Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Rohan Shad"'
Autor:
Rohan Shad, Nicolas Quach, Robyn Fong, Patpilai Kasinpila, Cayley Bowles, Miguel Castro, Ashrith Guha, Erik E. Suarez, Stefan Jovinge, Sangjin Lee, Theodore Boeve, Myriam Amsallem, Xiu Tang, Francois Haddad, Yasuhiro Shudo, Y. Joseph Woo, Jeffrey Teuteberg, John P. Cunningham, Curtis P. Langlotz, William Hiesinger
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
The echocardiogram allows for a comprehensive assessment of the cardiac musculature and valves, but its rich temporally resolved data remain underutilized. Here, the authors develop a video AI system trained to predict post-operative right ventricula
Externí odkaz:
https://doaj.org/article/b505d01868f146ffbab6d3814a231757
Autor:
Rohan Shad, MD, William Hiesinger, MD
Publikováno v:
JTCVS Open, Vol 8, Iss , Pp 412-413 (2021)
Externí odkaz:
https://doaj.org/article/6c9a97007e5d473589df159b0323d144
Autor:
Albert J. Pedroza, Alex R. Dalal, Rohan Shad, Nobu Yokoyama, Ken Nakamura, Olivia Mitchel, Casey Gilles, William Hiesinger, Michael P. Fischbein
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:971-978
Background: Smooth muscle cell (SMC) phenotypic reprogramming toward a mixed synthetic-proteolytic state is a central feature of aortic root aneurysm in Marfan syndrome (MFS). Previous work identified Klf4 as a potential mediator of SMC plasticity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44a09ab2ecf7787e173f307b9166755e
https://doi.org/10.1161/atvbaha.122.318509
https://doi.org/10.1161/atvbaha.122.318509
Autor:
Albert J. Pedroza, Alex R. Dalal, Rohan Shad, Nobu Yokoyama, Ken Nakamura, Paul Cheng, Robert C. Wirka, Olivia Mitchel, Michael Baiocchi, William Hiesinger, Thomas Quertermous, Michael P. Fischbein
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42:1154-1168
Background: Aortic root smooth muscle cells (SMC) develop from both the second heart field (SHF) and neural crest. Disparate responses to disease-causing Fbn1 variants by these lineages are proposed to promote focal aortic root aneurysm formation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be331ce48a9c856556936d2b3bf4c8a8
https://doi.org/10.1161/atvbaha.122.317381
https://doi.org/10.1161/atvbaha.122.317381
Publikováno v:
Annals of Biomedical Engineering. 50:1053-1072
Bicuspid aortic valve is the most common congenital heart defect, affecting 1-2% of the global population. Patients with bicuspid valves frequently develop dilation and aneurysms of the ascending aorta. Both hemodynamic and genetic factors are believ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deed8aaf4ee816daddfd6e5c1aad7ca8
https://doi.org/10.1007/s10439-022-02983-4
https://doi.org/10.1007/s10439-022-02983-4
Autor:
Anita Kaw, Albert J. Pedroza, Abhijnan Chattopadhyay, Amelie Pinard, Dongchuan Guo, Kaveeta Kaw, Zhen Zhou, Rohan Shad, Michael P. Fischbein, Callie S. Kwartler, Dianna M. Milewicz
Publikováno v:
Journal of Molecular and Cellular Cardiology. 171:102-104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f552c7454511ace1e1c6af4f36312f5
https://doi.org/10.1016/j.yjmcc.2022.07.004
https://doi.org/10.1016/j.yjmcc.2022.07.004
Publikováno v:
Nature Machine Intelligence. 3:929-935
The National Institutes of Health in 2018 identified key focus areas for the future of artificial intelligence in medical imaging, creating a foundational roadmap for research in image acquisition, algorithms, data standardization and translatable cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d7941a29cb0e5fe28e7dac12337113d
https://doi.org/10.1038/s42256-021-00399-8
https://doi.org/10.1038/s42256-021-00399-8
Autor:
Alexander D. Kaiser, Patpilai Kasinpila, William Hiesinger, Alison L. Marsden, Robyn Fong, Sandra Kong, Rohan Shad, Y. Joseph Woo
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 162:1556-1563
Objective Aortic incompetence (AI) is observed to be accelerated in the continuous-flow left ventricular assist device (LVAD) population and is related to increased mortality. Using computational fluid dynamics (CFD), we investigated the hemodynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2a47152d52a1bb513663a9c8b0e5b6
https://doi.org/10.1016/j.jtcvs.2020.04.164
https://doi.org/10.1016/j.jtcvs.2020.04.164
Autor:
Alex Abramson, Carmel T. Chan, Yasser Khan, Alana Mermin-Bunnell, Naoji Matsuhisa, Robyn Fong, Rohan Shad, William Hiesinger, Parag Mallick, Sanjiv Sam Gambhir, Zhenan Bao
Publikováno v:
Science advances. 8(37)
Assessing the efficacy of cancer therapeutics in mouse models is a critical step in treatment development. However, low-resolution measurement tools and small sample sizes make determining drug efficacy in vivo a difficult and time-intensive task. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843009b4bbc1dd8433b01a4a8ea23faa
https://pubmed.ncbi.nlm.nih.gov/36112679
https://pubmed.ncbi.nlm.nih.gov/36112679
Autor:
Paul Cheng, Albert J Pedroza, Disha Sharma, Chad S Weldy, Trieu Nguyen, Alex R Dalal, Rohan Shad, Juyong B Kim, Michael P Fischbein, Robert Wirka, Thomas Quertermous
Publikováno v:
Circulation Research. 131
Background: Human vascular diseases are the worldwide leading causes of morbidity and mortality. Nearly all human vascular diseases have arterial segment-specific tropisms despite identical exposures to genetic and environmental risk factors. Underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::758f0e63c995210657d5716c8972ed27
https://doi.org/10.1161/res.131.suppl_1.p3006
https://doi.org/10.1161/res.131.suppl_1.p3006