Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Roger Le Verge"'
Autor:
Michel Pinaud, François Chevanne, Pascal Le Corre, Jean-Marc Malinovsky, Roger Le Verge, G. Dollo, Alain Péron
Publikováno v:
International Journal of Pharmaceutics. 272:109-119
To assess the prolongation of epidural bupivacaine by hyaluronic acid viscous formulations we designed a cross-over study in rabbits. Different doses of bupivacaine (3 or 6 mg) either as a solution (bupivacaine hydrochloride), or as viscous formulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa0881e98b00fb6dc54c27cc3b68a54
https://doi.org/10.1016/j.ijpharm.2003.12.002
https://doi.org/10.1016/j.ijpharm.2003.12.002
Autor:
Roger Le Verge, Marc Gentili, Claude Ecoffey, Pascal Le Corre, Jean-Pierre Estebe, Moulinoux Jp
Publikováno v:
Canadian Journal of Anaesthesia. 49:690-693
Purpose: The aim of this study was to evaluate the effect of different durations of local anesthetic neural blockade on hyperalgesia after carrageenan infiltration in a rat model. Methods: Inflammation was obtained by injection of carrageenan in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3feda600c9e6c3350b289668fde8e6
https://doi.org/10.1007/bf03017447
https://doi.org/10.1007/bf03017447
Autor:
Claude Ecoffey, Pascal Le Corre, Roger Le Verge, G. Dollo, Jean-Pierre Estebe, François Chevanne
Publikováno v:
European Journal of Pharmaceutical Sciences. 13:319-323
The purpose of this study was to examine if lidocaine diffusion across an endotracheal tube cuff could improve post-operative tolerance, especially sore throat. The in vitro release of lidocaine from tube cuffs filled with different lidocaine formula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818116756a2ef819f929df1d0cfa004f
https://doi.org/10.1016/s0928-0987(01)00119-1
https://doi.org/10.1016/s0928-0987(01)00119-1
Autor:
Hélène Jouan, Roselyne Primault, André Jestin, Roger Le Verge, Anne-Marie Torché, Emmanuel Albina, Pascal Le Corre
Publikováno v:
International Journal of Pharmaceutics. 201:15-27
We investigated the ability of pig ileal Peyer's patch segments to transport intestinal poly (D,L-lactide-co-glycolide) microspheres (PLGA MS) from intestinal lumen across the mucosae using in situ and ex vivo segments with confocal laser scanning mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774a90c04da19e9b1b28c45d21585573
https://doi.org/10.1016/s0378-5173(00)00364-1
https://doi.org/10.1016/s0378-5173(00)00364-1
Publikováno v:
European Journal of Pharmaceutical Sciences. 9:79-84
The biopharmaceutics of yohimbine (YO) and the pharmacokinetics of 10-hydroxy-yohimbine (10-OH-YO) and 11-hydroxy-yohimbine (11-OH-YO) were investigated in healthy subjects following i.v. (5 mg) and oral (8 mg) dosing. One subject was found as a slow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb31cd31d6d0ad1465ebc77bd7382871
https://doi.org/10.1016/s0928-0987(99)00046-9
https://doi.org/10.1016/s0928-0987(99)00046-9
Autor:
Jean-Louis Burgot, Marcel Bertault, Pascal Le Corre, François Chevanne, Chollet Marylene, Roger Le Verge, G. Dollo
Publikováno v:
Journal of Pharmaceutical Sciences. 88:889-895
Inclusion complexes between beta-cyclodextrin derivatives and 1, 2-dithione-3-thiones were studied in aqueous solution and in the solid state. Phase solubility study was used to evaluate the complexation in solution, at 37 degrees C, of three cyclode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7180991bec2d764cc04050d0eb4e1ec1
https://doi.org/10.1021/js990067o
https://doi.org/10.1021/js990067o
Publikováno v:
Journal of Controlled Release. 58:289-301
The phagocytosis of fluorescent poly(D,L-lactide-co-glycolide) microspheres by fresh and frozen pig alveolar macrophages was investigated by optical microscopy on adherent cell culture and by flow cytometry with cell suspension. The kinetic of phagoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69966ad0051f6728d98f23e473f163d4
https://doi.org/10.1016/s0168-3659(98)00166-7
https://doi.org/10.1016/s0168-3659(98)00166-7
Publikováno v:
International Journal of Pharmaceutics. 164:11-19
The effect of a new modified β -cyclodextrin derivative, sulfobutylether7- β -cyclodextrin (SBE7- β CD) on the biopharmaceutics of local anesthetic bupivacaine (BVC) was studied in a rabbit sciatic model. Phase-solubility study revealed the format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f6b4f2ce202e50acda2ab71752e0f3f
https://doi.org/10.1016/s0378-5173(97)00365-7
https://doi.org/10.1016/s0378-5173(97)00365-7
Publikováno v:
International Journal of Pharmaceutics. 136:165-174
The inclusion complex-forming abilities of five local anaesthetics of the amide-type (LAs), bupivacaine (BVC), etidocaine (EDC), lidocaine (LDC), mepivacaine (MVC) and prilocaine (PLC), with three cyclodextrins (CDs), β-cyclodextrin (βCD) and its a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::641c7e21bac986f842a43a20256edc69
https://doi.org/10.1016/0378-5173(96)04512-7
https://doi.org/10.1016/0378-5173(96)04512-7
Publikováno v:
International Journal of Pharmaceutics. 134:37-46
The aim of using opioid drugs such as morphine in chronic pain is optimal pain relief with a minimum of side effects. After the discovery that opioids could produce analgesia when administered intrathecally or extradurally, there has been particular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcdbeaab26cbcb3db7917390c5a25e8a
https://doi.org/10.1016/0378-5173(95)04402-7
https://doi.org/10.1016/0378-5173(95)04402-7