Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rohan Sridhar"'
Publikováno v:
International Conference on Future of Education.
Autor:
Laurence J. Miller, Patrick M. Sexton, John Simms, Kevin J. Smith, Juan Carlos Mobarec, Emilia Elizabeth Savage, Mengjie Liu, Philip E. Thompson, Denise Wootten, Arthur Christopoulos, Rohan Sridhar, Sebastian G.B. Furness, Christopher A. Reynolds, Cassandra Koole, Kavita Pabreja
Publikováno v:
Cell
Summary Ligand-directed signal bias offers opportunities for sculpting molecular events, with the promise of better, safer therapeutics. Critical to the exploitation of signal bias is an understanding of the molecular events coupling ligand binding t
Autor:
Owen L. Woodman, Rohan Sridhar, Denise Wootten, John Simms, Celine Valant, Roger J. Summers, Arthur Christopoulos, Patrick M. Sexton, Cassandra Koole, Laurence J. Miller
Publikováno v:
Molecular Pharmacology. 78:456-465
The glucagon-like peptide-1 (GLP-1) receptor is a key regulator of insulin secretion and a major therapeutic target for treatment of diabetes. However, GLP-1 receptor function is complex, with multiple endogenous peptides that can interact with the r