Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rogers M. Brown"'
Autor:
Martin L Basch, Rogers M Brown II, Hsin-I Jen, Fatih Semerci, Frederic Depreux, Renée K Edlund, Hongyuan Zhang, Christine R Norton, Thomas Gridley, Susan E Cole, Angelika Doetzlhofer, Mirjana Maletic-Savatic, Neil Segil, Andrew K Groves
Publikováno v:
eLife, Vol 5 (2016)
The signals that induce the organ of Corti and define its boundaries in the cochlea are poorly understood. We show that two Notch modifiers, Lfng and Mfng, are transiently expressed precisely at the neural boundary of the organ of Corti. Cre-Lox fate
Externí odkaz:
https://doaj.org/article/ef349eec4d0042e7ac246fa6ab85e782
Publikováno v:
Dev Biol
The five vestibular organs of the inner ear derive from patches of prosensory cells that express the transcription factor SOX2 and the Notch ligand JAG1. Previous work suggests that JAG1-mediated Notch signaling is both necessary and sufficient for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c848edac613a2c8dc473a179aa973d
https://pubmed.ncbi.nlm.nih.gov/32147304
https://pubmed.ncbi.nlm.nih.gov/32147304
Autor:
Rende Gu, Tegy J. Vadakkan, Andrew K. Groves, Tiantian Cai, Mary E. Dickinson, Alyssa L. Crowder, Victor G. Piazza, Rogers M. Brown, Chih-Wei Hsu
Publikováno v:
Developmental Biology. 414:72-84
The transcription factor Sox2 is both necessary and sufficient for the generation of sensory regions of the inner ear. It regulates expression of the Notch ligand Jag1 in prosensory progenitors, which signal to neighboring cells to up-regulate Sox2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b6fcd461c4b71b9c42bf5a3df50280
https://doi.org/10.1016/j.ydbio.2016.03.027
https://doi.org/10.1016/j.ydbio.2016.03.027
Autor:
Rogers M. Brown, Andrew K. Groves
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 370 (2020)
Biomolecules
Biomolecules
The vertebrate inner ear is responsible for detecting sound, gravity, and head motion. These mechanical forces are detected by mechanosensitive hair cells, arranged in a series of sensory patches in the vestibular and cochlear regions of the ear. Hai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbf5ff46053284ca23b4d813341752c
https://doi.org/10.3390/biom10030370
https://doi.org/10.3390/biom10030370
Autor:
Fatih Semerci, Hsin-I Jen, Christine R. Norton, Hongyuan Zhang, Rogers M. Brown, Mirjana Maletic-Savatic, Thomas Gridley, Neil Segil, Renée K. Edlund, Martin L. Basch, Angelika Doetzlhofer, Susan E. Cole, Frederic Depreux, Andrew K. Groves
Publikováno v:
eLife, Vol 5 (2016)
eLife
eLife
The signals that induce the organ of Corti and define its boundaries in the cochlea are poorly understood. We show that two Notch modifiers, Lfng and Mfng, are transiently expressed precisely at the neural boundary of the organ of Corti. Cre-Lox fate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91c8ae758cce5e3390d2231bdda91bf
https://doi.org/10.7554/elife.19921
https://doi.org/10.7554/elife.19921
Autor:
Hongyuan Zhang, Neil Segil, Renée K. Edlund, Fatih Semerci, Hsin-I Jen, Christine R. Norton, Frederic Depreux, Angelika Doetzlhofer, Rogers M. Brown, Susan E. Cole, Mirjana Maletic-Savatic, Thomas Gridley, Martin L. Basch, Andrew K. Groves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a915da6e44f04dd49a8deb28bda0521
https://doi.org/10.7554/elife.19921.015
https://doi.org/10.7554/elife.19921.015
The mammalian cochlea is a remarkable sensory organ, capable of perceiving sound over a range of 10(12) in pressure, and discriminating both infrasonic and ultrasonic frequencies in different species. The sensory hair cells of the mammalian cochlea a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca96f70664ca7590def76ff2132dfca
https://europepmc.org/articles/PMC4718162/
https://europepmc.org/articles/PMC4718162/