Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rohit Aita"'
Autor:
Lei Chen, Shirley Luo, Abigail Dupre, Roshan P. Vasoya, Aditya Parthasarathy, Rohit Aita, Raj Malhotra, Joseph Hur, Natalie H. Toke, Eric Chiles, Min Yang, Weihuan Cao, Juan Flores, Christopher E. Ellison, Nan Gao, Amrik Sahota, Xiaoyang Su, Edward M. Bonder, Michael P. Verzi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Brush border gene regulation in various different tissues is incompletely understood. Here, the authors show HNF4 regulates the brush border gene program in multiple organs, such as intestine, kidney and yolk sac, and also intestinal chromatin loopin
Externí odkaz:
https://doaj.org/article/5b2c764533374b2391e6fb24a9437a11
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248691 (2021)
This study aims to document the dual mode of pharmacological action of moringa isothiocyanate-1 (MIC-1) derived from seeds of Moringa oleifera Lam. Oral administration of chemically stable MIC-1 (80 mg/kg) significantly reduced the expression of infl
Externí odkaz:
https://doaj.org/article/e68835a7420d42aeb2b84afb0938afd8
Autor:
Lea Ann Chen, Minsuk Kim, Dalin Li, Rohit Aita, Susan Cataldo, Arielle Radin, Jessica Baylor, Lily Deng, Brett Hahn, Kevin Wong, Kevin Tin, Emebet Mengesha, Dermot McGovern
Publikováno v:
Gastroenterology. 164:S50-S51
BACKGROUND The study of multiplex Crohn’s disease (CD) families has played a critical role in our understanding of the disease, including the identification of the first recognized CD risk variants in NOD2, which remain among the highest impact gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829694fb7b483aad6260c3e5d76829bd
https://doi.org/10.1053/j.gastro.2023.03.093
https://doi.org/10.1053/j.gastro.2023.03.093
Autor:
Rohit, Aita, Dennis, Aldea, Sohaib, Hassan, Joseph, Hur, Oscar, Pellon-Cardenas, Evan, Cohen, Lei, Chen, Noah, Shroyer, Sylvia, Christakos, Michael P, Verzi, James C, Fleet
Publikováno v:
The Journal of biological chemistry. 298(8)
1,25-dihydroxyvitamin D (VD) regulates intestinal calcium absorption in the small intestine (SI) and also reduces risk of colonic inflammation and cancer. However, the intestine compartment-specific target genes of VD signaling are unknown. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af8c4ebd16fd6ac49bb8d4c088048378
https://pubmed.ncbi.nlm.nih.gov/35779631
https://pubmed.ncbi.nlm.nih.gov/35779631
Autor:
Oscar Pellon-Cardenas, Lei Chen, Rohit Aita, Michael P. Verzi, Sohaib Hassan, Dennis A. Aldea, Evan S. Cohen, Joseph Hur
Publikováno v:
Aresty Rutgers Undergraduate Research Journal. 1
Vitamin D receptor (VDR) is a transcription factor that mediates calcium absorption by intestinal epithelial cells. Although calcium absorption is ca-nonically thought to occur only in the small intestine, recent studies have shown that VDR activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3a5a4e9ae603f1dd1f94f03a4afa647
https://doi.org/10.14713/arestyrurj.v1i3.175
https://doi.org/10.14713/arestyrurj.v1i3.175
Autor:
Weihuan Cao, Joseph Hur, Christopher E. Ellison, Raj Malhotra, Roshan P. Vasoya, Abigail Dupre, Min Yang, Juan Flores, Michael P. Verzi, Amrik Sahota, Aditya Parthasarathy, Lei Chen, Eric Chiles, Rohit Aita, Nan Gao, Natalie H. Toke, Shirley Luo, Edward M. Bonder, Xiaoyang Su
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
The brush border is comprised of microvilli surface protrusions on the apical surface of epithelia. This specialized structure greatly increases absorptive surface area and plays crucial roles in human health. However, transcriptional regulatory netw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb940e7c0fc3f01e7717347f0777ad96
https://doi.org/10.1038/s41467-021-22761-5
https://doi.org/10.1038/s41467-021-22761-5
Autor:
Geert Carmeliet, Patricia Soteropoulos, Steven Hutchens, Oscar Pellon-Cardenas, James C. Fleet, Noah F. Shroyer, Shanshan Li, Joseph Hur, Zachary K. Criss, Seema Husain, Rohit Aita, Sylvia Christakos, Somshuvra Mukhopadhyay, Michael P. Verzi, Puneet Dhawan, Lieve Verlinden, Jessica De La Cruz
Although vitamin D is critical for the function of the intestine, most studies have focused on the duodenum. We show that transgenic expression of the vitamin D receptor (VDR) only in the distal intestine of VDR null mice (KO/TG mice) results in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f87e70cbcaee415949ff02685424d5
https://lirias.kuleuven.be/handle/123456789/663431
https://lirias.kuleuven.be/handle/123456789/663431
Autor:
Shanshan, Li, Jessica, De La Cruz, Steven, Hutchens, Somshuvra, Mukhopadhyay, Zachary K, Criss, Rohit, Aita, Oscar, Pellon-Cardenas, Joseph, Hur, Patricia, Soteropoulos, Seema, Husain, Puneet, Dhawan, Lieve, Verlinden, Geert, Carmeliet, James C, Fleet, Noah F, Shroyer, Michael P, Verzi, Sylvia, Christakos
Publikováno v:
Mol Cell Biol
Although vitamin D is critical for the function of the intestine, most studies have focused on the duodenum. We show that transgenic expression of the vitamin D receptor (VDR) only in the distal intestine of VDR null mice (KO/TG mice) results in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fedaf8b3986d18751dde5eeb60a7eb4
https://pubmed.ncbi.nlm.nih.gov/33139494
https://pubmed.ncbi.nlm.nih.gov/33139494
Autor:
Rohit Aita, Taha Keskin, Brian Hsia, Lily Kwak, Sammy Wu, Sunit Jariwala, Denisa Ferastraoarou, Wenzhu B. Mowrey, David L. Rosenstreich
Publikováno v:
The Journal of asthma : official journal of the Association for the Care of Asthma. 58(6)
Objective: We sought to compare the impact of ASTHMAXcel, a novel, guideline-based, patient-facing mobile app to human-delivered asthma education.Methods: We conducted a focus group with asthma pat...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85dbd4daee9f20e075e32ea6f7964e75
https://pubmed.ncbi.nlm.nih.gov/32046564
https://pubmed.ncbi.nlm.nih.gov/32046564
Autor:
Christopher E. Ellison, Michael P. Verzi, Weihuan Cao, Edward M. Bonder, Dennis A. Aldea, Juan Flores, Lei Chen, Rohit Aita, Nan Gao
Publikováno v:
Cell reports
SUMMARY Cells in renewing tissues exhibit dramatic transcriptional changes as they differentiate. The contribution of chromatin looping to tissue renewal is incompletely understood. Enhancer-promoter interactions could be relatively stable as cells t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9279cb47bfc29a2df7ea1a0cfd528f28
https://doi.org/10.1016/j.celrep.2020.108679
https://doi.org/10.1016/j.celrep.2020.108679