Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Roger V, Ortines"'
Autor:
Oren Gordon, Dustin A. Dikeman, Roger V. Ortines, Yu Wang, Christine Youn, Mohammed Mumtaz, Nicholas Orlando, Jeffrey Zhang, Aman M. Patel, Ethan Gough, Amit Kaushik, Eric L. Nuermberger, Anna M. Upton, Nader Fotouhi, Lloyd S. Miller, Nathan K. Archer
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Staphylococcus aureus is an important cause of various infections in humans, including bacteremia, skin and soft tissue infections, and infections associated with implanted medical devices. The emergence of hospital- and community-acquired m
Externí odkaz:
https://doaj.org/article/d6e58e0732d248c5ad23795e60ded5ae
Autor:
Francisco Romero Pastrana, John M. Thompson, Marjolein Heuker, Hedzer Hoekstra, Carly A. Dillen, Roger V. Ortines, Alyssa G. Ashbaugh, Julie E. Pickett, Matthijs D. Linssen, Nicholas M. Bernthal, Kevin P. Francis, Girbe Buist, Marleen van Oosten, Gooitzen M. van Dam, Daniel L. J. Thorek, Lloyd S. Miller, Jan Maarten van Dijl
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 262-272 (2018)
Staphylococcus aureus infections are a major threat in healthcare, requiring adequate early-stage diagnosis and treatment. This calls for novel diagnostic tools that allow noninvasive in vivo detection of staphylococci. Here we performed a preclinica
Externí odkaz:
https://doaj.org/article/b3948013660441b29da4311a15413d71
Autor:
Lloyd S. Miller, Eric M. Wier, Brittany Pielstick, Christine Youn, Martin P. Alphonse, Gaofeng Wang, Nathan K. Archer, Ang Li, Evan Sweren, Luis A. Garza, Mayumi Asada, Chenyi Lyu, Maria Daskam, Roger V. Ortines, Chase Hintelmann
Publikováno v:
Journal of Cellular and Molecular Medicine
Fibrosis is a major health burden across diseases and organs. To remedy this, we study wound‐induced hair follicle neogenesis (WIHN) as a model of non‐fibrotic healing that recapitulates embryogenesis for de novo hair follicle morphogenesis after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488aad45948069924c9610cdb1a1449a
http://europepmc.org/articles/PMC8572775
http://europepmc.org/articles/PMC8572775
Autor:
Roger V. Ortines, Lloyd S. Miller, Carly A. Dillen, Jeffrey Zhang, Nathan K. Archer, Martin P. Alphonse, Haiyun Liu, John M. Thompson, Dustin Dikeman, Sophie E. Kim, Yu Wang, Christian Falgons, Alyssa G. Ashbaugh, Nicole E. Ackerman, Daniel P. Joyce
Publikováno v:
J Orthop Res
Orthopedic implant-associated infection (OIAI) is a major complication that leads to implant failure. In preclinical models of Staphylococcus aureus OIAI, osteomyelitis and septic arthritis, interleukin-1α (IL-1α), IL-1β, and tumor necrosis factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c837ccb676b48d022cca33617913bff
https://doi.org/10.1002/jor.24608
https://doi.org/10.1002/jor.24608
Autor:
Xintong Dong, Nathachit Limjunyawong, Elizabeth I. Sypek, Gaofeng Wang, Roger V. Ortines, Christine Youn, Martin P. Alphonse, Dustin Dikeman, Yu Wang, Mark Lay, Ruchita Kothari, Chirag Vasavda, Priyanka Pundir, Loyal Goff, Lloyd S. Miller, Wuyuan Lu, Luis A. Garza, Brian S. Kim, Nathan K. Archer, Xinzhong Dong
Publikováno v:
Immunity. 55:1645-1662.e7
Healthy skin maintains a diverse microbiome and a potent immune system to fight off infections. Here, we discovered that the epithelial-cell-derived antimicrobial peptides defensins activated orphan G-protein-coupled receptors (GPCRs) Mrgpra2a/b on n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0624e4cff04083c6cac75a49275a3b
https://doi.org/10.1016/j.immuni.2022.06.021
https://doi.org/10.1016/j.immuni.2022.06.021
Autor:
Jan Maarten van Dijl, Daniel L.J. Thorek, Marleen van Oosten, Lloyd S. Miller, Carly A. Dillen, Francisco Romero Pastrana, Hedzer Hoekstra, Alyssa G. Ashbaugh, Gooitzen M. van Dam, Marjolein Heuker, Kevin P. Francis, Julie E. Pickett, John M. Thompson, Nicholas M. Bernthal, Matthijs D. Linssen, Girbe Buist, Roger V. Ortines
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 262-272 (2018)
Virulence, 9(1), 262-272. Taylor & Francis Group
Virulence
Virulence, vol 9, iss 1
Virulence, 9(1), 262-272. Taylor & Francis Group
Virulence
Virulence, vol 9, iss 1
Staphylococcus aureus infections are a major threat in healthcare, requiring adequate early-stage diagnosis and treatment. This calls for novel diagnostic tools that allow noninvasive in vivo detection of staphylococci. Here we performed a preclinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fad9c69b0244e96a754cfa58f27bc5e
https://doaj.org/article/b3948013660441b29da4311a15413d71
https://doaj.org/article/b3948013660441b29da4311a15413d71
Autor:
Kristine Nguyen, Yu Wang, Guangping Sun, Eric M. Wier, Alexander C. Klimowicz, Alina I. Marusina, Jack C. Otterson, Joshua D. Milner, Lee Ann T. Marcello, Roger V. Ortines, Alexander A. Merleev, George Denny, Dustin Dikeman, Jay S. Fine, Qi Liu, Emily Zhang, Emanual Michael Maverakis, Lloyd S. Miller, Christine Youn, Garrett J. Patrick, Yan Zhang, Martin P. Alphonse, Haiyun Liu, Momina Mazhar, Danh C. Do, Meera Ramanujam, Nathan K. Archer, Advaitaa Ravipati, Ernest L. Raymond, Peisong Gao, Sabrina J. Nolan, Robert J. Miller, Diane Mierz, Gary O. Caviness, Raphaela Goldbach-Mansky, Carly A. Dillen, Luis A. Garza
Publikováno v:
J Clin Invest
The Journal of clinical investigation, vol 131, iss 5
The Journal of clinical investigation, vol 131, iss 5
IgE induced by type 2 immune responses in atopic dermatitis is implicated in the progression of atopic dermatitis to other allergic diseases, including food allergies, allergic rhinitis, and asthma. However, the keratinocyte-derived signals that prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e1319c539f7f589bf052e9683f6253
https://doi.org/10.1172/jci143334
https://doi.org/10.1172/jci143334
Autor:
Dustin Dikeman, Sophie E. Kim, Martin P. Alphonse, Haiyun Liu, John M. Thompson, Nathan K. Archer, Roger V. Ortines, Nicole E. Ackerman, Abigail A. Thomas, Daniel P. Joyce, Yu Wang, Jeffrey Zhang, Carly A. Dillen, Roger D. Plaut, Lloyd S. Miller
Publikováno v:
J Orthop Res
C-C motif chemokine receptor 2 (CCR2) is an important mediator of myeloid cell chemotaxis during inflammation and infection. Myeloid cells such as monocytes, macrophages, and neutrophils contribute to host defense during orthopedic implant-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916dd5c11c17b630cd66ce18b641e6a6
https://pubmed.ncbi.nlm.nih.gov/33713394
https://pubmed.ncbi.nlm.nih.gov/33713394
Autor:
Dustin Dikeman, Yu Wang, Brian S. Kim, Roger V. Ortines, Xinzhong Dong, Gaofeng Wang, Martin P. Alphonse, Nathachit Limjunyawong, Loyal A. Goff, Luis A. Garza, Elizabeth Sypek, Mark Lay, Priyanka Pundir, Wuyuan Lu, Christine Youn, Lloyd S. Miller, Xintong Dong, Nathan K. Archer
Publikováno v:
SSRN Electronic Journal.
Healthy skin maintains a diverse microbiome and a potent immune system to fight off infections. Here, we discovered that epithelial cell-derived antimicrobial peptides defensins activate orphan GPCRs Mrgpra2a/b on neutrophils. This signaling axis is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d4727774925de6ecb5f2ab356f8ba36
https://doi.org/10.2139/ssrn.3885989
https://doi.org/10.2139/ssrn.3885989
Autor:
Carly A. Dillen, Mark C. Marchitto, Dustin Dikeman, Roger V. Ortines, Nathan K. Archer, S. Lee, Lloyd S. Miller, Martin P. Alphonse, Christine Youn, Advaitaa Ravipati, H. Liu, S. Sarah Cai, N.A. Orlando, Yu Wang, Garrett J. Patrick, Sabrina J. Nolan, Robert J. Miller
Publikováno v:
J Invest Dermatol
Signal transducer and activator of transcription 3 (STAT3) is important for psoriasis pathogenesis because STAT3 signaling downstream of IL-6, IL-21, IL-22, and IL-23 contributes to T helper type 17 cell development and because transgenic mice with k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756f9ee75f252679bb2b68dc1a8a5ead
https://doi.org/10.1016/j.jid.2021.09.012
https://doi.org/10.1016/j.jid.2021.09.012