Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Roger Lane"'
Autor:
Robert C. Bucelli, Manjit McNeill, Shafeeq Ladha, Angela Genge, Stephanie Fradette, Ivan Nestorov, John Ravits, Philip Van Damme, Roger Lane, Christopher J McDermott, Jonathan Glass, Merit Cudkowicz, Laura Fanning, C. Frank Bennett, Heiko Runz, Ih Chang, Hani Houshyar, Toby A. Ferguson, Alfred Sandrock, Alan Pestronk, Danielle Graham, Timothy M. Miller, Randall G. Trudell, Nazem Atassi, Peter M. Andersen, François Salachas, Nicholas J. Maragakis, Albert L. Ludolph, Pamela J. Shaw, Lorne Zinman, Alexander McCampbell
Publikováno v:
New England Journal of Medicine. 383:109-119
Background Tofersen is an antisense oligonucleotide that mediates the degradation of superoxide dismutase 1 (SOD1) messenger RNA to reduce SOD1 protein synthesis. Intrathecal administratio...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd89d37b574703a54dc8fa55df6264a4
https://doi.org/10.1056/nejmoa2003715
https://doi.org/10.1056/nejmoa2003715
Autor:
Roger Lane
Lane here illuminates the African-American experience through a close look at a single city, once the metropolitan headquarters of black America, now typical of many. He recognizes that urban history offers more clues, both to modern accomplishments
Publikováno v:
Advances in Human Aspects of Transportation: Part II.
Integrating a new system in the air traffic control system is always a big challenge, in particular when the new system impacts the controller human machine interface (HMI). The Controller Pilot DataLink Communication system for airport controller is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af3374233444e39ff5ade24efe0738d4
https://doi.org/10.54941/ahfe100711
https://doi.org/10.54941/ahfe100711
Autor:
Timothy, Miller, Merit, Cudkowicz, Pamela J, Shaw, Peter M, Andersen, Nazem, Atassi, Robert C, Bucelli, Angela, Genge, Jonathan, Glass, Shafeeq, Ladha, Albert L, Ludolph, Nicholas J, Maragakis, Christopher J, McDermott, Alan, Pestronk, John, Ravits, François, Salachas, Randall, Trudell, Philip, Van Damme, Lorne, Zinman, C Frank, Bennett, Roger, Lane, Alfred, Sandrock, Heiko, Runz, Danielle, Graham, Hani, Houshyar, Alexander, McCampbell, Ivan, Nestorov, Ih, Chang, Manjit, McNeill, Laura, Fanning, Stephanie, Fradette, Toby A, Ferguson
Publikováno v:
The New England journal of medicine. 383(2)
Tofersen is an antisense oligonucleotide that mediates the degradation of superoxide dismutase 1 (SOD1) messenger RNA to reduce SOD1 protein synthesis. Intrathecal administration of tofersen is being studied for the treatment of amyotrophic lateral s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60508a8fa4e2c3ceebe60cab1d91953b
https://pubmed.ncbi.nlm.nih.gov/32704069
https://pubmed.ncbi.nlm.nih.gov/32704069
Autor:
C. Frank Bennett, Roger Lane
Publikováno v:
Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease ISBN: 9780128139554
Advances in human genetics and neurosciences have elucidated the fundamental mechanisms underlying many inherited neurological diseases and are providing detailed molecular insights into the causes of sporadic neurological diseases, yet disease-modif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd005921e46492843904376b9a23df94
https://doi.org/10.1016/b978-0-12-813955-4.00017-9
https://doi.org/10.1016/b978-0-12-813955-4.00017-9
Autor:
Blair R. Leavitt, Carsten Saft, Edward J. Wild, C. Frank Bennett, Daniel A. Norris, Josef Priller, Holly Kordasiewicz, Christian Czech, Bernhard Landwehrmeyer, Roger Lane, Scott Schobel, Hugh Rickards, Irene Gerlach, Anne Smith, Tiffany L. Baumann, Roger A. Barker, D Craufurd, Eric E. Swayze, Sarah J. Tabrizi, Anne Elizabeth Rosser
Publikováno v:
Clinical therapeutics.
Background HD is an autosomal dominant neurodegenerative disease caused by CAG repeat expansion in the HTT gene resulting in polyglutamine expansion in the mutant huntingtin protein (mHTT) with a toxic gain-of-function disease mechanism. No disease-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cd64c90089d88f1c93f6d8efacebf6b
https://doi.org/10.1136/jnnp-2018-ehdn.261
https://doi.org/10.1136/jnnp-2018-ehdn.261
Autor:
C. Frank Bennett, Tiffany L. Baumann, Holly B. Kordasiewicz, Marc Gleichmann, Anne Smith, Daniel A. Norris, Roger Lane
Publikováno v:
Methods in Molecular Biology ISBN: 9781493978243
Advances in molecular biology and genetics have been used to elucidate the fundamental genetic mechanisms underlying central nervous system (CNS) diseases, yet disease-modifying therapies are currently unavailable for most CNS conditions. Antisense o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::598b79834a8796859dff8c8aeb75e850
https://doi.org/10.1007/978-1-4939-7825-0_23
https://doi.org/10.1007/978-1-4939-7825-0_23
Autor:
Roger, Lane
Publikováno v:
The Indian Medical Gazette
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9a3da8011b4313a16aca4527b465d71
https://pubmed.ncbi.nlm.nih.gov/29015602
https://pubmed.ncbi.nlm.nih.gov/29015602
Autor:
Anne Smith, Holly Kordasiewicz, C. Frank Bennett, Niels Andreasen, Daniel A. Norris, Timothy M. Miller, Catherine J. Mummery, Laurence Mignon, Padma Kumar Narayanan, Bethany Fitzsimmons, Roger Lane, Eric E. Swayze
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::063a16fcd6e15813212ea0bb0e9b8762
https://doi.org/10.1016/j.jalz.2017.07.242
https://doi.org/10.1016/j.jalz.2017.07.242