Výsledky vyhledávání - "Rognum Torleiv O"

Akademický článek

Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas

Autor: Lind Guro E, Danielsen Stine A, Ahlquist Terje, Merok Marianne A, Andresen Kim, Skotheim Rolf I, Hektoen Merete, Rognum Torleiv O, Meling Gunn I, Hoff Geir, Bretthauer Michael, Thiis-Evensen Espen, Nesbakken Arild, Lothe Ragnhild A

Publikováno v: Molecular Cancer, Vol 10, Iss 1, p 85 (2011)

Abstract Background The presence of cancer-specific DNA methylation patterns in epithelial colorectal cells in human feces provides the prospect of a simple, non-invasive screening test for colorectal cancer and its precursor, the adenoma. This study

Externí odkaz: https://doaj.org/article/074c02ec5a9444f883efce1c6a2f9981

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Akademický článek

Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers

Autor: Vatn Morten, Meling Gunn I, Costa Vera L, Lind Guro E, Ahlquist Terje, Hoff Geir S, Rognum Torleiv O, Skotheim Rolf I, Thiis-Evensen Espen, Lothe Ragnhild A

Publikováno v: Molecular Cancer, Vol 7, Iss 1, p 94 (2008)

Abstract Background Multiple epigenetic and genetic changes have been reported in colorectal tumors, but few of these have clinical impact. This study aims to pinpoint epigenetic markers that can discriminate between non-malignant and malignant tissu

Externí odkaz: https://doaj.org/article/d9b658b17e4049648fdb6834131fe976

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Akademický článek

Hypermethylated MAL gene – a silent marker of early colon tumorigenesis

Autor: Kallioniemi Anne, Alonso Miguel A, Eknæs Mette, Berg Marianne, Kolberg Matthias, Ahlquist Terje, Lind Guro E, Meling Gunn I, Skotheim Rolf I, Rognum Torleiv O, Thiis-Evensen Espen, Lothe Ragnhild A

Publikováno v: Journal of Translational Medicine, Vol 6, Iss 1, p 13 (2008)

Abstract Background Tumor-derived aberrantly methylated DNA might serve as diagnostic biomarkers for cancer, but so far, few such markers have been identified. The aim of the present study was to investigate the potential of the MAL (T-cell different

Externí odkaz: https://doaj.org/article/fe8f6a4f44d24e4dada3ede8e6d8589f

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Akademický článek

Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses

Autor: Myklebost Ola, Nesland Jahn M, Brandal Lin T, Meling Gunn I, Diep Chieu B, Lind Guro E, Kleivi Kristine, Rognum Torleiv O, Giercksky Karl-Erik, Skotheim Rolf I, Lothe Ragnhild A

Publikováno v: Molecular Cancer, Vol 6, Iss 1, p 2 (2007)

Abstract Background Despite the fact that metastases are the leading cause of colorectal cancer deaths, little is known about the underlying molecular changes in these advanced disease stages. Few have studied the overall gene expression levels in me

Externí odkaz: https://doaj.org/article/063f9c713988469398bda4c688fa0381

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Akademický článek

A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines

Autor: Rognum Torleiv O, Hamelin Richard, Meling Gunn I, Løvig Tone, Thorstensen Lin, Lind Guro E, Esteller Manel, Lothe Ragnhild A

Publikováno v: Molecular Cancer, Vol 3, Iss 1, p 28 (2004)

Abstract Background Tumor cell lines are commonly used as experimental tools in cancer research, but their relevance for the in vivo situation is debated. In a series of 11 microsatellite stable (MSS) and 9 microsatellite unstable (MSI) colon cancer

Externí odkaz: https://doaj.org/article/0da0d89275fa4203a664387a3692751b

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