Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Roisin M Dwyer"'
Autor:
Peadar S Waters, Roisin M Dwyer, Cathy Brougham, Claire L Glynn, Deirdre Wall, Peter Hyland, Maria Duignan, Mark McLoughlin, John Newell, Michael J Kerin
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90605 (2014)
While a range of miRNAs have been shown to be dysregulated in the circulation of patients with breast cancer, little is known about the relationship between circulating levels and tumour characteristics. The aim of this study was to analyse alteratio
Externí odkaz:
https://doaj.org/article/6f840e8515344325a87b22539fa98006
Autor:
Sonja Khan, Cathy L Brougham, James Ryan, Arisha Sahrudin, Gregory O'Neill, Deirdre Wall, Catherine Curran, John Newell, Michael J Kerin, Roisin M Dwyer
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68753 (2013)
MicroRNAs are small non-coding RNA molecules that control gene expression post-transcriptionally, and are known to be altered in many diseases including breast cancer. The aim of this study was to determine the relevance of miR-379 in breast cancer.
Externí odkaz:
https://doaj.org/article/07c15205b97842b8a2579564e78c2490
Autor:
Peadar S Waters, Ailbhe M McDermott, Deirdre Wall, Helen M Heneghan, Nicola Miller, John Newell, Michael J Kerin, Roisin M Dwyer
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50459 (2012)
MiRNAs are key regulators of tumorigenesis that are aberrantly expressed in the circulation and tissue of patients with cancer. The aim of this study was to determine whether miRNA dysregulation in the circulation reflected similar changes in tumour
Externí odkaz:
https://doaj.org/article/952c92e5ad004dd6869b0e7898b487b5
Autor:
James Ryan, Catherine E Curran, Emer Hennessy, John Newell, John C Morris, Michael J Kerin, Roisin M Dwyer
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16023 (2011)
INTRODUCTION: The presence, relevance and regulation of the Sodium Iodide Symporter (NIS) in human mammary tissue remains poorly understood. This study aimed to quantify relative expression of NIS and putative regulators in human breast tissue, with
Externí odkaz:
https://doaj.org/article/b64f700f466d4140a41f13107e4e83cc
Targeting stromal cell Syndecan‐2 reduces breast tumour growth, metastasis and limits immune evasion
Autor:
Stephen J. Elliman, Eva Camarillo‐Retamosa, Luke Watson, Lisa O'Flynn, Roisin M. Dwyer, Timothy O'Brien, Laura Deedigan, Laura R. Barkley, Matthew D. Griffin, Michael J. Kerin, Senthilkumar Alagesan, Paul Loftus
Publikováno v:
International Journal of Cancer
Tumour stromal cells support tumourigenesis. We report that Syndecan‐2 (SDC2) is expressed on a nonepithelial, nonhaematopoietic, nonendothelial stromal cell population within breast cancer tissue. In vitro, syndecan‐2 modulated TGFβ signalling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20ce9046963b432b316091c538dff2e
http://europepmc.org/articles/PMC7839764
http://europepmc.org/articles/PMC7839764
Autor:
Aoife Lowery, Roisin M. Dwyer, Michael J. Kerin, Niall M. McInerney, Ritihaas Surya Challapalli
Publikováno v:
Stem Cell Reviews and Reports. 17:523-538
Tissue engineering using Adipose Derived Stromal Cells (ADSCs) has emerged as a novel regenerative medicine approach to replace and reconstruct soft tissue damaged or lost as a result of disease process or therapeutic surgical resection. ADSCs are an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b096004efc599920c88b6d91784cc855
https://doi.org/10.1007/s12015-020-10038-1
https://doi.org/10.1007/s12015-020-10038-1
Publikováno v:
Nanoscale Advances
Approximately 90% of cancers have their origins in epithelial tissues and this leads to epithelial thickening, but the ultrastructural changes and underlying architecture is less well known. Depth resolved label free visualization of nanoscale tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e79057c894eed265480f89a43c40870
https://doi.org/10.1039/d0na00371a
https://doi.org/10.1039/d0na00371a
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdbe6f0e007f183353174a32e35c57f8
https://doi.org/10.2139/ssrn.4023082
https://doi.org/10.2139/ssrn.4023082
Publikováno v:
Bone Reports. 17:101597
Cancer cells favour migration and metastasis to bone tissue for 70-80 % of advanced breast cancer patients and it has been proposed that bone tissue provides attractive physical properties that facilitate tumour invasion, resulting in osteolytic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039fd60f3f40a5088d80b34356311e19
https://doi.org/10.1016/j.bonr.2022.101597
https://doi.org/10.1016/j.bonr.2022.101597
Autor:
Roisin M. Dwyer, Elan C. McCarthy
Publikováno v:
Biomedicines, Vol 9, Iss 827, p 827 (2021)
Biomedicines
Biomedicines
Many microRNAs exist in clusters that share comparable sequence homology and may target genes in a common pathway. The miR-379/miR-656 (C14MC) cluster is imprinted in the DLK1-Dio3 region of 14q32.3 and contains 42 miRNAs. It plays a functional role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8a16ef8feeff2196240f023b225eac
https://www.mdpi.com/2227-9059/9/7/827
https://www.mdpi.com/2227-9059/9/7/827