Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rogier B. Poorthuis"'
Autor:
Jan Hartung, Anna Schroeder, Rodrigo Alejandro Péréz Vázquez, Rogier B. Poorthuis, Johannes J. Letzkus
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114212- (2024)
Summary: Diverse types of inhibitory interneurons (INs) impart computational power and flexibility to neocortical circuits. Whereas markers for different IN types in cortical layers 2–6 (L2–L6) have been instrumental for generating a wealth of fu
Externí odkaz:
https://doaj.org/article/bdd4d31fc4e145d296a0f3db068074a8
Autor:
Rogier B. Poorthuis, Karzan Muhammad, Mantian Wang, Matthijs B. Verhoog, Stephan Junek, Anne Wrana, Huibert D. Mansvelder, Johannes J. Letzkus
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 951-958 (2018)
Summary: Inhibitory interneurons govern virtually all computations in neocortical circuits and are in turn controlled by neuromodulation. While a detailed understanding of the distinct marker expression, physiology, and neuromodulator responses of di
Externí odkaz:
https://doaj.org/article/990ba16641ac48559a7e8c9f3d74b7d3
Autor:
Victor Briz, Leonardo Restivo, Emanuela Pasciuto, Konrad Juczewski, Valentina Mercaldo, Adrian C. Lo, Pieter Baatsen, Natalia V. Gounko, Antonella Borreca, Tiziana Girardi, Rossella Luca, Julie Nys, Rogier B. Poorthuis, Huibert D. Mansvelder, Gilberto Fisone, Martine Ammassari-Teule, Lutgarde Arckens, Patrik Krieger, Rhiannon Meredith, Claudia Bagni
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Brain cytoplasmic (BC1) RNA is a non-coding RNA that has been implicated in translational regulation, seizure, and anxiety. Here, the authors show that in the cortex, BC1 RNA is required for sensory deprivation-induced structural plasticity of dendri
Externí odkaz:
https://doaj.org/article/c904b79eda0c41d194c02e95b2cd0dea
Autor:
Jelmer Willems, Arthur P H de Jong, Nicky Scheefhals, Eline Mertens, Lisa A E Catsburg, Rogier B Poorthuis, Fred de Winter, Joost Verhaagen, Frank J Meye, Harold D MacGillavry
Publikováno v:
PLoS Biology, Vol 18, Iss 4, p e3000665 (2020)
The correct subcellular distribution of proteins establishes the complex morphology and function of neurons. Fluorescence microscopy techniques are invaluable to investigate subcellular protein distribution, but they suffer from the limited ability t
Externí odkaz:
https://doaj.org/article/3f6aae25fa144ec6809509e7803446db
Autor:
Johannes J. Letzkus, Karzan Muhammad, Mantian Wang, Matthijs B. Verhoog, Anne Wrana, Huibert D. Mansvelder, Stephan Junek, Rogier B. Poorthuis
Publikováno v:
Poorthuis, R B, Muhammad, K, Wang, M, Verhoog, M B, Junek, S, Wrana, A, Mansvelder, H D & Letzkus, J J 2018, ' Rapid Neuromodulation of Layer 1 Interneurons in Human Neocortex ', Cell Reports, vol. 23, no. 4, pp. 951-958 . https://doi.org/10.1016/j.celrep.2018.03.111
Cell Reports
Cell Reports, 23(4), 951-958. Cell Press
Cell Reports, Vol 23, Iss 4, Pp 951-958 (2018)
Cell Reports
Cell Reports, 23(4), 951-958. Cell Press
Cell Reports, Vol 23, Iss 4, Pp 951-958 (2018)
Summary Inhibitory interneurons govern virtually all computations in neocortical circuits and are in turn controlled by neuromodulation. While a detailed understanding of the distinct marker expression, physiology, and neuromodulator responses of dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938980582fd69575745152dd12be3c1b
https://doi.org/10.1016/j.celrep.2018.03.111
https://doi.org/10.1016/j.celrep.2018.03.111
Autor:
Johannes J. Letzkus, Tamas Dalmay, Julijana Gjorgjieva, Philip Tovote, Jan Hartung, Jérémy Signoret-Genest, Sebastian Onasch, De-Lin Pu, Yave R. Lozano, Elisabeth Abs, Rogier B. Poorthuis
Publikováno v:
Neuron
Summary Memory of cues associated with threat is critical for survival and a leading model for elucidating how sensory information is linked to adaptive behavior by learning. Although the brain-wide circuits mediating auditory threat memory have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc157102488aa403e1ef1cf6333f3e02
https://pubmed.ncbi.nlm.nih.gov/31727549
https://pubmed.ncbi.nlm.nih.gov/31727549
Autor:
Karl-Klaus Conzelmann, Dahlia Kushinsky, Rogier B. Poorthuis, De Lin Pu, Daniella Apelblat, M. Belén Pardi, Karzan Muhammad, Elisabeth Abs, Leona Enke, Johannes J. Letzkus, Max Ferdinand Eizinger, Ivo Spiegel
Publikováno v:
Neuron
Summary A wealth of data has elucidated the mechanisms by which sensory inputs are encoded in the neocortex, but how these processes are regulated by the behavioral relevance of sensory information is less understood. Here, we focus on neocortical la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859df98889c6a976e2fcfda66d516747
https://hdl.handle.net/21.11116/0000-0008-F9A8-2
https://hdl.handle.net/21.11116/0000-0008-F9A8-2
Publikováno v:
Poorthuis, R B, Bloem, B, Verhoog, M B & Mansvelder, H D 2013, ' Layer-specific interference with cholinergic signaling in the prefrontal cortex by smoking concentrations of nicotine ', The Journal of Neuroscience, vol. 33, no. 11, pp. 4843-4853 . https://doi.org/10.1523/JNEUROSCI.5012-12.2013
The Journal of Neuroscience, 33(11), 4843-4853. Society for Neuroscience
Journal of Neuroscience
Journal of Neuroscience; Vol 33
The Journal of Neuroscience, 33(11), 4843-4853. Society for Neuroscience
Journal of Neuroscience
Journal of Neuroscience; Vol 33
Adolescence is a period in which the developing prefrontal cortex (PFC) is sensitive to maladaptive changes when exposed to nicotine. Nicotine affects PFC function and repeated exposure to nicotine during adolescence impairs attention performance and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1982899a05244403792ebdc10ff2c361
https://research.vu.nl/en/publications/57530ca0-9776-4acf-ba1d-4b3e9bcf6211
https://research.vu.nl/en/publications/57530ca0-9776-4acf-ba1d-4b3e9bcf6211
Autor:
Sabine Spijker, Huibert D. Mansvelder, Bernard Bloem, Maarten Loos, Karine Guillem, Uwe Maskos, August B. Smit, Rogier B. Poorthuis
Publikováno v:
Science; Vol 333
Science
Science, 2011, 333 (6044), pp.888-891. ⟨10.1126/science.1207079⟩
Science, 333, 888-891. American Association for the Advancement of Science
Guillem, K, Bloem, B, Poorthuis, R B, Loos, M, Smit, A B, Maskos, U, Spijker, S & Mansvelder, H D 2011, ' Nicotinic acetylcholine receptor β2-subunits in the medial prefrontal cortex control attention ', Science, vol. 333, pp. 888-891 . https://doi.org/10.1126/science.1207079
Science, American Association for the Advancement of Science, 2011, 333 (6044), pp.888-891. ⟨10.1126/science.1207079⟩
Science
Science, 2011, 333 (6044), pp.888-891. ⟨10.1126/science.1207079⟩
Science, 333, 888-891. American Association for the Advancement of Science
Guillem, K, Bloem, B, Poorthuis, R B, Loos, M, Smit, A B, Maskos, U, Spijker, S & Mansvelder, H D 2011, ' Nicotinic acetylcholine receptor β2-subunits in the medial prefrontal cortex control attention ', Science, vol. 333, pp. 888-891 . https://doi.org/10.1126/science.1207079
Science, American Association for the Advancement of Science, 2011, 333 (6044), pp.888-891. ⟨10.1126/science.1207079⟩
International audience; More than one-third of all people are estimated to experience mild to severe cognitive impairment as they age. Acetylcholine (ACh) levels in the brain diminish with aging, and nicotinic ACh receptor (nAChR) stimulation is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc2553c901b58fff3d2faf93aaf85f6
Publikováno v:
Poorthuis, R B, Goriounova, N A, Couey, J J & Mansvelder, H D 2009, ' Nicotinic actions on neuronal networks for cognition: general principles and long-term consequences ', Biochemical Pharmacology, vol. 78, no. 7, pp. 668-676 . https://doi.org/10.1016/j.bcp.2009.04.031
Biochemical Pharmacology, 78(7), 668-676. Elsevier Inc.
Biochemical Pharmacology, 78(7), 668-676. Elsevier Inc.
Nicotine enhances cognitive performance in humans and laboratory animals. The immediate positive actions of nicotine on learning, memory and attention are well-documented. Several brain areas involved in cognition, such as the prefrontal cortex, have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff8a44b5466829d4286312ffcae5f3c
https://hdl.handle.net/1871/29587
https://hdl.handle.net/1871/29587