A genome-wide association study identifies six novel risk loci for primary biliary cholangitis

Autor: Fang Qiu, Ruqi Tang, Xianbo Zuo, Xingjuan Shi, Yiran Wei, Xiaodong Zheng, Yaping Dai, Yuhua Gong, Lan Wang, Ping Xu, Xiang Zhu, Jian Wu, Chongxu Han, Yueqiu Gao, Kui Zhang, Yuzhang Jiang, Jianbo Zhou, Youlin Shao, Zhigang Hu, Ye Tian, Haiyan Zhang, Na Dai, Lei Liu, Xudong Wu, Weifeng Zhao, Xiaomin Zhang, Zhidong Zang, Jinshan Nie, Weihao Sun, Yi Zhao, Yuan Mao, Po Jiang, Hualiang Ji, Qing Dong, Junming Li, Zhenzhong Li, Xinli Bai, Li Li, Maosong Lin, Ming Dong, Jinxin Li, Ping Zhu, Chan Wang, Yanqiu Zhang, Peng Jiang, Yujue Wang, Rohil Jawed, Jing Xu, Yu Zhang, Qixia Wang, Yue Yang, Fan Yang, Min Lian, Xiang Jiang, Xiao Xiao, Yanmei Li, Jingyuan Fang, Dekai Qiu, Zhen Zhu, Hong Qiu, Jianqiong Zhang, Wenyan Tian, Sufang Chen, Ling Jiang, Bing Ji, Ping Li, Guochang Chen, Tianxue Wu, Yan Sun, Jianjiang Yu, Huijun Tang, Michun He, Min Xia, Hao Pei, Lihua Huang, Zhuye Qing, Jianfang Wu, Qinghai Huang, Junhai Han, Wei Xie, Zhongsheng Sun, Jian Guo, Gengsheng He, M. Eric Gershwin, Zhexiong Lian, Xiang Liu, Michael F. Seldin, Xiangdong Liu, Weichang Chen, Xiong Ma

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)

Primary biliary cholangitis is an autoimmune liver disease. Here, the authors show that variants in interleukin genes which potentially deregulate their expression are associated with this condition, and suggest that the IL21 signalling pathway may h

Externí odkaz: https://doaj.org/article/2d9f1e41b1654d168ba642000f183a48

Clear Discrimination of Single-Molecule of a Single-Stranded DNA Homopolymers and Hetero-Homopolymers Through a New Mutant of Mycobacterium smegmatis Porin A, MspA

Autor: Libo Zhu, Huma Bhatti, Quanjun Liu, Irshad Ali, Hang Liu, Rohil Jawed

Publikováno v: Nanoscience and Nanotechnology Letters. 11:1104-1115

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1866f3c472f8de8b5033c0d6c1e0113e
https://doi.org/10.1166/nnl.2019.2984

Replication study and meta-analysis indicate a suggestive association of RUNX3 locus with primary biliary cholangitis

Autor: Xingjuan Shi, Peng Jiang, Weichang Chen, Qiuyuan Wu, Michael F. Seldin, Chan Wang, Ye Tian, Li Li, Mingming Zhang, Rohil Jawed, M. Eric Gershwin, Xiangdong Liu, Zhe-Xiong Lian, Xiong Ma, Shu Han Yang

Publikováno v: Immunogenetics. 72(9-10)

Susceptibility to primary biliary cholangitis (PBC) is in part genetically determined. In our previous PBC genome-wide association study (GWAS) in 1118 Han Chinese PBC and 4036 controls, we noted that multiple SNPs in the runt-related transcription f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c88f9daa9d11ba8e704d38625973ac3
https://pubmed.ncbi.nlm.nih.gov/33284381

A genome-wide association study identifies six novel risk loci for primary biliary cholangitis

Autor: Xiang Zhu, Qixia Wang, Yueqiu Gao, Min Xia, Michun He, Yiran Wei, Ping Zhu, Gengsheng He, Rohil Jawed, Min Lian, Yujue Wang, Ping Xu, Zhen Zhu, Jianbo Zhou, Bing Ji, Qinghai Huang, Ruqi Tang, Lihua Huang, Yue Yang, Zhexiong Lian, Peng Jiang, Zhigang Hu, Jian Wu, Yaping Dai, Yanmei Li, M. Eric Gershwin, Hao Pei, Ling Jiang, Wei Xie, Ping Li, Michael F. Seldin, Qing Dong, Weifeng Zhao, Po Jiang, Dekai Qiu, Lan Wang, Xiang Jiang, Jianqiong Zhang, Tianxue Wu, Ye Tian, Xinli Bai, Sufang Chen, Yuhua Gong, Kui Zhang, Yanqiu Zhang, Xiao Xiao, Zhidong Zang, Fan Yang, Huijun Tang, Youlin Shao, Jing-Yuan Fang, Xiong Ma, Xudong Wu, Zhenzhong Li, Xiaomin Zhang, Haiyan Zhang, Zhong Sheng Sun, Weichang Chen, Junming Li, Yuan Mao, Hong Qiu, Yan Sun, Yuzhang Jiang, Chongxu Han, Xingjuan Shi, Wenyan Tian, Hualiang Ji, Maosong Lin, Jianfang Wu, Yu Zhang, Chan Wang, Yi Zhao, Lei Liu, Xianbo Zuo, Ming Dong, Jing Xu, Weihao Sun, Fang Qiu, Na Dai, Xiaodong Zheng, Jianjiang Yu, Jinxin Li, Li Li, Zhuye Qing, Xiang Liu, Guochang Chen, Xiangdong Liu, Jian Guo, Junhai Han, Jinshan Nie

Publikováno v: Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)

Primary biliary cholangitis (PBC) is an autoimmune liver disease with a strong hereditary component. Here, we report a genome-wide association study that included 1,122 PBC cases and 4,036 controls of Han Chinese descent, with subsequent replication

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19ef7643fd09e93ce1cdb07cb2242e8
https://pubmed.ncbi.nlm.nih.gov/28425483