Humoral and cellular immune responses after COVID-19 vaccination of lung transplant recipients and patients on the waiting list: a 6-month follow-up

Autor: Rogier A. S. Hoek, Siqi Liu, Corine H. GeurtsvanKessel, Erik A. M. Verschuuren, Judith M. Vonk, Merel E. Hellemons, Mirjam Kool, Nynke Wijbenga, Susanne Bogers, Sandra Scherbeijn, Sharona Rugebregt, Johanna P. van Gemert, Willie N. Steenhuis, Hubert G. M. Niesters, Debbie van Baarle, Rory D. de Vries, Coretta Van Leer Buter

Publikováno v: Frontiers in Immunology, Vol 14 (2024)

BackgroundData on cellular response and the decay of antibodies and T cells in time are scarce in lung transplant recipients (LTRs). Additionally, the development and durability of humoral and cellular immune responses have not been investigated in p

Externí odkaz: https://doaj.org/article/28c282fddf214873b95b8fd9dcd05809

Organizing Pneumonia and Microvascular Fibrosis as Late Sequelae after a COVID-19 Infection. A Case Report

Autor: Johan L. Dikken, Alexander P. W. M. Maat, Janina L. Wolf, Henrik Endeman, Rogier A. S. Hoek, Ad J. J. C. Bogers, Edris A. F. Mahtab

Publikováno v: Surgeries, Vol 2, Iss 2, Pp 190-198 (2021)

We report a patient with COVID-19 requiring hospitalization for two weeks, complicated by multiple segmental pulmonary embolisms for which dabigatran was initiated. After clearing the infection, the patient remained asymptomatic for 5 months. He was

Externí odkaz: https://doaj.org/article/d779da9a558f4bcfa24fb2e5caef2f7e

Enhanced Bruton’s tyrosine kinase in B-cells and autoreactive IgA in patients with idiopathic pulmonary fibrosis

Autor: Peter Heukels, Jennifer A. C. van Hulst, Menno van Nimwegen, Carian E. Boorsma, Barbro N. Melgert, Jan H. von der Thusen, Bernt van den Blink, Rogier A. S. Hoek, Jelle R. Miedema, Stefan F. H. Neys, Odilia B. J. Corneth, Rudi W. Hendriks, Marlies S. Wijsenbeek, Mirjam Kool

Publikováno v: Respiratory Research, Vol 20, Iss 1, Pp 1-13 (2019)

Abstract Rationale Idiopathic Pulmonary Fibrosis (IPF) is thought to be triggered by repeated alveolar epithelial cell injury. Current evidence suggests that aberrant immune activation may contribute. However, the role of B-cell activation remains un

Externí odkaz: https://doaj.org/article/13715e292aad4ffcbe1f2d8589b1faa4

Clinical Characteristics and Outcomes of Immunocompromised Patients With Coronavirus Disease 2019 Caused by the Omicron Variant: A Prospective, Observational Study

Autor: S Reshwan K Malahe, Rogier A S Hoek, Virgil A S H Dalm, Annoek E C Broers, Caroline M den Hoed, Olivier C Manintveld, Carla C Baan, Charlotte M van Deuzen, Grigorios Papageorgiou, Hannelore I Bax, Jeroen J Van Kampen, Merel E Hellemons, Marcia M L Kho, Rory D de Vries, Richard Molenkamp, Marlies E J Reinders, Bart J A Rijnders

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 76(3):ciac571, e172-e178. Oxford University Press

Background Illness after infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant is less severe compared with previous variants. Data on the disease burden in immunocompromised patients are lacking. We investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a8fe6812bf0059b6387a5ffdfac947
https://doi.org/10.1093/cid/ciac571

Lung Transplantation in Gaucher Disease: A Learning Lesson in Trying to Avoid Both Scylla and Charybdis

Autor: Geertje M, de Boer, Laura, van Dussen, Leon M, van den Toorn, Michael A, den Bakker, Rogier A S, Hoek, Dennis A, Hesselink, Carla E M, Hollak, Peter Th W, van Hal

Publikováno v: Chest. 149(1)

Gaucher disease (GD), a lysosomal storage disorder, may result in end-stage lung disease. We report successful bilateral lung transplantation in a 49-year-old woman with GD complicated by severe pulmonary hypertension and fibrotic changes in the lung

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5451218ff5768834ee49de0d65cec7d3
https://pubmed.ncbi.nlm.nih.gov/26757299