The Effect of Heat Shock on Myogenic Differentiation of Human Skeletal-Muscle-Derived Mesenchymal Stem/Stromal Cells

Autor: Rokas Mikšiūnas, Siegfried Labeit, Daiva Bironaitė

Publikováno v: Cells, Vol 11, Iss 20, p 3209 (2022)

Muscle injuries, degenerative diseases and other lesions negatively affect functioning of human skeletomuscular system and thus quality of life. Therefore, the investigation of molecular mechanisms, stimulating myogenic differentiation of primary ske

Externí odkaz: https://doaj.org/article/0d61da6c4e0746cd9b5fbd877c33ba80

The Effect of CaV1.2 Inhibitor Nifedipine on Chondrogenic Differentiation of Human Bone Marrow or Menstrual Blood-Derived Mesenchymal Stem Cells and Chondrocytes

Autor: Ilona Uzieliene, Daiva Bironaite, Rokas Miksiunas, Edvardas Bagdonas, Raminta Vaiciuleviciute, Ali Mobasheri, Eiva Bernotiene

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6730

Cartilage is an avascular tissue and sensitive to mechanical trauma and/or age-related degenerative processes leading to the development of osteoarthritis (OA). Therefore, it is important to investigate the mesenchymal cell-based chondrogenic regener

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7a7374efe71b243e1f1bb7e33e6e3c
https://doi.org/10.3390/ijms24076730

Cardiomyogenic Differentiation Potential of Human Dilated Myocardium-Derived Mesenchymal Stem/Stromal Cells: The Impact of HDAC Inhibitor SAHA and Biomimetic Matrices

Autor: Vytautas Cepla, Agne Vailionyte, Kestutis Rucinskas, Siegfried Labeit, Rokas Miksiunas, Ruta Aldonyte, Vilius Janusauskas, Daiva Bironaite, Gintare Stankeviciene, Ramunas Valiokas, Romuald Eimont, Tadas Jelinskas

Publikováno v: International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12702
International Journal of Molecular Sciences, Vol 22, Iss 12702, p 12702 (2021)
International journal of molecular sciences, Basel : MDPI, 2021, vol. 22, iss. 23, art. no.12702, p. 1-25
International Journal of Molecular Sciences

Dilated cardiomyopathy (DCM) is the most common type of nonischemic cardiomyopathy characterized by left ventricular or biventricular dilation and impaired contraction leading to heart failure and even patients’ death. Therefore, it is important to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d93c3ff8f05b55a033847c67a88d85d9

Homeobox Genes and Homeodomain Proteins: New Insights into Cardiac Development, Degeneration and Regeneration

Autor: Rokas, Miksiunas, Ali, Mobasheri, Daiva, Bironaite

Publikováno v: Advances in experimental medicine and biology. 1212

Cardiovascular diseases are the most common cause of human death in the developing world. Extensive evidence indicates that various toxic environmental factors and unhealthy lifestyle choices contribute to the risk, incidence and severity of cardiova

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::96cefd5ab6a3a4d84ca55d05e0d2776d
https://pubmed.ncbi.nlm.nih.gov/30945165

Scanning electrochemical microscopy for the investigation of redox potential of human myocardium-derived mesenchymal stem cells grown at 2D and 3D conditions

Autor: Jurate Petroniene, Inga Morkvenaite-Vilkonciene, Kestutis Rucinskas, Arunas Ramanavicius, Vilius Janusauskas, Daiva Bironaite, Almira Ramanaviciene, Rokas Miksiunas

Publikováno v: Electrochimica Acta. 360:136956

Three-dimensional (3D) cell cultivation systems in vitro are promising biomodels to study the metabolic processes of healthy and diseased human heart cells. Cardiac 3D-spheroids are mimicking cell living conditions and, therefore, they can be employe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fdf2fa9597b83690408484cc47c27e92
https://doi.org/10.1016/j.electacta.2020.136956