Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Roger Xie"'
Publikováno v:
Journal of Applied Clinical Medical Physics
In this study, we evaluated the performance of an Elekta linac in the delivery of gated radiotherapy. Delivery accuracy was examined with an emphasis on the impact of using short gating windows (low monitor unit beam‐on segments) or long beam hold
Autor:
David P. Carney, Amy V. Lynch, Robert B. Perni, Pui Yee Ng, Jeremy S. Disch, Roger Xie, Michael R. Jirousek, Jill C. Milne, J. Joshua Smith, Lei Jin, Andre Iffland, Joseph J. Nunes, Jean Bemis, Siva Lavu, Chi B. Vu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:2350-2353
SIRT1 is an NAD+-dependent protein deacetylase that appears to produce beneficial effects on metabolic parameters such as glucose and insulin homeostasis. Activation of SIRT1 by resveratrol (1) has been shown to modulate insulin resistance, increase
Autor:
Wendy Choy, Kristine Israelian, J. Joshua Smith, Simon Schenk, Siva Lavu, David P. Carney, Olivier Boss, Philip D. Lambert, Lei Jin, David J. Gagne, David A. Sinclair, Michael R. Jirousek, Andre Iffland, Amy V. Lynch, Jean Bemis, Roger Xie, Robert B. Perni, Pui Yee Ng, Hongying Yang, Jill C. Milne, Jeremy S. Disch, Chi B. Vu, Peter J. Elliott, Jerrold M. Olefsky, Christoph H. Westphal, Heidi Galonek, Oliver Medvedik, Joseph J. Nunes
Publikováno v:
Nature. 450:712-716
Calorie restriction extends lifespan and produces a metabolic profile desirable for treating diseases of ageing such as type 2 diabetes1,2. SIRT1, an NAD+-dependent deacetylase, is a principal modulator of pathways downstream of calorie restriction t
Autor:
James R. Hauske, Roger Xie
Publikováno v:
Tetrahedron Letters. 41:10167-10170
The investigation of palladium-catalyzed alkoxyallylation of activated olefins, followed by ring-closing metathesis to synthesize functionalized seven-membered ring allyl ethers is described. The influence of the olefin substituents on the diastereos
Autor:
Roger Xie, James R. Hauske
Publikováno v:
ChemInform. 32
The investigation of palladium-catalyzed alkoxyallylation of activated olefins, followed by ring-closing metathesis to synthesize functionalized seven-membered ring allyl ethers is described. The influence of the olefin substituents on the diastereos