Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Roghaye Gharae"'
Valproic acid, a histone deacetylase inhibitor, enhances radiosensitivity in breast cancer cell line
Autor:
Ahmad Yarmohamadi, Jahanbakhsh Asadi, Roghaye Gharaei, Mostafa Mir, Alireza Khoshbin Khoshnazar
Publikováno v:
Journal of Radiation and Cancer Research, Vol 9, Iss 2, Pp 86-92 (2018)
Purpose: Valproic acid (VPA) is used mainly for the treatment of epilepsy and other seizure disorders, however, it is known to be one of histone deacetylase (HDAC) inhibitors. HDACIs have represented roles in radiation-sensitizing of cancer cells. Th
Externí odkaz:
https://doaj.org/article/4b329b7706dc4c6cae985236e7f68ae3
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 15, Iss 2, Pp 419-422 (2017)
Non-synonymous single nucleotide polymorphisms (nsSNPs) are a type of genetic mutations that result in amino acid substitution of the encoded proteins that may potentially affect its function and phenotype. An In Silico assay has been carried out by
Externí odkaz:
https://doaj.org/article/fa9f3d24bd3e4b868c1762bca4ce53e7
Autor:
Esmaeil Samadian, Ayyoob Khosravi, Roghaye Gharae, Mostafa Mir, Seyed Ahmad Sajjadi, Fahimeh Mohammad Abadi, Nader Hashemi, Sahar Alijanpour, Hamid Reza Joshaghani
Publikováno v:
Medical Laboratory Journal, Vol 10, Iss 3, Pp 1-5 (2016)
ABSTRACT Background and Objective: Genetic variations in the gene encoding endothelial nitric oxide synthase (eNOS) enzyme affect the susceptibility to cardiovascular disease. Identification of the way these changes affect eNOS structure and functi
Externí odkaz:
https://doaj.org/article/b2d71f4651d546e5bc03ed3afb9dc2ff
Autor:
Roghaye Gharae, Ayyoob Khosravi, Hamidreza Joshaghani, Mostafa Mir, Seyed Ahmad Sajjadi, Esmaeil Samadian, Fahimeh Mohammad Abadi, Sahar Alijanpour, Nader Hashemi
Publikováno v:
Medical Laboratory Journal, Vol 10, Iss 3, Pp 1-5 (2016)
Background and Objective: Genetic variations in the gene encoding endothelial nitric oxide synthase (eNOS) enzyme affect the susceptibility to cardiovascular disease. Identification of the way these changes affect eNOS structure and function in labor
Publikováno v:
International Journal of Reproductive BioMedicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is the leading cause of the new deadly pneumonia named coronavirus disease 2019 (COVID-19) pandemic. This pathogen has different co-receptors on various tissues, resulting in va
Externí odkaz:
https://doaj.org/article/6d7719d3eccd470488e98e2b57976638
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 18, Iss 7, Pp 700-704 (2015)
Objective(s):Valproic acid (VPA), a drug used in the treatment of neurological disorders, has been shown to have cytotoxic effects on cancer cells through different mechanisms. Telomerase, a ribonucleoprotein reverse transcriptase, is responsible for
Externí odkaz:
https://doaj.org/article/479f3a961be845c0b4be9cb326f17e0d