Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Rohan, Kulkarni"'
Publikováno v:
Current Medical Issues, Vol 22, Iss 4, Pp 236-242 (2024)
Over time, there has been a significant increase in the utilization of prone positioning (PP) as a strategy to improve oxygen levels in patients requiring mechanical ventilation for the management of acute respiratory distress syndrome. PP has emerge
Externí odkaz:
https://doaj.org/article/b190e010005146a595165a7bf7514a43
Autor:
Ankita Leekha, Arash Saeedi, K M Samiur Rahman Sefat, Monish Kumar, Melisa Martinez-Paniagua, Adrian Damian, Rohan Kulkarni, Kate Reichel, Ali Rezvan, Shalaleh Masoumi, Xinli Liu, Laurence J. N. Cooper, Manu Sebastian, Courtney M. Sands, Vallabh E. Das, Nimesh B. Patel, Brett Hurst, Navin Varadarajan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Immunization programs against SARS-CoV-2 with commercial intramuscular vaccines prevent disease but are less efficient in preventing infections. Mucosal vaccines can provide improved protection against transmission, ideally for different var
Externí odkaz:
https://doaj.org/article/a940c842f9d44fc59a95b85dd66c762e
Autor:
Ankita Leekha, Arash Saeedi, Monish Kumar, K. M. Samiur Rahman Sefat, Melisa Martinez-Paniagua, Hui Meng, Mohsen Fathi, Rohan Kulkarni, Kate Reichel, Sujit Biswas, Daphne Tsitoura, Xinli Liu, Laurence J. N. Cooper, Courtney M. Sands, Vallabh E. Das, Manu Sebastian, Brett L. Hurst, Navin Varadarajan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Respiratory viral infections cause morbidity and mortality worldwide. Despite the success of vaccines, vaccination efficacy is weakened by the rapid emergence of viral variants with immunoevasive properties. The development of an off-the-she
Externí odkaz:
https://doaj.org/article/9b04c88aae0143498aeb0a85560699b2
Autor:
Melisa J. Montalvo, Irfan N. Bandey, Ali Rezvan, Kwan-Ling Wu, Arash Saeedi, Rohan Kulkarni, Yongshuai Li, Xingyue An, K M Samiur Rahman Sefat, Navin Varadarajan
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-14 (2024)
Abstract Chimeric antigen receptor (CAR) T cell show promise in cancer treatments, but their mechanism of action is not well understood. Decoding the mechanisms used by individual T cells can help improve the efficacy of T cells while also identifyin
Externí odkaz:
https://doaj.org/article/dcd48bed847c4f649497eacb88de0ec8
Autor:
Monish Kumar, Ankita Leekha, Suman Nandy, Rohan Kulkarni, Melisa Martinez-Paniagua, K. M. Samiur Rahman Sefat, Richard C. Willson, Navin Varadarajan
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109817- (2024)
Summary: Although glutamine addiction in cancer cells is extensively reported, there is controversy on the impact of glutamine metabolism on the immune cells within the tumor microenvironment (TME). To address the role of extracellular glutamine, we
Externí odkaz:
https://doaj.org/article/a17f97eb5f124e3abef5f3ee246d9665
Autor:
Rohan Kulkarni, Vijay Maranholkar, Nam Nguyen, Patrick C. Cirino, Richard C. Willson, Navin Varadarajan
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Agonists of the stimulator of interferon genes (STING) pathway are being explored as potential immunotherapeutics for the treatment of cancer and as vaccine adjuvants for infectious diseases. Although chemical synthesis of 2′3’ - cyclic Guanosine
Externí odkaz:
https://doaj.org/article/3ffd210b80c846e1be8aa7892fce9a4c
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100146- (2023)
Externí odkaz:
https://doaj.org/article/ea7a245f68af413195cb138207ed5a52
Autor:
Rohan Kulkarni
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Aging is associated with various hematological disorders and a higher risk of myeloproliferative disorders. An aged hematopoietic system can be characterized by decreased immune function and increased myeloid cell production. Hematopoietic stem cells
Externí odkaz:
https://doaj.org/article/d5b4e61b9b874ab8947dec3837394a8c
Autor:
Elizabeth Andraska, Nolan Skirtich, Dylan McCreary, Rohan Kulkarni, Edith Tzeng, Ryan McEnaney
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Background: During arteriogenesis, outward remodeling of the arterial wall expands luminal diameter to produce increased conductance in developing collaterals. We have previously shown that diameter expansion without loss of internal elastic lamina (
Externí odkaz:
https://doaj.org/article/4055c77029944b2889a87c528e7b7aa9
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Lower extremity arterial occlusive disease (AOD) results in significant morbidity and mortality for the population, with up to 10% of patients ultimately requiring amputation. An alternative method for non-surgical revascularization which is yet to b
Externí odkaz:
https://doaj.org/article/af19d21481fd4eacb260525523636a13