Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Roger Shapiro"'
Autor:
Wonderful T. Choga, Gobuiwang Khilly Kurusa (Gasenna), James Emmanuel San, Tidimalo Ookame, Irene Gobe, Mohammed Chand, Badisa Phafane, Kedumetse Seru, Patience Matshosi, Boitumelo Zuze, Nokuthula Ndlovu, Teko Matsuru, Dorcas Maruapula, Ontlametse T. Bareng, Kutlo Macheke, Lesego Kuate-Lere, Labapotswe Tlale, Onalethata Lesetedi, Modiri Tau, Mpaphi B. Mbulawa, Pamela Smith-Lawrence, Mogomotsi Matshaba, Roger Shapiro, Joseph Makhema, Darren P. Martin, Tulio de Oliveira, Richard J. Lessells, Shahin Lockman, Simani Gaseitsiwe, Sikhulile Moyo
Publikováno v:
International Journal of Infectious Diseases, Vol 138, Iss , Pp 91-96 (2024)
We investigated intra-host genetic evolution using two SARS-CoV-2 isolates from a fully vaccinated (primary schedule x2 doses of AstraZeneca plus a booster of Pfizer), >70-year-old woman with a history of lymphoma and hypertension who presented a SAR
Externí odkaz:
https://doaj.org/article/a4563b67ede2463ca061c016f76e974e
Autor:
Kabo Baruti, Bonolo B. Phinius, Basetsana Phakedi, Gorata Mpebe, Wonderful Choga, Lynnette Bhebhe, Graceful Mulenga, Natasha O. Moraka, Tsholofelo Ratsoma, Molly Pretorius-Holme, Joseph Makhema, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Mosimanegape Jongman, Motswedi Anderson, Simani Gaseitsiwe
Publikováno v:
Journal of Infection and Public Health, Vol 16, Iss 11, Pp 1736-1741 (2023)
Background: Approximately 15–20 million people worldwide are infected with hepatitis delta virus (HDV), which is approximately 5 % of people with chronic hepatitis B virus (HBV). Sub-Saharan Africa has high HDV prevalence, leading to worse clinical
Externí odkaz:
https://doaj.org/article/dd66fdf5db2c49a28d573a6c8fee0b9e
Autor:
Natasha O. Moraka, Wonderful T. Choga, Marea N. Pema, Moses Kudzai Chawawa, Irene Gobe, Margaret Mokomane, Ontlametse T. Bareng, Lynette Bhebhe, Nametso Kelentse, Graceful Mulenga, Molly Pretorius Holme, Terence Mohammed, Catherine K. Koofhethile, Joseph M. Makhema, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract We used HIV-1C sequences to predict (in silico) resistance to 33 known broadly neutralizing antibodies (bnAbs) and evaluate the different HIV-1 Env characteristics that may affect virus neutralization. We analyzed proviral sequences from adu
Externí odkaz:
https://doaj.org/article/34cd02c202c244d98df4161bb39f3c8a
Autor:
Motswedi Anderson, Thabo Mangogola, Bonolo B. Phinius, Gorata Mpebe, Christopher O. Aimakhu, Wonderful T. Choga, Basetsana Phakedi, Lynnette N. Bhebhe, Doreen Ditshwanelo, Kabo Baruti, Linda Mpofu-Dobo, Lebogang Othusitse, Tsholofelo Ratsoma, Tendani Gaolathe, Joseph Makhema, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Microorganisms, Vol 12, Iss 6, p 1207 (2024)
(1) Background: we determined the prevalence of the hepatitis B virus (HBV) amongst people without human immunodeficiency virus (HIV) in rural and peri-urban areas in Botswana. (2) Methods: We screened for the hepatitis B surface antigen (HBsAg) from
Externí odkaz:
https://doaj.org/article/ea3db4e9939c447982af0187a751846f
Autor:
Ontlametse T. Bareng, Sikhulile Moyo, Mbatshi Mudanga, Kagiso Sebina, Catherine K. Koofhethile, Wonderful T. Choga, Natasha O. Moraka, Dorcas Maruapula, Irene Gobe, Modisa S. Motswaledi, Rosemary Musonda, Bornapate Nkomo, Dinah Ramaabya, Tony Chebani, Penny Makuruetsa, Joseph Makhema, Roger Shapiro, Shahin Lockman, Simani Gaseitsiwe
Publikováno v:
Viruses, Vol 16, Iss 5, p 720 (2024)
We evaluated subsequent virologic outcomes in individuals experiencing low-level virem ia (LLV) on dolutegravir (DTG)-based first-line antiretroviral therapy (ART) in Botswana. We used a national dataset from 50,742 adults who initiated on DTG-based
Externí odkaz:
https://doaj.org/article/9a9fbac7f29e4b949b9064b7914cbad8
Autor:
Rebecca Luckett, Doreen Ramogola-Masire, Devon A. Harris, Annika Gompers, Kelebogile Gaborone, Lorato Mochoba, Lapelo Ntshese, Anikie Mathoma, Maduke Kula, Roger Shapiro, Elysia Larson
Publikováno v:
Frontiers in Global Women's Health, Vol 4 (2024)
BackgroundThe WHO strategy for cervical cancer elimination strives to achieve 70% coverage with high-performance cervical screening. While few low- and middle-income countries have achieved this, high-risk human papillomavirus (hrHPV) self-testing cr
Externí odkaz:
https://doaj.org/article/5381c322fdb34eb9a54c4c75ba3a10c7
Autor:
Maureen Sakoi-Mosetlhi, Gbolahan Ajibola, Roxanna Haghighat, Oganne Batlang, Kenneth Maswabi, Molly Pretorius-Holme, Kathleen M Powis, Shahin Lockman, Joseph Makhema, Mathias Litcherfeld, Daniel R Kuritzkes, Roger Shapiro
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0299942 (2024)
IntroductionMonthly intravenous infusion of broadly neutralizing monoclonal antibodies may be an attractive alternative to daily oral antiretroviral treatment for children living with HIV. However, acceptability among caregivers remains unknown.Metho
Externí odkaz:
https://doaj.org/article/65c270a1506149dfb1d3093e11593302
Autor:
Boitumelo J. L. Zuze, Botshelo T. Radibe, Wonderful T. Choga, Ontlametse T. Bareng, Natasha O. Moraka, Dorcas Maruapula, Kedumetse Seru, Patrick Mokgethi, Baitshepi Mokaleng, Nokuthula Ndlovu, Nametso Kelentse, Molly Pretorius-Holme, Roger Shapiro, Shahin Lockman, Joseph Makhema, Vlad Novitsky, Kaelo K. Seatla, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT There are limited data on the prevalence of fostemsavir (FTR) resistance-associated polymorphisms in people with HIV in Botswana. We sought to determine the prevalence of FTR resistance-associated polymorphisms in HIV-1 subtype C sequences f
Externí odkaz:
https://doaj.org/article/8a3484c8f0984aef98f28951e867c1e8
Autor:
Wonderful T. Choga, Samantha L. Letsholo, Chandapiwa Marobela‐Raborokgwe, Irene Gobe, Mbatshi Mazwiduma, Dorcas Maruapula, John Rukwava, Mary Gorettie Binta, Boitumelo J. L Zuze, Legodile Koopile, Kedumetse Seru, Patience Motshosi, Ontlametse Thato Bareng, Botshelo Radibe, Pamela Smith‐Lawrence, Kutlo Macheke, Lesego Kuate‐Lere, Modisa S. Motswaledi, Mpaphi B. Mbulawa, Mogomotsi Matshaba, Kereng V. Masupu, Shahin Lockman, Roger Shapiro, Joseph Makhema, Mosepele Mosepele, Simani Gaseitsiwe, Sikhulile Moyo
Publikováno v:
Veterinary Medicine and Science, Vol 9, Iss 4, Pp 1465-1472 (2023)
Abstract We sought to investigate whether SARS‐CoV‐2 was present, and to perform full‐length genomic sequencing, in a 5‐year‐old male crossbreed dog from Gaborone, Botswana that presented overt clinical signs (flu‐like symptoms, dry hacki
Externí odkaz:
https://doaj.org/article/92e2601e0fa74b2cb40aab8c50df3dee
Autor:
Sikhulile Moyo, Doreen Ramogola-Masire, Natasha O. Moraka, Leabaneng Tawe, Farzad Noubary, Kesego Motsumi, Godiraone Manowe, Boitumelo Zuze, Botshelo Radibe, Faith T. T. Hungwe, Terence Mohammed, Comfort Maphorisa, Roger Shapiro, Simani Gaseitsiwe, Rebecca Luckett
Publikováno v:
Infectious Agents and Cancer, Vol 18, Iss 1, Pp 1-7 (2023)
Abstract Background Low- and middle-income countries (LMICs) account for nearly 85% of the global cervical cancer burden, yet have the least access to high-performance screening. International guidelines recommend human papillomavirus testing (HPV) a
Externí odkaz:
https://doaj.org/article/a46cba6b2ee64e1d90fc60e77e0be67f