Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Rohan S. Wakade"'
Autor:
Juraj Kramara, Min-Ju Kim, Tomye L. Ollinger, Laura C. Ristow, Rohan S. Wakade, Robert Zarnowski, Melanie Wellington, David R. Andes, Aaron G. Mitchell, Damian J. Krysan
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Protein kinases are critical regulatory proteins in both prokaryotes and eukaryotes. Accordingly, protein kinases represent a common drug target for a wide range of human diseases. Therefore, understanding protein kinase function in human pa
Externí odkaz:
https://doaj.org/article/238395d27ac94527a0cb81bc2924258a
Publikováno v:
mSphere, Vol 9, Iss 4 (2024)
ABSTRACTCandida albicans is a common human fungal pathogen that is also a commensal of the oral cavity and gastrointestinal tract. C. albicans pathogenesis is linked to its transition from budding yeast to filamentous morphologies including hyphae an
Externí odkaz:
https://doaj.org/article/22bfa22056004d11af9558316c97b7dc
Publikováno v:
mSphere, Vol 9, Iss 3 (2024)
ABSTRACTCandida albicans is one of the most common causes of superficial and invasive fungal diseases in humans. Its ability to cause disease is closely linked to its ability to undergo a morphological transition from budding yeast to filamentous for
Externí odkaz:
https://doaj.org/article/113ba96425e04b68a8f002c3fafeea87
Autor:
Virginia E. Glazier, Juraj Kramara, Tomye Ollinger, Norma V. Solis, Robert Zarnowski, Rohan S. Wakade, Min-Ju Kim, Gabriel J. Weigel, Shen-Huan Liang, Richard J. Bennett, Melanie Wellington, David R. Andes, Mark A. Stamnes, Scott G. Filler, Damian J. Krysan
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Candida albicans is a diploid human fungal pathogen that displays significant genomic and phenotypic heterogeneity over a range of virulence traits and in the context of a variety of environmental niches. Here, we show that the effect of Rob
Externí odkaz:
https://doaj.org/article/d9d88ba2cedc4442aa5ec5ea0648059b
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Candida albicans is a commensal of the human gastrointestinal tract and a common cause of human fungal disease, including mucosal infections, such as oropharyngeal candidiasis and disseminated infections of the bloodstream and deep organs. W
Externí odkaz:
https://doaj.org/article/c2cf4858d20e4a1d8965a9f69aa2debe
Autor:
Zhenting Xiang, Rohan S. Wakade, Apoena Aguiar Ribeiro, Weiming Hu, Kyle Bittinger, Aurea Simon-Soro, Dongyeop Kim, Jiyao Li, Damian J. Krysan, Yuan Liu, Hyun Koo
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Candida albicans, a fungus typically found in the mucosal niche, is frequently detected in biofilms formed on teeth (dental plaque) of toddlers with severe childhood caries, a global public health problem that causes rampant tooth decay. How
Externí odkaz:
https://doaj.org/article/27d1d4787f914586a4473eebb8033133
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Candida albicans is one of the most prevalent human fungal pathogens. Its ability to transition between budding yeast and filamentous morphological forms (pseudohyphae and hyphae) is tightly associated with its pathogenesis. Based on in vitr
Externí odkaz:
https://doaj.org/article/f5c85fa415fb4fbd9e7cd7155c73acfe
Autor:
Norma V. Solis, Rohan S. Wakade, Virginia E. Glazier, Tomye L. Ollinger, Melanie Wellington, Aaron P. Mitchell, Scott G. Filler, Damian J. Krysan
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Oropharyngeal candidiasis (OPC) is a common infection that complicates a wide range of medical conditions and can cause either mild or severe disease depending on the patient. The pathobiology of OPC shares many features with candidal biofil
Externí odkaz:
https://doaj.org/article/22dc62d4d45940b79b0284a359807258
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Hyphal tip growth is critical in a range of fungal pathogens, in particular for invasion into animal and plant tissues. In Candida albicans
Externí odkaz:
https://doaj.org/article/e15d3f154fd94939bf04a66a286562b8
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
Candida albicansC. albicans
Externí odkaz:
https://doaj.org/article/ead1f7d5c4034ab2ac0318c1dcce7c69