Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Roger L. Miesfeld"'
Autor:
Jun Isoe, Carter J. Simington, Max E. Oscherwitz, Alyssa J. Peterson, Alberto A. Rascón, Brooke B. Massani, Roger L. Miesfeld, Michael A. Riehle
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-24 (2023)
Abstract Background Up to 40% of the world population live in areas where mosquitoes capable of transmitting the dengue virus, including Aedes aegypti, coexist with humans. Understanding how mosquito egg development and oviposition are regulated at t
Externí odkaz:
https://doaj.org/article/bfe5d70e980e4c1e9d86bdb4fe977f43
Autor:
Brooke Beam Massani, Roger L. Miesfeld, Peterson Aj, Oscherwitz Me, Jun Isoe, Alberto A. Rascón, Simington Cj
Up to 40% of the world population now live in areas where dengue mosquito vectors coexist with humans. Aedes aegypti are vectors for zoonotic diseases that affect hundreds of millions of individuals per year globally. We recently identified the eggsh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc2c60b4eb15d1766beca03d62bde31
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18150 (2011)
One of the early events in midgut epithelial cells of Aedes aegypti mosquitoes is the dynamic reorganization of rough endoplasmic reticulum (RER) whorl structures coincident with the onset of blood meal digestion. Based on our previous studies showin
Externí odkaz:
https://doaj.org/article/53857e8892d247b5881f7c9addc0341a
Autor:
Lauren E. Koch, Roger L. Miesfeld, Brooke Beam Massani, Heidi E. Brown, Yurika E. Isoe, Alberto A. Rascón, Jun Isoe
Publikováno v:
PLoS Biology
PLoS Biology, Vol 17, Iss 1, p e3000068 (2019)
PLoS Biology, Vol 17, Iss 1, p e3000068 (2019)
Mosquito-borne diseases are responsible for several million human deaths annually around the world. One approach to controlling mosquito populations is to disrupt molecular processes or antagonize novel metabolic targets required for the production o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8aecc269a64cf744bfbd3abcad1b01
https://doi.org/10.1371/journal.pbio.3000068
https://doi.org/10.1371/journal.pbio.3000068
Publikováno v:
Insect Biochemistry and Molecular Biology. 43:732-739
We have previously shown that defects in COPI coatomer proteins cause 80% mortality in blood fed Aedes aegypti mosquitoes by 96 hr post-feeding. In this study we show that similar deficiencies in COPII and clathrin mediated vesicle transport do not d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33573fcd53d35908834c0b91052cec33
https://doi.org/10.1016/j.ibmb.2013.05.005
https://doi.org/10.1016/j.ibmb.2013.05.005
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:5177-5181
A collection of Golgicide A (GCA) analogs has been synthesized and evaluated in larval and adult mosquito assays. Commercially available GCA is a mixture of four compounds. One enantiomer (GCA-2) of the major diastereomer in this mixture was shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb08dfdfab8a5dd58d96105544d71d01
https://doi.org/10.1016/j.bmcl.2012.06.076
https://doi.org/10.1016/j.bmcl.2012.06.076
Publikováno v:
Journal of Insect Physiology. 56:1040-1049
In order to understand at the tissue level how Aedes aegypti copes with toxic ammonia concentrations that result from the rapid metabolism of blood meal proteins, we investigated the incorporation of (15)N from (15)NH(4)Cl into amino acids using an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483574a7dbf66b225f6c666e7bcea404
https://doi.org/10.1016/j.jinsphys.2010.02.016
https://doi.org/10.1016/j.jinsphys.2010.02.016
Autor:
William C. Black, Ken E. Olson, Roger L. Miesfeld, Jun Isoe, Doug E. Brackney, Brian D. Foy, Jorge Zamora
Publikováno v:
Journal of Insect Physiology. 56:736-744
Aedes aegypti utilizes blood for energy production, egg maturation and replenishment of maternal reserves. The principle midgut enzymes responsible for bloodmeal digestion are endoproteolytic serine-type proteases within the S1.A subfamily. While the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f737515f45128637ae5761afcf7f0b
https://doi.org/10.1016/j.jinsphys.2010.01.003
https://doi.org/10.1016/j.jinsphys.2010.01.003
Autor:
Roger L. Miesfeld
Publikováno v:
Open Access Insect Physiology. 1:1-12
Guoli Zhou, Roger MiesfeldDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USAAbstract: Amino acids in the mosquito blood meal have two forms, protein-bound and plasma-free amino acids. To determine if the metabolic fate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f57cc8cfb8cc74ddd98055d23d78fa
https://doi.org/10.2147/oaip.s7160
https://doi.org/10.2147/oaip.s7160
Autor:
Guoli Zhou, Roger L. Miesfeld
Publikováno v:
Journal of Insect Physiology. 55:40-46
Diapause in overwintering adult female Culex pipiens mosquitoes plays an important role in the transmission of West Nile and other encephalitis-inducing flaviviruses. To investigate the dynamic metabolic processes that control Cx. pipiens diapause, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf84f5b4fa6e8be500476641235cd485
https://doi.org/10.1016/j.jinsphys.2008.10.002
https://doi.org/10.1016/j.jinsphys.2008.10.002