Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Roi Strulovich"'
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Chloride intracellular channels (CLICs) are a family of unique proteins, that were suggested to adopt both soluble and membrane-associated forms. Moreover, following this unusual metamorphic change, CLICs were shown to incorporate into membr
Externí odkaz:
https://doaj.org/article/d8813ac4fc1b461b81311090de4a4bce
Autor:
Moshe Giladi, Su Youn Lee, Yarden Ariely, Yotam Teldan, Rotem Granit, Roi Strulovich, Yoni Haitin, Ka Young Chung, Daniel Khananshvili
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Mammalian Na+/Ca2+ exchangers, NCX1 and NCX3, generate splice variants, whereas NCX2 does not. The CBD1 and CBD2 domains form a regulatory tandem (CBD12), where Ca2+ binding to CBD1 activates and Ca2+ binding to CBD2 (bearing the splicing se
Externí odkaz:
https://doaj.org/article/e36e68f88afb4f2581ecb244352f12a3
Publikováno v:
Biochemistry. 55:5353-5365
The Kv7 (KCNQ) channel family, comprising voltage-gated potassium channels, plays major roles in fine-tuning cellular excitability by reducing firing frequency and controlling repolarization. Kv7 channels have a unique intracellular C-terminal (CT) d
Autor:
Reuven Wiener, Bayan Mashahreh, Roi Strulovich, Yoni Haitin, Fouad Hassouna, Nadine Soudah, Einav Cohen-Kfir
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32(5)
All ubiquitin-like proteins (UBLs) undergo an activation process before their conjugation to target proteins. Although the steps required for the activation of UBLs are conserved and common to all UBLs, we have previously shown that the activation of
Autor:
Ilan, Edri, Michal, Goldenberg, Michal, Lisnyansky, Roi, Strulovich, Hadas, Newman, Anat, Loewenstein, Daniel, Khananshvili, Moshe, Giladi, Yoni, Haitin
Publikováno v:
Journal of visualized experiments : JoVE. (126)
Prenyltransferases (PT) are a group of enzymes that catalyze chain elongation of allylic diphosphate using isopentenyl diphosphate (IPP) via multiple condensation reactions. DHDDS (dehydrodolichyl diphosphate synthase) is a eukaryotic long-chain cis-
Autor:
Yoni Haitin, Moshe Giladi, Daniel Khananshvili, Anat Loewenstein, Hadas Newman, Roi Strulovich, Michal Lisnyansky, Michal Goldenberg, Ilan Edri
Publikováno v:
Journal of Visualized Experiments.
Autor:
Asher Peretz, Dmitri I. Svergun, Bernard Attali, Giancarlo Tria, William Sam Tobelaim, Roi Strulovich, Meidan Dvir, Olaf Pongs, Joel A. Hirsch, Dana Sachyani
Publikováno v:
Structure 22(11), 1582-1594 (2014). doi:10.1016/j.str.2014.07.016
SummaryKv7 channels tune neuronal and cardiomyocyte excitability. In addition to the channel membrane domain, they also have a unique intracellular C-terminal (CT) domain, bound constitutively to calmodulin (CaM). This CT domain regulates gating and
Autor:
Daniel Khananshvili, Roi Strulovich, Ilan Edri, Hadas Newman, Yoni Haitin, Moshe Giladi, Anat Loewenstein, Michal Goldenberg
Publikováno v:
Protein expression and purification. 132
Protein asparagine (N)-linked glycosylation is a post-translational modification that occurs in the endoplasmic reticulum; it plays an important role in protein folding, oligomerization, quality control, sorting, and transport. Accordingly, disorders
Autor:
Dafna Greitzer-Antes, Roi Strulovich, Adi Etzioni, Joel A. Hirsch, Sivan Siloni, Dodo Chikvashvilli, Dana Sachyani, Noa Regev, Ilana Lotan
Publikováno v:
The Journal of Neuroscience. 31:14158-14171
Whereas neuronal M-type K+channels composed of KCNQ2 and KCNQ3 subunits regulate firing properties of neurons, presynaptic KCNQ2 subunits were demonstrated to regulate neurotransmitter release by directly influencing presynaptic function. Two interac
Publikováno v:
'Scientific Reports ', vol: 8, pages: 6882-1-6882-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Chloride intracellular channels (CLICs) are a family of unique proteins, that were suggested to adopt both soluble and membrane-associated forms. Moreover, following this unusual metamorphic change, CLICs were shown to incorporate into membranes and