Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rogier M. Schoeman"'
Autor:
Rogier M. Schoeman, Wesley T. E. van den Beld, Evelien W. M. Kemna, Floor Wolbers, Jan C. T. Eijkel, Albert van den Berg
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract We present a microfluidic chip that enables electrofusion of cells in microdroplets, with exchange of nuclear components. It is shown, to our knowledge for the first time, electrofusion of two HL60 cells, inside a microdroplet. This is the c
Externí odkaz:
https://doaj.org/article/3606b79671de4d729848e07db56bd288
Publikováno v:
Platelets, Vol 28, Iss 5, Pp 463-471 (2017)
Platelet adhesion and aggregation, coagulation, fibrin formation, and fibrinolysis are regulated by the forces and flows imposed by blood at the site of a vascular injury. Flow chambers designed to observe these events are an indispensable part of do
Externí odkaz:
https://doaj.org/article/6d28f4eac8e14b668afb64cb9c550e47
Publikováno v:
Current Opinion in Biotechnology
Generating novel functionality from well characterised synthetic parts and modules lies at the heart of synthetic biology. Ideally, circuitry is rationally designed in silico with quantitatively predictive models to predetermined design specification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8f22d82c85dd78153e40554ddfad78
Autor:
Aaron L. Fogelson, Karin Leiderman, Keith B. Neeves, Marcus Lehmann, Nicholas A. Danes, Kuldeepsinh Rana, Rogier M. Schoeman, J. Di Paola
Publikováno v:
Cellular and Molecular Bioengineering. 10:3-15
Hemostasis is the process of sealing a vascular injury with a thrombus to arrest bleeding. The type of thrombus that forms depends on the nature of the injury and hemodynamics. There are many models of intravascular thrombus formation whereby blood i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ac1b120b7ba809c33a366e9750e770
https://doi.org/10.1007/s12195-016-0469-0
https://doi.org/10.1007/s12195-016-0469-0
Autor:
Jan C.T. Eijkel, Evelien W. M. Kemna, Floor Wolbers, Rogier M. Schoeman, Albert van den Berg, Wesley T. E. van den Beld
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific reports, 8:3714. Nature Publishing Group
Scientific Reports
Scientific reports, 8:3714. Nature Publishing Group
Scientific Reports
We present a microfluidic chip that enables electrofusion of cells in microdroplets, with exchange of nuclear components. It is shown, to our knowledge for the first time, electrofusion of two HL60 cells, inside a microdroplet. This is the crucial in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695d2366324c39ce4c6270de219f0bfc
https://doi.org/10.1038/s41598-018-21993-8
https://doi.org/10.1038/s41598-018-21993-8
Platelet adhesion and aggregation, coagulation, fibrin formation, and fibrinolysis are regulated by the forces and flows imposed by blood at the site of a vascular injury. Flow chambers designed to observe these events are an indispensable part of do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5609912797f94a647ce085c9c7f8631
https://europepmc.org/articles/PMC6131111/
https://europepmc.org/articles/PMC6131111/
Autor:
Joseph R. Samaniuk, Alison M. Wallbank, Keith B. Neeves, Patrick J. Krohl, Martine Jandrot-Perrus, Marcus Lehmann, Rogier M. Schoeman
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 38(5)
Objective— The objective of this study was to measure the role of platelets and red blood cells on thrombus propagation in an in vitro model of venous valvular stasis. Approach and Results— A microfluidic model with dimensional similarity to huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51aaa2118f7dfd1fa991c1a30eb7c6df
https://pubmed.ncbi.nlm.nih.gov/29695530
https://pubmed.ncbi.nlm.nih.gov/29695530
Autor:
Rogier M. Schoeman, Tonguc O. Tasci, Keith B. Neeves, Dante Disharoon, Paco S. Herson, David W. M. Marr, Kuldeepsinh Rana
Publikováno v:
Small
Thrombi that occlude blood vessels can be resolved with fibrinolytic agents that degrade fibrin, the polymer that forms between and around platelets to provide mechanical stability. Fibrinolysis rates however are often constrained by transport-limite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b09893b18d3aa59ef0b225d0177009c
https://pubmed.ncbi.nlm.nih.gov/28719063
https://pubmed.ncbi.nlm.nih.gov/28719063
Publikováno v:
ELECTROPHORESIS. 35:385-392
In this article, we present a microfluidic device capable of successive high-yield single-cell encapsulation in droplets, with additional droplet pairing, fusion, and shrinkage. Deterministic single-cell encapsulation is realized using Dean-coupled i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56ccee24e28762fc52ef228801d96f3e
https://doi.org/10.1002/elps.201300179
https://doi.org/10.1002/elps.201300179
Autor:
Albert van den Berg, David A. Weitz, Floor Wolbers, Rogier M. Schoeman, Evelien W. M. Kemna, I. Vermes
Publikováno v:
Lab on a chip, 12(16), 2881-2887. Royal Society of Chemistry
Lab on a Chip
Lab on a Chip
In this article high-yield (77%) and high-speed (2700 cells s(-1)) single cell droplet encapsulation is described using a Dean-coupled inertial ordering of cells in a simple curved continuous microchannel. By introducing the Dean force, the particles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b27f5363968ee5eb0bcd434a315ca6c
https://doi.org/10.1039/c2lc00013j
https://doi.org/10.1039/c2lc00013j