Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Roland, Immler"'
Autor:
Chenxi Li, Qiongliang Liu, Lianyong Han, Haiyun Zhang, Roland Immler, Birgit Rathkolb, Judith Secklehner, Martin Hrabe deAngelis, Ali Önder Yildirim, Dagmar Zeuschner, Annette Nicke, Leo M. Carlin, Markus Sperandio, Tobias Stoeger, Markus Rehberg
Publikováno v:
Advanced Science, Vol 11, Iss 45, Pp n/a-n/a (2024)
Abstract Exposure to nanoparticles (NPs) is frequently associated with adverse cardiovascular effects. In contrast, NPs in nanomedicine hold great promise for precise lung‐specific drug delivery, especially considering the extensive pulmonary capil
Externí odkaz:
https://doaj.org/article/3af0cb7b6f5a495dae1a90d6f26d5502
Autor:
Wiebke Nadolni, Roland Immler, Kilian Hoelting, Marco Fraticelli, Myriam Ripphahn, Simone Rothmiller, Masayuki Matsushita, Ingrid Boekhoff, Thomas Gudermann, Markus Sperandio, Susanna Zierler
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
During inflammation, neutrophils are one of the first responding cells of innate immunity, contributing to a fast clearance of infection and return to homeostasis. However, excessive neutrophil infiltration accelerates unsolicited disproportionate in
Externí odkaz:
https://doaj.org/article/7c8ee04e5a11479d9b310f0f5b376134
Autor:
Roland Immler, Bärbel Lange-Sperandio, Tobias Steffen, Heike Beck, Ina Rohwedder, Jonas Roth, Matteo Napoli, Georg Hupel, Frederik Pfister, Bastian Popper, Bernd Uhl, Hanna Mannell, Christoph A. Reichel, Volker Vielhauer, Jürgen Scherberich, Markus Sperandio, Monika Pruenster
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Uromodulin (UMOD) is produced and secreted by tubular epithelial cells. Secreted UMOD polymerizes (pUMOD) in the tubular lumen, where it regulates salt transport and protects the kidney from bacteria and stone formation. Under various pathological co
Externí odkaz:
https://doaj.org/article/745309dbf1514ede9534274d726a3ede
Autor:
Ina Rohwedder, Angela R.M. Kurz, Monika Pruenster, Roland Immler, Robert Pick, Tanja Eggersmann, Sarah Klapproth, Jennifer L. Johnson, Sergi Masgrau Alsina, Clifford A. Lowell, Attila Mócsai, Sergio D. Catz, Markus Sperandio
Publikováno v:
Haematologica, Vol 105, Iss 7 (2020)
Leukocyte recruitment into inflamed tissue is highly dependent on the activation and binding of integrins to their respective ligands, followed by the induction of various signaling events within the cell referred to as outside-in signaling. Src fami
Externí odkaz:
https://doaj.org/article/fdb7b307992049d6a38bd8e080a3a16e
Autor:
Yao Ye, Aurelia Vattai, Nina Ditsch, Christina Kuhn, Martina Rahmeh, Sven Mahner, Myriam Ripphahn, Roland Immler, Markus Sperandio, Udo Jeschke, Viktoria von Schönfeldt
Publikováno v:
Endocrine Connections, Vol 7, Iss 5, Pp 749-761 (2018)
Although an inflammatory microenvironment is required for successful implantation, an inflammatory overreaction is one of the causes of unexplained recurrent pregnancy losses (uRPL). Prostaglandin E2 (PGE2) plays a pivotal role in regulating immune b
Externí odkaz:
https://doaj.org/article/13f0754948f249ef9cc156a84549265e
Autor:
Qiuyue Ma, Roland Immler, Monika Pruenster, Markus Sellmayr, Chenyu Li, Albrecht von Brunn, Brigitte von Brunn, Rosina Ehmann, Roman Wölfel, Matteo Napoli, Qiubo Li, Paola Romagnani, Ralph Thomas Böttcher, Markus Sperandio, Hans-Joachim Anders, Stefanie Steiger
Publikováno v:
Blood. 139:3402-3417
Neutrophils are key players during host defense and sterile inflammation. Neutrophil dysfunction is a characteristic feature of the acquired immunodeficiency during kidney disease. We speculated that the impaired renal clearance of the intrinsic puri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c414bac58411d11f79122e28590221d3
https://doi.org/10.1182/blood.2021011234
https://doi.org/10.1182/blood.2021011234
Autor:
Eytan R Barnea, Ina Rohwedder, Thomas Gudermann, Sergi Masgrau-Alsina, Susanna Zierler, Scott I. Simon, Anna Yevtushenko, Markus Sperandio, Oliver Soehnlein, Annika Bertsch, Roland Immler, Markus Moser, Wiebke Nadolni, Markus Rehberg, Monika Pruenster, Tobias Schroll, Vasilios A. Morikis
Publikováno v:
Cardiovasc. Res. 118, 1289–1302 (2022)
Aims Neutrophil trafficking within the vasculature strongly relies on intracellular calcium signaling. Sustained Ca2+ influx into the cell requires a compensatory efflux of potassium to maintain membrane potential. Here, we aimed to investigate wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3086c045419381c6b4e58c771708946a
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61889
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61889
Autor:
Georg Hupel, Markus Sperandio, Monika Pruenster, Volker Vielhauer, Bastian Popper, Bernd Uhl, Jürgen E. Scherberich, Roland Immler, Hanna Mannell, Tobias Steffen, Jonas Roth, Bärbel Lange-Sperandio, Christoph A. Reichel, Heike Beck, Frederik Pfister
Uromodulin (UMOD) is produced and secreted by tubular epithelial cells. Secreted UMOD polymerizes (pUMOD) within the lumen, where it regulates salt transport and protects the kidney from bacteria and stone formation. Under various pathological condit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e07096cc117a215a41b9f03fd05c78c
https://doi.org/10.1101/2020.07.18.206508
https://doi.org/10.1101/2020.07.18.206508
Autor:
Georg Kollias, Vasileia Ismini Alexaki, Aaron Hoffmann, Markus Sperandio, Sergei A. Nedospasov, Johanna Kotrba, Thomas Fischer, Roland Immler, Anne Dudeck, Konstantinos Katsoulis-Dimitriou, Stephan René Jahn, Burkhart Schraven, Triantafyllos Chavakis, Jan Dudeck, Lorena Morton, Simon Winzer, Andreas Müller, Ildiko Rita Dunay, Martin Voss
Publikováno v:
Immunity. 54(3)
Tissue resident mast cells (MCs) rapidly initiate neutrophil infiltration upon inflammatory insult, yet the molecular mechanism is still unknown. Here, we demonstrated that MC-derived tumor necrosis factor (TNF) was crucial for neutrophil extravasati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4cf972f59849e9f3e6dd6ad158bd07
https://pubmed.ncbi.nlm.nih.gov/33542498
https://pubmed.ncbi.nlm.nih.gov/33542498
Autor:
Roland Immler, Johanna Kotrba, Aaron Hoffmann, Sergei A. Nedospasov, Vasileia Ismini Alexaki, Andreas J. Mueller, Triantafyllos Chavakis, Lorena Morton, Simon Winzer, Markus Sperandio, Burkhart Schraven, Martin Voss, Ildiko Rita Dunay, Stephan René Jahn, Jan Dudeck, George Kollias, Thomas Fischer, Anne Dudeck
Publikováno v:
SSRN Electronic Journal.
Tissue resident mast cells (MCs) rapidly initiate neutrophil infiltration upon inflammatory insult, yet the molecular mechanism is still unknown. Here, we demonstrate that MC-derived TNF is crucial for neutrophil extravasation to sites of sterile ski
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bd321c90d64f3640ef92607b2158549
https://doi.org/10.2139/ssrn.3651507
https://doi.org/10.2139/ssrn.3651507