Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Rokhaya Ndiaye"'
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Breast cancer (BC) is an increasing public health issue worldwide. BC incidence and mortality rates are rising in transitioning countries in Africa, with the most rapid increase occurring in Sub-Saharan Africa (SSA). Female BC represents 25.8% of all
Externí odkaz:
https://doaj.org/article/4e558b4c566046a4a32eed3a9f266561
Autor:
El Hadji Malick Ndour, Khuthala Mnika, Fatou Guèye Tall, Moussa Seck, Indou Dème Ly, Victoria Nembaware, Gaston Kuzamunu Mazandu, Hélène Ange Thérèse Sagna Bassène, Rokhaya Dione, Aliou Abdoulaye Ndongo, Jean Pascal Demba Diop, Nènè Oumou Kesso Barry, Moustapha Djité, Rokhaya Ndiaye Diallo, Papa Madièye Guèye, Saliou Diop, Ibrahima Diagne, Aynina Cissé, Ambroise Wonkam, Philomène Lopez Sall
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0273745 (2022)
Sickle cell anemia (SCA) is caused by a single point variation in the β-globin gene (HBB): c.20A> T (p.Glu7Val), in homozygous state. SCA is characterized by sickling of red blood cells in small blood vessels which leads to a range of multiorgan com
Externí odkaz:
https://doaj.org/article/a1627c28a3d941218b51f24597e04dc2
Autor:
Jean Pascal Demba Diop, Andréa Régina Gnilane Sène, Yacouba Dia, Seydi Abdoul Ba, Serigne Saliou Mbacke, Cheikh Ameth Tidiane Ly, Pierre Diaga Sarr, Doudou Diouf, Sidy Ka, Babacar Mbengue, Serigne Modou Kane Gueye, Pape Saloum Diop, Maguette Sylla Niang, Papa Madieye Gueye, Philomene Lopez Sall, Ahmadou Dem, Aynina Cisse, Alioune Dieye, Rokhaya Ndiaye
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Founder mutations have been reported in BRCA1 and BCRA2 in different ethnic groups with inherited breast cancer. Testing of targeted mutations in specific populations is important for cancer prevention in mutation carriers. In Sub-Saharan Africa, onl
Externí odkaz:
https://doaj.org/article/3bbd073a2a1f425abbe10b8a4c2e00ad
Autor:
Alassane Thiam, Michel Sanka, Rokhaya Ndiaye Diallo, Magali Torres, Babacar Mbengue, Nicolas Fernandez Nunez, Fatou Thiam, Gora Diop, Geneviève Victorero, Catherine Nguyen, Alioune Dieye, Pascal Rihet
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-15 (2019)
Abstract Background Plasmodium falciparum malaria remains a major health problem in Africa. The mechanisms of pathogenesis are not fully understood. Transcriptomic studies may provide new insights into molecular pathways involved in the severe form o
Externí odkaz:
https://doaj.org/article/0636424fc1f0449287ccd1404aae8889
Autor:
Jean Pascal Demba Diop, Rokhaya Ndiaye Diallo, Violaine Bourdon-Huguenin, Ahmadou Dem, Doudou Diouf, Mamadou Moustapha Dieng, Seydi Abdoul Ba, Yacouba Dia, Sidy Ka, Babacar Mbengue, Alassane Thiam, Oumar Faye, Papa Amadou Diop, Hagay Sobol, Alioune Dieye
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-7 (2019)
Abstract Background Pathogenic variants associated with hereditary breast cancer have been reported for BRCA1 and BRCA2 (BRCA1/2) genes in patients from multiple ethnicities, but limited information is available from sub-Saharan African populations.
Externí odkaz:
https://doaj.org/article/005e54af1784496ab5107c6934314197
Autor:
Yacouba Dia, Samuel Mawuli Adadey, Jean Pascal Demba Diop, Elvis Twumasi Aboagye, Seydi Abdoul Ba, Carmen De Kock, Cheikh Ahmed Tidjane Ly, Oluwafemi Gabriel Oluwale, Andrea Regina Gnilane Sène, Pierre Diaga Sarr, Bay Karim Diallo, Rokhaya Ndiaye Diallo, Ambroise Wonkam
Publikováno v:
Biology, Vol 11, Iss 5, p 795 (2022)
This study aimed to investigate GJB2 (MIM: 121011) and GJB6 (MIM: 604418) variants associated with familial non-syndromic hearing impairment (HI) in Senegal. We investigated a total of 129 affected and 143 unaffected individuals from 44 multiplex fam
Externí odkaz:
https://doaj.org/article/2d1c2feb18454af69a407c83b21b5b7b
Autor:
Gora Diop, Céline Derbois, Cheikh Loucoubar, Babacar Mbengue, Bineta Niakhana Ndao, Fatou Thiam, Alassane Thiam, Rokhaya Ndiaye, Yakhya Dieye, Robert Olaso, Jean-Francois Deleuze, Alioune Dieye
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-10 (2018)
Abstract Background Severe forms of malaria (SM) are an outcome of Plasmodium falciparum infection and can cause death especially in children under 4 years of age. RNASE3 (ECP) has been identified as an inhibitor of Plasmodium parasites growth in vit
Externí odkaz:
https://doaj.org/article/ed5cfb85490a483683c263f98fba2dbd
Autor:
Alassane Thiam, Sabrina Baaklini, Babacar Mbengue, Samia Nisar, Maryam Diarra, Sandrine Marquet, Mouhamadou Mansour Fall, Michel Sanka, Fatou Thiam, Rokhaya Ndiaye Diallo, Magali Torres, Alioune Dieye, Pascal Rihet
Publikováno v:
PeerJ, Vol 6, p e6048 (2018)
Background Host factors, including host genetic variation, have been shown to influence the outcome of Plasmodium falciparum infection. Genome-wide linkage studies have mapped mild malaria resistance genes on chromosome 6p21, whereas NCR3-412 polymor
Externí odkaz:
https://doaj.org/article/c6e14d25db7d43359fec97131f45b7ff
Autor:
Fatou Gueye Tall, Cyril Martin, El hadji Malick Ndour, Camille Faes, Indou Déme Ly, Vincent Pialoux, Philippe Connes, Papa Madieye Gueye, Rokhaya Ndiaye Diallo, Céline Renoux, Ibrahima Diagne, Pape Amadou Diop, Aynina Cissé, Philomène Lopez Sall, Philippe Joly
Publikováno v:
Antioxidants, Vol 9, Iss 9, p 863 (2020)
Oxidative stress would play a role in the pathophysiology of sickle cell anemia (SCA). We tested the impact of common SCA genetic modifiers (alpha-thalassemia, G6PD deficiency, HbF quantitative trait loci; QTL) and pro/antioxidant genes polymorphisms
Externí odkaz:
https://doaj.org/article/7d31a1249997430fb877d58cca12ad67
Autor:
Anavaj Sakuntabhai, Rokhaya Ndiaye, Isabelle Casadémont, Chayanon Peerapittayamongkol, Christophe Rogier, Patricia Tortevoye, Adama Tall, Richard Paul, Chairat Turbpaiboon, Waraphon Phimpraphi, Jean-Francois Trape, André Spiegel, Simon Heath, Odile Mercereau-Puijalon, Alioune Dieye, Cécile Julier
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e2000 (2008)
Plasmodium falciparum malaria episodes may vary considerably in their severity and clinical manifestations. There is good evidence that host genetic factors contribute to this variability. To date, most genetic studies aiming at the identification of
Externí odkaz:
https://doaj.org/article/845db98f19934ca19e02117e717be4c8