Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Roland, Ruscher"'
Autor:
David Williams, Gabrielle Belz, Wei Shi, Anita Kumari, Andreas Behren, Maxine Smith, Marina Yakou, Sonia Ghilas, Kelly Tran, Yang Liao, Shoukat Afshar-Sterle, Kevin Schmid, Christine Dijkstra, Chantelle Inguanti, Simone Ostrouska, Jordan Wilcox, Pavitha Parathan, Amr Allam, Hai-Hui Xue, John Mariadason, Grant Drummond, Roland Ruscher, Bhupinder Pal, Matthias Ernst, Dinesh Raghu, Lisa A Mielke
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/53e2c7996d52481f9160ae107e1bb5fa
Autor:
Claudia Cobos, Paramjit S. Bansal, David T. Wilson, Linda Jones, Guangzu Zhao, Matthew A. Field, Ramon M. Eichenberger, Darren A. Pickering, Rachael Y. M. Ryan, Champa N. Ratnatunga, John J. Miles, Roland Ruscher, Paul R. Giacomin, Severine Navarro, Alex Loukas, Norelle L. Daly
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
A decline in the prevalence of parasites such as hookworms appears to be correlated with the rise in non-communicable inflammatory conditions in people from high- and middle-income countries. This correlation has led to studies that have identified p
Externí odkaz:
https://doaj.org/article/a3c34398fda94a3db5634fff4a84d84c
Publikováno v:
Plants, Vol 11, Iss 19, p 2519 (2022)
Plants have been a vital source of natural antioxidants since ancient times. Plants growing under various abiotic stress conditions often produce more defensive secondary metabolites such as phenolics, flavonoids, and terpenoids during adaptation to
Externí odkaz:
https://doaj.org/article/dfb4a86afc164c3d9fa9a111d719b642
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008508 (2020)
Parasitic helminths have coevolved with humans over millennia, intricately refining and developing an array of mechanisms to suppress or skew the host's immune system, thereby promoting their long-term survival. Some helminths, such as hookworms, cau
Externí odkaz:
https://doaj.org/article/dc6b35d74f754efdbc361b8225386e5d
Autor:
Brendan J. O’Sullivan, Suman Yekollu, Roland Ruscher, Ahmed M. Mehdi, Muralidhara Rao Maradana, Ann P. Chidgey, Ranjeny Thomas
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Polymorphisms impacting thymic function may decrease peripheral tolerance and hasten autoimmune disease. The NF-κB transcription factor subunit, RelB, is essential for the development and differentiation of medullary thymic epithelial cells (mTECs):
Externí odkaz:
https://doaj.org/article/cb59225cab8e4e9d8a701100700b5698
Autor:
Roland Ruscher, Kristin Hogquist
Publikováno v:
Bio-Protocol, Vol 8, Iss 5 (2018)
Following development in the thymus, T cells are thought to exit into the periphery predominantly through perivascular spaces (PVS). This exit route is used by conventional T cells, and likely also applies to unconventional T cell subsets, such as pr
Externí odkaz:
https://doaj.org/article/02717b6b203e4384b502e463bc7b3bd0
Publikováno v:
Frontiers in Parasitology. 1
Parasitic helminths secrete and excrete a vast array of molecules known to help skew or suppress the host’s immune response, thereby establishing a niche for sustained parasite maintenance. Indeed, the immunomodulatory potency of helminths is attri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0921e010e71d355c5c7c8e53407b283
https://doi.org/10.3389/fpara.2022.984152
https://doi.org/10.3389/fpara.2022.984152
Autor:
Stephanie M. Ryan, Roland Ruscher, Wayne A. Johnston, Darren A. Pickering, Malcolm W. Kennedy, Brian O. Smith, Linda Jones, Geraldine Buitrago, Matt A. Field, Adrian J. Esterman, Connor P. McHugh, Daniel J. Browne, Martha M. Cooper, Rachael Y. M. Ryan, Denise L. Doolan, Christian R. Engwerda, Kim Miles, Makedonka Mitreva, John Croese, Tony Rahman, Kirill Alexandrov, Paul R. Giacomin, Alex Loukas
Refereed/Peer-reviewed Parasitic helminth infections, while a major cause of neglected tropical disease burden, negatively correlate with the incidence of immune-mediated inflammatory diseases such as inflammatory bowel diseases (IBD). To evade expul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a06db3c726634b64000a0a47470ec5
https://eprints.gla.ac.uk/278828/1/278828.pdf
https://eprints.gla.ac.uk/278828/1/278828.pdf
Autor:
Roland Ruscher, Keith Dredge, Martha M Cooper, Ashley Van Waardenberg, Kim Miles, Alex Loukas, Matthew A. Field, Norelle L. Daly, Geraldine Buitrago, Stephanie Ryan, Darren Pickering, Paul R. Giacomin, Linda Jones, Claudia Cobos Caceres
Publikováno v:
Translational Research. 232:88-102
The symbiotic relationships shared between humans and their gastrointestinal parasites present opportunities to discover novel therapies for inflammatory diseases. A prime example of this phenomenon is the interaction of humans and roundworms such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44e9f895f8359bfebb8a4ba45f11b00
https://doi.org/10.1016/j.trsl.2021.02.012
https://doi.org/10.1016/j.trsl.2021.02.012
Autor:
Edita Ritmejerytė, Rachael Y.M. Ryan, Brendan J. Byatt, Yoshimi Peck, Karma Yeshi, Norelle L. Daly, Guangzu Zhao, Darren Crayn, Alex Loukas, Stephen G. Pyne, Roland Ruscher, Phurpa Wangchuk
Publikováno v:
Chemico-biological interactions. 368
Two new galloyl glucosides, galloyl-lawsoniaside A (4) and uromyrtoside (6), were isolated from the polar fraction of Uromyrtus metrosideros leaf extract along with another four previously identified phytochemicals (1, 2, 3, and 5). The structures of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8715c1e42e5d1b501bed06f3956828b1
https://pubmed.ncbi.nlm.nih.gov/36007634
https://pubmed.ncbi.nlm.nih.gov/36007634