Zobrazeno 1 - 10 of 208 pro vyhledávání: '"Rogier M. Bertina"'
1
Akademický článek
Negatively charged phospholipids stimulate factor XI activation by thrombin
Autor: Farida Omarova, Jan Rosing, Rogier M. Bertina, Elisabetta Castoldi
Publikováno v: Thrombosis Update, Vol 2, Iss , Pp 100022- (2021)
Introduction: Coagulation factor XI (FXI) is the zymogen of the serine-protease FXIa, which contributes to thrombin formation by activating factor IX. FXI can be activated by factor XIIa or thrombin, but thrombin-catalysed FXI activation is highly in
Externí odkaz: https://doaj.org/article/9c69fef96eb94260a573457cc8e63b97
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2
Akademický článek
Endothelial protein C receptor polymorphisms and risk of myocardial infarction
Autor: Pilar Medina, Silvia Navarro, Javier Corral, Esther Zorio, Vanessa Roldán, Amparo Estellés, Amparo Santamaría, Francisco Marín, Joaquín Rueda, Rogier M. Bertina, Francisco España, for the RECAVA Thrombosis Groups
Publikováno v: Haematologica, Vol 93, Iss 9 (2008)
Background Haplotypes A1 and A3 in the endothelial protein C receptor gene are tagged by the 4678G/C and 4600A/G polymorphisms, respectively, and have been reported to influence the risk of venous thromboembolism. We assessed whether these haplotypes
Externí odkaz: https://doaj.org/article/d36830565f2f47e0afe7228579ea76ab
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4
Akademický článek
Haplotypes of the EPCR gene, prothrombin levels, and the risk of venous thrombosis in carriers of the prothrombin G20210A mutation
Autor: Silvia Navarro, Pilar Medina, Yolanda Mira, Amparo Estellés, Piedad Villa, Fernando Ferrando, Amparo Vayá, Rogier M. Bertina, Francisco España
Publikováno v: Haematologica, Vol 93, Iss 6 (2008)
Background Haplotypes A1 and A3 in the endothelial protein C receptor (EPCR) gene are tagged by 4678G/C and 4600A/G respectively. We assessed whether these haplotypes modify the risk of venous thromboembolism in carriers of the prothrombin 20210A all
Externí odkaz: https://doaj.org/article/f6338203ec7d42e5989dd03161821ae7
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5
Akademický článek
A novel serine protease secreted by medicinal maggots enhances plasminogen activator-induced fibrinolysis.
Autor: Mariena J A van der Plas, Anders S Andersen, Sheresma Nazir, Nico H van Tilburg, Peter R Oestergaard, Karen A Krogfelt, Jaap T van Dissel, Paul J Hensbergen, Rogier M Bertina, Peter H Nibbering
Publikováno v: PLoS ONE, Vol 9, Iss 3, p e92096 (2014)
Maggots of the blowfly Lucilia sericata are used for the treatment of chronic wounds. As haemostatic processes play an important role in wound healing, this study focused on the effects of maggot secretions on coagulation and fibrinolysis. The result
Externí odkaz: https://doaj.org/article/be8022d8983d463a92284b4352156393
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6
Akademický článek
Maternal TLR4 and NOD2 gene variants, pro-inflammatory phenotype and susceptibility to early-onset preeclampsia and HELLP syndrome.
Autor: Bas B van Rijn, Arie Franx, Eric A P Steegers, Christianne J M de Groot, Rogier M Bertina, Gerard Pasterkamp, Hieronymus A M Voorbij, Hein W Bruinse, Mark Roest
Publikováno v: PLoS ONE, Vol 3, Iss 4, p e1865 (2008)
BACKGROUND: Altered maternal inflammatory responses play a role in the development of preeclampsia and the hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome. We examined whether allelic variants of the innate immune receptors Toll-
Externí odkaz: https://doaj.org/article/580998e65c6b4dba95c0f05d4445cbd1
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7
Tissue factor-bearing microparticles and CA19.9: two players in pancreatic cancer-associated thrombosis?
Autor: Fred P.H.T.M. Romijn, Margot E T Tesselaar, Rogier M. Bertina, Susanne Osanto, F J Sherida H Woei-A-Jin, Patrica Garcia Rodriguez
Publikováno v: British Journal of Cancer
British Journal of Cancer, 115(3), 332-338. NATURE PUBLISHING GROUP
British Journal of Cancer, 115(3), 332-338
BACKGROUND: Cancer-related venous thromboembolism (VTE) heralds a poor prognosis, especially in pancreatic adenocarcinoma (PAC). Tissue factor (TF) is implicated as one of the main culprits in PAC-associated VTE and disease progression. METHODS: In a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56a72fa2e9d09dbbbb15b03e62b6f45
https://doi.org/10.1038/bjc.2016.170
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8
Fibrinogen γ′ increases the sensitivity to activated protein C in normal and factor V Leiden plasma
Autor: Elisabetta Castoldi, Paolo Simioni, Rogier M. Bertina, Jan Rosing, Shirley Uitte de Willige, Farida Omarova, Robert A. S. Ariëns
Publikováno v: Blood, 124(9), 1531-1538. The American Society of Hematology
Activated protein C (APC) resistance, often associated with the factor V (FV) Leiden mutation, is the most common risk factor for venous thrombosis. We observed increased APC resistance in carriers of fibrinogen gamma gene (FGG) haplotype 2, which is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd46d52d02a49add69aab84b5ace465
https://doi.org/10.1182/blood-2014-02-554055
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9
Genome-wide linkage scan in affected sibling pairs identifies novel susceptibility region for venous thromboembolism: Genetics In Familial Thrombosis study
Autor: V. Van Marion, R. van Minkelen, F. R. Rosendaal, M. den Heijer, Jeanine J. Houwing-Duistermaat, M. de Visser, Hans L. Vos, Rogier M. Bertina, Jeroen Eikenboom, P.E. Slagboom
Publikováno v: Journal of Thrombosis and Haemostasis, 11(8), 1474-1484. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 11(8), 1474-1484
de Visser, M C H, van Minkelen, R, van Marion, V, den Heijer, M, Eikenboom, J, de Vos, H, Slagboom, P, Houwing-Duistermaat, J, Rosendaal, F & Bertina, R 2013, ' Genome-wide linkage scan in affected sibling pairs identifies novel susceptibility region for venous thromboembolism: Genetics In Familial Thrombosis study ', Journal of Thrombosis and Haemostasis, vol. 11, no. 8, pp. 1474-1484 . https://doi.org/10.1111/jth.12313
Summary. Background: Venous thromboembolism (VTE) is a multicausal disorder involving environmental and genetic risk factors. In many thrombophilic families the clustering of thrombotic events cannot be explained by known genetic risk factors, indica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27d44907fc1f08ea38b9437f1eb1591
https://doi.org/10.1111/jth.12313
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10
Microparticle‐associated tissue factor activity, venous thromboembolism and mortality in pancreatic, gastric, colorectal and brain cancer patients
Autor: Alexandra Kaider, Johannes Thaler, Nigel Mackman, Rogier M. Bertina, Christoph C. Zielinski, Christine Marosi, Nigel S. Key, Werner Scheithauer, Cihan Ay, D. A. Barcel, Gabriela Kornek, Ingrid Pabinger
Publikováno v: Journal of Thrombosis and Haemostasis. 10:1363-1370
Summary. Background: Tissue factor (TF) expression by tumors contributes to tumor growth. Release of TF-positive microparticles (MPs) may contribute to venous thromboembolism (VTE). Objectives: To conduct a prospective cohort study to determine wheth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae05d042f23d149b834c42fc6550247e
https://doi.org/10.1111/j.1538-7836.2012.04754.x
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