Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Rohan Maddamsetti"'
Autor:
Rohan Maddamsetti, Yi Yao, Teng Wang, Junheng Gao, Vincent T. Huang, Grayson S. Hamrick, Hye-In Son, Lingchong You
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Horizontal gene transfer (HGT) and gene duplication are often considered as separate mechanisms driving the evolution of new functions. However, the mobile genetic elements (MGEs) implicated in HGT can copy themselves, so positive selection
Externí odkaz:
https://doaj.org/article/d0127204580143ac9c74414d5cf6ce70
Autor:
Rohan Maddamsetti, Nkrumah A Grant
Publikováno v:
PLoS Genetics, Vol 18, Iss 8, p e1010324 (2022)
A general method to infer both positive and purifying selection during the real-time evolution of hypermutator pathogens would be broadly useful. To this end, we introduce a Simple Test to Infer Mode of Selection (STIMS) from metagenomic time series
Externí odkaz:
https://doaj.org/article/5d314a9be18549a38d6b588f6c624016
Autor:
Anna G. Green, Hadeer Elhabashy, Kelly P. Brock, Rohan Maddamsetti, Oliver Kohlbacher, Debora S. Marks
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Our understanding of the residue-level details of protein interactions remains incomplete. Here, the authors show sequence coevolution can be used to infer interacting proteins with residue-level details, including predicting 467 interactions de novo
Externí odkaz:
https://doaj.org/article/1f5d36246a5a4cf98d205592e87dd62a
Autor:
Zachary D Blount, Rohan Maddamsetti, Nkrumah A Grant, Sumaya T Ahmed, Tanush Jagdish, Jessica A Baxter, Brooke A Sommerfeld, Alice Tillman, Jeremy Moore, Joan L Slonczewski, Jeffrey E Barrick, Richard E Lenski
Publikováno v:
eLife, Vol 9 (2020)
Evolutionary innovations allow populations to colonize new ecological niches. We previously reported that aerobic growth on citrate (Cit+) evolved in an Escherichia coli population during adaptation to a minimal glucose medium containing citrate (DM2
Externí odkaz:
https://doaj.org/article/c5355242932347aa9132cbee0e7a1b65
Autor:
Rohan Maddamsetti, Richard E Lenski
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007199 (2018)
Few experimental studies have examined the role that sexual recombination plays in bacterial evolution, including the effects of horizontal gene transfer on genome structure. To address this limitation, we analyzed genomes from an experiment in which
Externí odkaz:
https://doaj.org/article/0af6586ddf614814be99bb54e0b333f9
Autor:
James A Stapleton, Jeongwoon Kim, John P Hamilton, Ming Wu, Luiz C Irber, Rohan Maddamsetti, Bryan Briney, Linsey Newton, Dennis R Burton, C Titus Brown, Christina Chan, C Robin Buell, Timothy A Whitehead
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147229 (2016)
Next-generation DNA sequencing has revolutionized the study of biology. However, the short read lengths of the dominant instruments complicate assembly of complex genomes and haplotype phasing of mixtures of similar sequences. Here we demonstrate a m
Externí odkaz:
https://doaj.org/article/42e75c7b6edc43aba449263d7aa9770a
Publikováno v:
The American Naturalist. 198:93-112
Traits that are unused in a given environment are subject to processes that tend to erode them, leading to reduced fitness in other environments. Although this general tendency is clear, we...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7b7d3eff288b1e24114e5574c897718
https://doi.org/10.1086/714530
https://doi.org/10.1086/714530
Autor:
Hadeer Elhabashy, Debora S. Marks, Oliver Kohlbacher, Rohan Maddamsetti, Anna G. Green, Kelly P Brock
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
Increasing numbers of protein interactions have been identified in high-throughput experiments, but only a small proportion have solved structures. Recently, sequence coevolution-based approaches have led to a breakthrough in predicting monomer prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3262e3e344cec78e3857cd1034e28e
https://doaj.org/article/1f5d36246a5a4cf98d205592e87dd62a
https://doaj.org/article/1f5d36246a5a4cf98d205592e87dd62a
Autor:
Yi Yao, Rohan Maddamsetti, Andrea Weiss, Yuanchi Ha, Teng Wang, Shangying Wang, Lingchong You
Publikováno v:
Nature ecologyevolution. 6(5)
The spread of genes encoding antibiotic resistance is often mediated by horizontal gene transfer (HGT). Many of these genes are associated with transposons, a type of mobile genetic element that can translocate between the chromosome and plasmids. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72604031ff5f843698cade2b09604d42
https://pubmed.ncbi.nlm.nih.gov/35347260
https://pubmed.ncbi.nlm.nih.gov/35347260
Publikováno v:
Nature Microbiology. 4:328-338
Genome analysis should allow the discovery of interdependent loci that together cause antibiotic resistance. In practice, however, the vast number of possible epistatic interactions erodes statistical power. Here, we extend an approach that has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1716cf4394fca5d431d7065665ab796
https://doi.org/10.1038/s41564-018-0309-1
https://doi.org/10.1038/s41564-018-0309-1