Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rohit Kholiya"'
Autor:
Woori Kim, Mohit Tripathi, Chunhyung Kim, Satyapavan Vardhineni, Young Cha, Shamseer Kulangara Kandi, Melissa Feitosa, Rohit Kholiya, Eric Sah, Anuj Thakur, Yehan Kim, Sanghyeok Ko, Kaiya Bhatia, Sunny Manohar, Young-Bin Kong, Gagandeep Sindhu, Yoon-Seong Kim, Bruce Cohen, Diwan S. Rawat, Kwang-Soo Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The nuclear receptor, Nurr1, is critical for both the development and maintenance of midbrain dopamine neurons, representing a promising molecular target for Parkinson’s disease (PD). We previously identified three Nurr1 agonists (amodiaqu
Externí odkaz:
https://doaj.org/article/b81b0d3dcdc14cc4b8e8e7f126ca1dbb
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 36
A series of 2,5-disubstituted benzimidazole derivatives was synthesized with the aim to identify compounds with potent anti-TB activity. All the compounds were screened in vitro against cultured Mycobacterium tuberculosis H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6e8807ae2ee546fc7abe7c1bde0eb4
https://doi.org/10.1002/jbt.23123
https://doi.org/10.1002/jbt.23123
Autor:
Rohit Kholiya, Deepak Kumar, Aparna Bahuguna, Diwan S. Rawat, Shabana I. Khan, Shiv Shyam Maurya
Publikováno v:
European Journal of Medicinal Chemistry. 162:277-289
A series of novel molecular hybrids based on 4-aminoquinoline-pyrimidine were synthesized and examined for their antimalarial activity. Most of the compounds were found to have potent in vitro antimalarial activity against both CQ-sensitive D6 and CQ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7302e022c2d6fb6352d220964c599e4e
https://doi.org/10.1016/j.ejmech.2018.11.021
https://doi.org/10.1016/j.ejmech.2018.11.021
Publikováno v:
ChemistrySelect. 2:9074-9083
A series of antimalarial 4-aminoquinoline-pyrimidine hybrids incorporating modified anilines at the pyrimidine end was designed and synthesized through a facile synthetic route. The present hybrids displayed excellent equipotent in vitro antiplasmodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5315fc0dfa6e997d32c090a321d050a0
https://doi.org/10.1002/slct.201701558
https://doi.org/10.1002/slct.201701558
Publikováno v:
Tetrahedron Letters. 56:1790-1793
Tetrabutylammonium glycinate [TBA][Gly] ionic liquid was found to be an efficient recyclable and biodegradable organocatalyst for selective synthesis of 3-substituted indoles and indolyl-4H-chromenes. The reaction between substituted aliphatic/aromat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a64fdc3c69efd92dc93eaf7d0db80f17
https://doi.org/10.1016/j.tetlet.2015.02.058
https://doi.org/10.1016/j.tetlet.2015.02.058
Publikováno v:
European journal of medicinal chemistry. 131
A series of 4-aminoquinoline-piperonyl-pyrimidine hybrids were synthesized with the aim of identifying compounds with enhanced antimalarial activity. All the synthesized molecules were evaluated in vitro against cultured Plasmodium falciparum W2 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12641ebc42d208c38b65032720df3c69
https://pubmed.ncbi.nlm.nih.gov/28315598
https://pubmed.ncbi.nlm.nih.gov/28315598
Publikováno v:
ChemInform. 46
Tetrabutylammonium glycinate [TBA][Gly] ionic liquid was found to be an efficient recyclable and biodegradable organocatalyst for selective synthesis of 3-substituted indoles and indolyl-4H-chromenes. The reaction between substituted aliphatic/aromat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe1d81fd609c125857445669839d7564
https://doi.org/10.1002/chin.201531078
https://doi.org/10.1002/chin.201531078
Publikováno v:
ChemInform. 45
A facile protocol, using ethylene glycol as a recyclable promoting medium for the three component reaction of indoles, aldehydes, and amines to form 3-aminoalkylated indoles, is developed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91e31deb8fcd667d24df6d9dc6f07095
https://doi.org/10.1002/chin.201442132
https://doi.org/10.1002/chin.201442132