Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Rohit Shukla"'
Autor:
Rohit Shukla, Anshuman Chandra, Anuj Kumar, Pallavi Kandpal, Himanshu Avashthi, Vijay Kumar Goel, Imteyaz Qamar, Nagendra Singh, David J. Kelvin, Tiratha Raj Singh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract In recent years, the outbreak of infectious disease caused by Zika Virus (ZIKV) has posed a major threat to global public health, calling for the development of therapeutics to treat ZIKV disease. Several possible druggable targets involved
Externí odkaz:
https://doaj.org/article/d9228957d8ee4565a4cf098b85e2c47a
Autor:
Sidharth Saxena, T. P. Krishna Murthy, C. R. Chandrashekhar, Lavan S. Patil, Abhinav Aditya, Rohit Shukla, Arvind Kumar Yadav, Tiratha Raj Singh, Mahesh Samantaray, Amutha Ramaswamy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-21 (2022)
Abstract Polymorphisms of Thiopurine S-methyltransferase (TPMT) are known to be associated with leukemia, inflammatory bowel diseases, and more. The objective of the present study was to identify novel deleterious missense SNPs of TPMT through a comp
Externí odkaz:
https://doaj.org/article/16ac48616fa243d5bd4bed1b4101570e
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
Alzheimer’s disease (AD) is a neurological disorder caused by the abnormal accumulation of hyperphosphorylated proteins. Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a dual phosphorylation enzyme which phosphorylates th
Externí odkaz:
https://doaj.org/article/88c58c8eeaaa4f9f9d26af6de2a79d44
Autor:
Rohit Shukla, Tiratha Raj Singh
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Alzheimer’s disease is a leading neurodegenerative disease worldwide and is the 6th leading cause of death in the USA. AD is a very complex disease and the drugs available in the market cannot fully cure it. The glycogen synthas
Externí odkaz:
https://doaj.org/article/59f93ff8f34e4337a9f0ab9f2e097664
Autor:
Tripti Pandey, Arpita Ghosh, Vivek N. Todur, Vijayakumar Rajendran, Parismita Kalita, Jupitara Kalita, Rohit Shukla, Purna B. Chetri, Harish Shukla, Amit Sonkar, Denzelle Lee Lyngdoh, Radhika Singh, Heena Khan, Joplin Nongkhlaw, Kanhu Charan Das, Timir Tripathi
Publikováno v:
ACS Omega, Vol 5, Iss 19, Pp 11084-11091 (2020)
Externí odkaz:
https://doaj.org/article/6bdac52b8d694b5daad2ac8feb12cb46
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101992- (2021)
Summary: The use of remdesivir to treat COVID-19 will likely continue before clinical trials are completed. Due to the lengthening pandemic and evolving nature of the virus, predicting potential residues prone to mutation is crucial for the managemen
Externí odkaz:
https://doaj.org/article/027a8961b2bc40aca84110aa7dbc9e94
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Isocitrate lyase (ICL), a potential anti-tubercular drug target, catalyzes the first step of the glyoxylate shunt. In the present investigation, we studied the conformational flexibility of MtbICL to better understand its stability and catal
Externí odkaz:
https://doaj.org/article/b886f7c010434bc289f4df6ea8facbd5
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
In this work, we perform analysis of detection and counting of cars using a low-power IBM TrueNorth Neurosynaptic System. For our evaluation we looked at a publicly-available dataset that has overhead imagery of cars with context present in the image
Externí odkaz:
https://doaj.org/article/ae728c1afea84f17bf0e6875397b2a2d
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Emerging neural hardware substrates, such as IBM's TrueNorth Neurosynaptic System, can provide an appealing platform for deploying numerical algorithms. For example, a recurrent Hopfield neural network can be used to find the Moore-Penrose generalize
Externí odkaz:
https://doaj.org/article/2e3b4a7ad059411fa063bfba64bb8934
Publikováno v:
Frontiers in Plant Science, Vol 8 (2017)
Alternaria brassicae and Alternaria brassicicola are two major phytopathogenic fungi which cause Alternaria blight, a recalcitrant disease on Brassica crops throughout the world, which is highly destructive and responsible for significant yield losse
Externí odkaz:
https://doaj.org/article/a9089222a5bd4d479d4fd2a3261cbda3