Zobrazeno 1 - 10
of 515
pro vyhledávání: '"Roger W, Beuerman"'
Autor:
Darren Shu Jeng Ting, Eunice Tze Leng Goh, Venkatesh Mayandi, Joanna M. F. Busoy, Thet Tun Aung, Mercy Halleluyah Periayah, Mario Nubile, Leonardo Mastropasqua, Dalia G. Said, Hla M. Htoon, Veluchamy Amutha Barathi, Roger W. Beuerman, Rajamani Lakshminarayanan, Imran Mohammed, Harminder S. Dua
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Bacterial keratitis (BK) is a major cause of corneal blindness globally. This study aimed to develop a novel class of antimicrobial therapy, based on human-derived hybrid host defense peptides (HyHDPs), for treating BK. HyHDPs were rationall
Externí odkaz:
https://doaj.org/article/b8964e8c144045dd99c424d45d86d9a4
Autor:
Darren Shu Jeng Ting, Imran Mohammed, Rajamani Lakshminarayanan, Roger W. Beuerman, Harminder S. Dua
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Sight is arguably the most important sense in human. Being constantly exposed to the environmental stress, irritants and pathogens, the ocular surface – a specialized functional and anatomical unit composed of tear film, conjunctival and corneal ep
Externí odkaz:
https://doaj.org/article/884c876046c4495898cbbdd11b0f356a
Myopia is the most common optical disorder in the world, and is on the rise in many countries, particularly in East Asia. The impact of myopia is evident as the driving force in the development of refractive surgery and of the spectacle and contact l
Autor:
Darren Shu Jeng Ting, Jianguo Li, Chandra S. Verma, Eunice T. L. Goh, Mario Nubile, Leonardo Mastropasqua, Dalia G. Said, Roger W. Beuerman, Rajamani Lakshminarayanan, Imran Mohammed, Harminder S. Dua
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background/Aim: Host defense peptides (HDPs) have the potential to provide a novel solution to antimicrobial resistance (AMR) in view of their unique and broad-spectrum antimicrobial activities. We had recently developed a novel hybrid HDP based on L
Externí odkaz:
https://doaj.org/article/65f70df69b1e420d94e11d23b971b8e6
Autor:
Zhidai Liu, Tingting Zhou, Xing Han, Tingyuan Lang, Shan Liu, Penghui Zhang, Haiyan Liu, Kexing Wan, Jie Yu, Liang Zhang, Liyan Chen, Roger W. Beuerman, Bin Peng, Lei Zhou, Lin Zou
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Abstract Background The altered concentrations of amino acids were found in the bone marrow or blood of leukemia patients. Metabolomics technology combining mathematical model of biomarkers could be used for assisting the diagnosis of pediatric acute
Externí odkaz:
https://doaj.org/article/2082bda4f4504c04a850da192c9d504c
Autor:
Mingjun Yuan, Song Lin Chua, Yang Liu, Daniela I. Drautz-Moses, Joey Kuok Hoong Yam, Thet Tun Aung, Roger W. Beuerman, May Margarette Santillan Salido, Stephan C. Schuster, Choon-Hong Tan, Michael Givskov, Liang Yang, Thomas E. Nielsen
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 3059-3069 (2018)
Antibiotic resistance threatens effective treatment of microbial infections globally. This situation has spurred the hunt for new antimicrobial compounds in both academia and the pharmaceutical industry. Here, we report how the widely used antitumor
Externí odkaz:
https://doaj.org/article/753a8d0395f842239fb8a40c6d273c36
Autor:
Darren Shu Jeng Ting, Roger W. Beuerman, Harminder S. Dua, Rajamani Lakshminarayanan, Imran Mohammed
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The golden era of antibiotics, heralded by the discovery of penicillin, has long been challenged by the emergence of antimicrobial resistance (AMR). Host defense peptides (HDPs), previously known as antimicrobial peptides, are emerging as a group of
Externí odkaz:
https://doaj.org/article/93d36010b0bf43adb4584d231ff490c2
Autor:
Leena Latonen, Ebrahim Afyounian, Antti Jylhä, Janika Nättinen, Ulla Aapola, Matti Annala, Kati K. Kivinummi, Teuvo T. L. Tammela, Roger W. Beuerman, Hannu Uusitalo, Matti Nykter, Tapio Visakorpi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Understanding of molecular events in cancer requires proteome-level characterisation. Here, proteome profiling of patient samples representing primary and progressed prostate cancer enables the authors to identify pathway alterations that are not ref
Externí odkaz:
https://doaj.org/article/61f749925834414ebb92c52acbc5d9a6
Publikováno v:
ACS Omega, Vol 3, Iss 3, Pp 2498-2507 (2018)
Externí odkaz:
https://doaj.org/article/b94a28360135480bb5a461a41735a3e3
Autor:
Qiao Fan, Virginie J. M. Verhoeven, Robert Wojciechowski, Veluchamy A. Barathi, Pirro G. Hysi, Jeremy A. Guggenheim, René Höhn, Veronique Vitart, Anthony P. Khawaja, Kenji Yamashiro, S Mohsen Hosseini, Terho Lehtimäki, Yi Lu, Toomas Haller, Jing Xie, Cécile Delcourt, Mario Pirastu, Juho Wedenoja, Puya Gharahkhani, Cristina Venturini, Masahiro Miyake, Alex W. Hewitt, Xiaobo Guo, Johanna Mazur, Jenifer E. Huffman, Katie M. Williams, Ozren Polasek, Harry Campbell, Igor Rudan, Zoran Vatavuk, James F. Wilson, Peter K. Joshi, George McMahon, Beate St Pourcain, David M. Evans, Claire L. Simpson, Tae-Hwi Schwantes-An, Robert P. Igo, Alireza Mirshahi, Audrey Cougnard-Gregoire, Céline Bellenguez, Maria Blettner, Olli Raitakari, Mika Kähönen, Ilkka Seppälä, Tanja Zeller, Thomas Meitinger, Janina S. Ried, Christian Gieger, Laura Portas, Elisabeth M. van Leeuwen, Najaf Amin, André G. Uitterlinden, Fernando Rivadeneira, Albert Hofman, Johannes R. Vingerling, Ya Xing Wang, Xu Wang, Eileen Tai-Hui Boh, M. Kamran Ikram, Charumathi Sabanayagam, Preeti Gupta, Vincent Tan, Lei Zhou, Candice E. H. Ho, Wan’e Lim, Roger W. Beuerman, Rosalynn Siantar, E-Shyong Tai, Eranga Vithana, Evelin Mihailov, Chiea-Chuen Khor, Caroline Hayward, Robert N. Luben, Paul J. Foster, Barbara E. K. Klein, Ronald Klein, Hoi-Suen Wong, Paul Mitchell, Andres Metspalu, Tin Aung, Terri L. Young, Mingguang He, Olavi Pärssinen, Cornelia M. van Duijn, Jie Jin Wang, Cathy Williams, Jost B. Jonas, Yik-Ying Teo, David A. Mackey, Konrad Oexle, Nagahisa Yoshimura, Andrew D. Paterson, Norbert Pfeiffer, Tien-Yin Wong, Paul N. Baird, Dwight Stambolian, Joan E. Bailey Wilson, Ching-Yu Cheng, Christopher J. Hammond, Caroline C. W. Klaver, Seang-Mei Saw, Consortium for Refractive Error and Myopia (CREAM)
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
This report by the Consortium for Refractive Error and Myopia uses gene-environment-wide interaction study (GEWIS) to identify genetic loci that affect environmental influence in myopia development, and identifies ethnic specific genetic loci that at
Externí odkaz:
https://doaj.org/article/b0563139c510416e9a4da61510e1f5d4