Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rok Gaber"'
Autor:
Tina Fink, Bojana Stevović, René Verwaal, Johannes A. Roubos, Rok Gaber, Mojca Benčina, Roman Jerala, Helena Gradišar
Publikováno v:
AMB Express, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract The clustering of biosynthetic enzymes is used in nature to channel reaction products and increase the yield of compounds produced by multiple reaction steps. The coupling of multiple enzymes has been shown to increase the biosynthetic produ
Externí odkaz:
https://doaj.org/article/eafc2fc0d72845db91f1a302bce6ded8
Publikováno v:
Sensors, Vol 13, Iss 12, Pp 16330-16346 (2013)
To effectively fight against the human immunodeficiency virus infection/ acquired immunodeficiency syndrome (HIV/AIDS) epidemic, ongoing development of novel HIV protease inhibitors is required. Inexpensive high-throughput screening assays are needed
Externí odkaz:
https://doaj.org/article/4323bef6851647b28755479129fe3123
Autor:
Katja, Glinšek, Lovro, Kramer, Aleksander, Krajnc, Eva, Kranjc, Nina, Pirher, Jaka, Marušič, Leon, Hellmann, Barbara, Podobnik, Borut, Štrukelj, David, Ausländer, Rok, Gaber
Publikováno v:
Biotechnology Journal. 17:2100499
Difficulties in obtaining and maintaining the desired level of the critical quality attributes (CQAs) of therapeutic proteins as well as the pace of the development are major challenges of current biopharmaceutical development. Therapeutic proteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0827947dcd6b168365f1a153407e6a56
https://doi.org/10.1002/biot.202100499
https://doi.org/10.1002/biot.202100499
Autor:
Bojana Stevović, Roman Jerala, Helena Gradišar, Johannes Andries Roubos, Tina Fink, Mojca Benčina, Rok Gaber, René Verwaal
Publikováno v:
AMB Express
AMB Express, Vol 10, Iss 1, Pp 1-10 (2020)
AMB Express, Vol 10, Iss 1, Pp 1-10 (2020)
The clustering of biosynthetic enzymes is used in nature to channel reaction products and increase the yield of compounds produced by multiple reaction steps. The coupling of multiple enzymes has been shown to increase the biosynthetic product yield.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af79270b2c7de199f2a096926971e363
https://doi.org/10.21203/rs.3.rs-21832/v2
https://doi.org/10.21203/rs.3.rs-21832/v2
Publikováno v:
Synthetic Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6010c56526e39bc8c48fe1507621a145
https://doi.org/10.1002/9783527688104.ch12
https://doi.org/10.1002/9783527688104.ch12
Autor:
Rok Gaber, Andreja Majerle, Roman Jerala, Andrej Dobnikar, Mojca Benčina, Tina Lebar, Branko Šter
Publikováno v:
Nature Chemical Biology. 10:203-208
Electronic computer circuits consisting of a large number of connected logic gates of the same type, such as NOR, can be easily fabricated and can implement any logic function. In contrast, designed genetic circuits must employ orthogonal information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfbc21a52cf787c7864310936163e76d
https://doi.org/10.1038/nchembio.1433
https://doi.org/10.1038/nchembio.1433
Publikováno v:
Sensors, Vol 13, Iss 12, Pp 16330-16346 (2013)
Sensors (Basel, Switzerland)
Sensors
Volume 13
Issue 12
Pages: 16330-16346
Scopus-Elsevier
Sensors (Basel, Switzerland)
Sensors
Volume 13
Issue 12
Pages: 16330-16346
Scopus-Elsevier
To effectively fight against the human immunodeficiency virus infection/ acquired immunodeficiency syndrome (HIV/AIDS) epidemic, ongoing development of novel HIV protease inhibitors is required. Inexpensive high-throughput screening assays are needed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057097b4f6442514b33b1d7fce60b68f
http://www.mdpi.com/1424-8220/13/12/16330
http://www.mdpi.com/1424-8220/13/12/16330
Publikováno v:
ACS Synthetic Biology
The high mutation rate of the human immunodeficiency virus type 1 (HIV-1) virus is a major problem since it evades the function of antibodies and chemical inhibitors. Here, we demonstrate a viral detection strategy based on synthetic biology principl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c201b405a912b4a7556004ef696829bc
https://pubmed.ncbi.nlm.nih.gov/25393958
https://pubmed.ncbi.nlm.nih.gov/25393958
Autor:
Boštjan Pirš, Andreja Majerle, Anja Golob, Miha Jerala, Vida Forstnerič, Lucija Kadunc, Dušan Vučko, Rok Gaber, Jan Lonzarić, Urban Bezeljak, Mojca Benčina, Tina Lebar, Anže Smole, Alja Oblak, Roman Jerala, Martin Stražar, Uroš Zupančič
Publikováno v:
Nature Communications. 5
Bistable switches are fundamental regulatory elements of complex systems, ranging from electronics to living cells. Designed genetic toggle switches have been constructed from pairs of natural transcriptional repressors wired to inhibit one another.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97b560cbb02bbc97a8bf213519cf3c1
https://doi.org/10.1038/ncomms6007
https://doi.org/10.1038/ncomms6007
Autor:
Jerneja Mori, Irena Vovk, Roman Jerala, Gregor Anderluh, Nejc Tomšic, Susan Chen, Monika Avbelj, Matthew P. DeLisa, Rok Gaber, Vesna Hodnik, Mojca Benčina, Gabriel C. Wu, Tina Lebar, John E. Dueber, Vesna Glavnik, Tomaž Koprivnjak, Hansen Xu, Robert J. Conrado, Jernej Turnšek, Jason T. Boock
Publikováno v:
Nucleic Acids Research
Synthetic scaffolds that permit spatial and temporal organization of enzymes in living cells are a promising post-translational strategy for controlling the flow of information in both metabolic and signaling pathways. Here, we describe the use of pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c86feacf0f9f6738190e4b63bd34fc2
https://pubmed.ncbi.nlm.nih.gov/22021385
https://pubmed.ncbi.nlm.nih.gov/22021385