary Inflammasomes activate the protease caspase-1, which cleaves interleukin-1β and interleukin-18 to generate the mature cytokines and controls their secretion and a form of inflammatory cell death called pyroptosis. By generating mice expressi
Autor:
Roland F. Dreier, Julien M. Buyck, Olivier Cunrath, Petr Broz, Rémi Planès, Dirk Bumann, Emmanuelle Naser, Elif Eren, José Carlos Santos, Valérie Duplan-Eche, Agnès Coste, Olivier Neyrolles, Etienne Meunier, Pierre-Jean Bordignon, Céline Cougoule, André Colom, Antonio Peixoto
Inflammasome-induced pyroptosis comprises a key cell-autonomous immune process against intracellular bacteria, namely the generation of dying cell structures. These so-called pore-induced intracellular traps (PITs) entrap and weaken intracellular mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec63d439306912927ae83221b6b359d
https://doi.org/10.1101/650333
https://doi.org/10.1101/650333
Publikováno v:
Journal of proteome research. 18(1)
Mass spectrometry based proteomics has become the method of choice for pinpointing and monitoring thousands of post-translational modifications, predominately phosphorylation sites, in cellular signaling studies. Critical for achieving this analytica
Publikováno v:
Methods in Molecular Biology ISBN: 9781493975181
Recognition of pathogens by the innate immune system relies on germline-encoded pattern recognition receptors (PRRs) that recognize unique microbial molecules, so-called pathogen-associated molecular patterns (PAMPs). Nucleic acids and their derivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38aa5362bcc7e1bfe1fd18963fc14b31
https://doi.org/10.1007/978-1-4939-7519-8_13
https://doi.org/10.1007/978-1-4939-7519-8_13
Autor:
Mathias S. Dick, Mélanie Rigard, Sébastien Dussurgey, Klaus Pfeffer, Anne Kistner, Roland F. Dreier, Leonie Anton, Pierre Wallet, Masahiro Yamamoto, Stéphanie Costanzo, Etienne Meunier, Sebastian Rühl, Daniel Degrandi, Petr Broz, Thomas Henry
Publikováno v:
Nature Immunology
Nature Immunology, Nature Publishing Group, 2015, 16 (5), pp.476-484. ⟨10.1038/ni.3119⟩
Nature Immunology, 2015, 16 (5), pp.476-484. ⟨10.1038/ni.3119⟩
NATURE IMMUNOLOGY
Nature immunology
Nature Immunology, Nature Publishing Group, 2015, 16 (5), pp.476-484. ⟨10.1038/ni.3119⟩
Nature Immunology, 2015, 16 (5), pp.476-484. ⟨10.1038/ni.3119⟩
NATURE IMMUNOLOGY
Nature immunology
The AIM2 inflammasome detects double-stranded DNA in the cytosol and induces caspase-1-dependent pyroptosis as well as release of the inflammatory cytokines interleukin 1β (IL-1β) and IL-18. AIM2 is critical for host defense against DNA viruses and
Autor:
Erik Ahrné, Cécile Arrieumerlou, Christoph Kasper, Roland F. Dreier, Therese Tschon, Alexander Schmidt, Christoph Schmutz, Isabel Sorg
Publikováno v:
Molecular and cellular proteomics
The enteroinvasive bacterium Shigella flexneri invades the intestinal epithelium of humans. During infection, several injected effector proteins promote bacterial internalization, and interfere with multiple host cell responses. To obtain a systems-l
Autor:
Petr Broz, Dirk Bumann, Søren Warming, Masahiro Yamamoto, Nura Schürmann, Mathias S. Dick, Nobuhiko Kayagaki, Merone Roose-Girma, Daniela Kenzelmann Broz, Kiyoshi Takeda, Roland F. Dreier, Etienne Meunier
Publikováno v:
NATURE
Lipopolysaccharide from Gram-negative bacteria is sensed in the host cell cytoplasm by a non-canonical inflammasome pathway that ultimately results in caspase-11 activation and cell death. In mouse macrophages, activation of this pathway requires the