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Immunological analysis of the zinc-binding peptides of surface metalloproteinase (gp63) or Leishmania major.

Autor: Yang, D.¹, Rogers, M. V.², Brett, S. J.¹, Liew, F. Y.³

Publikováno v: Immunology. Apr93, Vol. 78 Issue 4, p582-585. 4p.

Immunological analysis of the zinc-binding peptides of surface metalloproteinase (gp63) of Leishmania major

Autor: Yang, D, Rogers, M V, Brett, S J, Liew, F Y

The surface metalloproteinase, gp63, is highly conserved and immunogenic. A peptide spanning the zinc-binding region of the molecule is immunogenic and can induce protective immunity in mice against Leishmania major infection. We report here that the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c747e0fcb3ad28ea595bc1f3ebbe7655
https://europepmc.org/articles/PMC1421896/

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Identification and characterization of host-protective T-cell epitopes of a major surface glycoprotein (gp63) from Leishmania major

Autor: Yang, D M, Rogers, M V, Liew, F Y

By using a series of overlapping synthetic peptides that cover more than 75% of the amino acid sequence of the major surface glycoprotein (gp63) from Leishmania major, 11 T-cell epitopes in CBA and BALB/c mice have been identified. Six of the peptide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c97f550080a21011f46e891ccefbda6b
https://europepmc.org/articles/PMC1384327/

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