Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Roland, Hartig"'
Autor:
Ilyas Ahmad, Juliane Lokau, Birte Kespohl, Naveed Altaf Malik, Shahid Mahmood Baig, Roland Hartig, Daniel Behme, Roland Schwab, Janine Altmüller, Muhammad Jameel, Sören Mucha, Holger Thiele, Muhammad Tariq, Peter Nürnberg, Jeanette Erdmann, Christoph Garbers
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Craniosynostosis is characterized by the premature fusion and ossification of one or more of the sutures of the calvaria, often resulting in abnormal features of the face and the skull. In cases in which growth of the brain supersedes availa
Externí odkaz:
https://doaj.org/article/37abbe8ef1aa4c21a5485f639564dcf7
Publikováno v:
Genes and Diseases, Vol 10, Iss 2, Pp 373-376 (2023)
Externí odkaz:
https://doaj.org/article/4ec702fe34c847c3bb7d897919d7e45c
Autor:
Dawadschargal Dubiel, Jing Wang, Roland Hartig, Supattra Chaithongyot, Wolfgang Dubiel, Michael Naumann
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106468- (2023)
Summary: The COP9 signalosome (CSN) and cullin-RING ubiquitin ligases (CRLs) form latent CSN-CRL complexes detectable in cells. We demonstrate that the CSN variants CSNCSN7A and CSNCSN7B preferentially bind to CRL3 or CRL4A and CRL4B, respectively. I
Externí odkaz:
https://doaj.org/article/2bf6b1aa458a46609195ed2497825522
Autor:
Marion Möckel, Nino Baldok, Thorsten Walles, Roland Hartig, Andreas J. Müller, Udo Reichl, Yvonne Genzel, Heike Walles, Cornelia Wiese-Rischke
Publikováno v:
Cells, Vol 11, Iss 22, p 3634 (2022)
Our knowledge about respiratory virus spreading is mostly based on monolayer cultures that hardly reflect the complex organization of the airway epithelium. Thus, there is a strong demand for biologically relevant models. One possibility to study vir
Externí odkaz:
https://doaj.org/article/8b5232e02840462aba84b5211b34f4a1
Autor:
Annika Schultz, Marvin Schnurra, Ali El-Bizri, Nadine M. Woessner, Sara Hartmann, Roland Hartig, Susana Minguet, Burkhart Schraven, Luca Simeoni
Publikováno v:
Cells, Vol 11, Iss 17, p 2723 (2022)
Alterations in both the expression and function of the non-receptor tyrosine kinase Zap70 are associated with numerous human diseases including immunodeficiency, autoimmunity, and leukemia. Zap70 propagates the TCR signal by phosphorylating two impor
Externí odkaz:
https://doaj.org/article/db624c48de2e40a6a9e7b62f90a02226
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 14, Iss , Pp 100218- (2021)
Inflammation and alterations in essential protein structures in the brain might also change the cellular distribution in the cerebrospinal fluid (CSF).Using flow cytometry, we analyzed cell populations of the innate and adaptive immune system associa
Externí odkaz:
https://doaj.org/article/01a25e54209b4c1d8f7d27dc98c8fb54
Autor:
Matthias Kästle, Camilla Merten, Roland Hartig, Carlos Plaza-Sirvent, Ingo Schmitz, Ursula Bommhardt, Burkhart Schraven, Luca Simeoni
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7271 (2022)
Signaling via the TCR, which is initiated by the Src-family tyrosine kinase Lck, is crucial for the determination of cell fates in the thymus. Because of its pivotal role, ablation of Lck results in a profound block of T-cell development. Here, we sh
Externí odkaz:
https://doaj.org/article/551d2a0fdc9c41669a8d33a3d70f7836
Autor:
Mandy Busse, Kim-Norina Jutta Campe, Anke Redlich, Anika Oettel, Roland Hartig, Serban-Dan Costa, Ana Claudia Zenclussen
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Preterm birth (PTB) is defined as birth before 37 completed weeks of gestation. The causes of PTB are multiple and complex, the underlying pathophysiology being largely unknown. Interferences in the fine-tuned balance of the maternal immune system ha
Externí odkaz:
https://doaj.org/article/2eb2cbadcd834c03bb203d58bdc1e1d0
Autor:
Eva Meyer, Roland Hartig, Christian Mawrin, Bernhard Bogerts, Henrik Dobrowolny, Mandy Busse, Stefan Busse
Publikováno v:
GeroPsych. 35:149-155
Abstract. Because its secretion is changed in cerebrospinal fluid and peripheral blood, the neuronal polypeptide VGF (nonacronymic) has been discussed as a biomarker for neuropsychiatric disorders. We have shown an enhanced VGF expression by T-cells
Autor:
Syed Ahsan Raza, Anne Albrecht, Gürsel Çalışkan, Bettina Müller, Yunus Emre Demiray, Susann Ludewig, Susanne Meis, Nicolai Faber, Roland Hartig, Burkhart Schraven, Volkmar Lessmann, Herbert Schwegler, Oliver Stork
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Intra-hippocampal circuits are essential for associating a background context with behaviorally salient stimuli and involve cholinergic modulation at SST+ interneurons. Here the authors show that the salience of the background context memory is modul
Externí odkaz:
https://doaj.org/article/bb2ce21df8184b16927e262706f74ba5