Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rohan L. Shah"'
Publikováno v:
Electrophoresis5 References. 42(6)
Host cell proteins (HCPs) are widely regarded as a critical quality attribute for a biotherapeutic product. Bottom up MS is the present gold standard for HCP analysis but suffers from incomplete protein identification due to complex nature of the HCP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082eb2da32279d1abc4a57865b4405f7
https://pubmed.ncbi.nlm.nih.gov/33348443
https://pubmed.ncbi.nlm.nih.gov/33348443
Publikováno v:
Food chemistry. 357
We investigate the hypothesis that proteins and peptides are thermally degraded by hydrolytic bond cleavage of amide bonds, hence yielding shorter peptides as main degradation products. A series of fifteen pentapeptides with varying sequences was sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1851792ce3c557558acb8a5139f448d
https://pubmed.ncbi.nlm.nih.gov/33864995
https://pubmed.ncbi.nlm.nih.gov/33864995
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 117(8)
Recombinant protein production (RPP) in Escherichia coli (E. coli) often induces metabolic burden to the cells that compromise their overall growth and productivity. Amino acid starvation due to RPP is a major contributor of the metabolic burden on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb6ef23a620cb7a3546d852fbebdd8f
https://pubmed.ncbi.nlm.nih.gov/32369182
https://pubmed.ncbi.nlm.nih.gov/32369182
Autor:
Jimena Alvarez Hayes, Juan Marcos Oviedo, Hugo A. Valdez, Rohan L. Shah, Juan Martín Laborde, Marcelo Fernandez Lahore, Miguel Ángel Ayala, María Eugenia Rodríguez, Fabricio Alejandro Maschi
Publikováno v:
Microbiology and Immunology. 61:407-415
Whooping cough, which is caused by Bordetella pertussis and B. parapertussis, is a reemerging disease. New protective antigens are needed to improve the efficacy of current vaccines against both species. Using proteomic tools, it was here found that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::991da2c88170fc4e41a8e49392c1bcb4
https://doi.org/10.1111/1348-0421.12532
https://doi.org/10.1111/1348-0421.12532
Publikováno v:
Journal of chromatography. A. 1620
RPLC-MS/MS is the present workhorse for bottom-up proteomics-based characterization. However it suffers from limited peak capacity and challenges with respect to detection of small and hydrophilic peptides. CZE-MS/MS offers an orthogonal alternative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451bdc399ff4d4e2b9fb2b914014f01e
https://pubmed.ncbi.nlm.nih.gov/32063275
https://pubmed.ncbi.nlm.nih.gov/32063275
Publikováno v:
Food & Function. 7:4082-4091
A liquid chromatography-mass spectrometry-based method for the quantification of intracellular concentrations of dietary phenolics in bacteria was developed. Using this assay, the time-dependent uptake of quercetin and two of its glycosides into gut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad55452c4141a0aaa26c50257bc8f570
https://doi.org/10.1039/c6fo00652c
https://doi.org/10.1039/c6fo00652c