Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Roger K Prichard"'
Autor:
Jürgen Krücken, Lindy Holden-Dye, Jennifer Keiser, Roger K Prichard, Simon Townson, Benjamin L Makepeace, Marc P Hübner, Steffen R Hahnel, Ivan Scandale, Achim Harder, Daniel Kulke
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009682 (2021)
Current mass drug administration (MDA) programs for the treatment of human river blindness (onchocerciasis) caused by the filarial worm Onchocerca volvulus rely on ivermectin, an anthelmintic originally developed for animal health. These treatments a
Externí odkaz:
https://doaj.org/article/869be43936bd408ea70f27f4bdab6d28
Autor:
Stephen R Doyle, Catherine Bourguinat, Hugues C Nana-Djeunga, Jonas A Kengne-Ouafo, Sébastien D S Pion, Jean Bopda, Joseph Kamgno, Samuel Wanji, Hua Che, Annette C Kuesel, Martin Walker, Maria-Gloria Basáñez, Daniel A Boakye, Mike Y Osei-Atweneboana, Michel Boussinesq, Roger K Prichard, Warwick N Grant
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 7, p e0005816 (2017)
Treatment of onchocerciasis using mass ivermectin administration has reduced morbidity and transmission throughout Africa and Central/South America. Mass drug administration is likely to exert selection pressure on parasites, and phenotypic and genet
Externí odkaz:
https://doaj.org/article/29ebf34f18e0445a93f1f6c17f5f5173
Autor:
Hugues C Nana-Djeunga, Catherine Bourguinat, Sébastien D Pion, Jean Bopda, Jonas A Kengne-Ouafo, Flobert Njiokou, Roger K Prichard, Samuel Wanji, Joseph Kamgno, Michel Boussinesq
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 4, p e2824 (2014)
For two decades, onchocerciasis control has been based on mass treatment with ivermectin (IVM), repeated annually or six-monthly. This drug kills Onchocerca volvulus microfilariae (mf) present in the skin and the eyes (microfilaricidal effect) and pr
Externí odkaz:
https://doaj.org/article/71b272d7264a4145a5a2afc29957f1c9
Autor:
Hugo C Turner, Thomas S Churcher, Martin Walker, Mike Y Osei-Atweneboana, Roger K Prichard, María-Gloria Basáñez
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 4, p e2169 (2013)
BackgroundRecent studies in Mali, Nigeria, and Senegal have indicated that annual (or biannual) ivermectin distribution may lead to local elimination of human onchocerciasis in certain African foci. Modelling-based projections have been used to estim
Externí odkaz:
https://doaj.org/article/3071b230cfcd4e00a4ebffa8a627303a
Autor:
Aïssatou Diawara, Carli M Halpenny, Thomas S Churcher, Charles Mwandawiro, Jimmy Kihara, Ray M Kaplan, Thomas G Streit, Youssef Idaghdour, Marilyn E Scott, Maria-Gloria Basáñez, Roger K Prichard
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 5, p e2247 (2013)
Albendazole (ABZ), a benzimidazole (BZ) anthelmintic (AH), is commonly used for treatment of soil-transmitted helminths (STHs). Its regular use increases the possibility that BZ resistance may develop, which, in veterinary nematodes is caused by sing
Externí odkaz:
https://doaj.org/article/43e7a7a448644c4fa2b6661568863b99
Autor:
Sébastien D S Pion, Hugues C Nana-Djeunga, Joseph Kamgno, Nicholas Tendongfor, Samuel Wanji, Flobert Njiokou, Roger K Prichard, Michel Boussinesq
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 2, p e2084 (2013)
BACKGROUND/OBJECTIVE: Ivermectin has been the keystone of onchocerciasis control for the last 25 years. Sub-optimal responses to the drug have been reported in Ghanaian communities under long-term treatment. We assessed, in two Cameroonian foci, whet
Externí odkaz:
https://doaj.org/article/8b58a62a73e543f58d42ee0560679813
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 23, Iss , Pp 10-18 (2023)
Prevention of canine heartworm disease, caused by Dirofilaria immitis, relies on macrocyclic lactones for which drug resistance is now a concern. Although genetic polymorphisms have been associated with resistance in D. immitis populations, the mecha
Externí odkaz:
https://doaj.org/article/d352619c215245b7a55514d553ffb6e7
Autor:
James S McCarthy, Sara Lustigman, Guo-Jing Yang, Rashida M Barakat, Héctor H García, Banchob Sripa, Arve Lee Willingham, Roger K Prichard, María-Gloria Basáñez
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 4, p e1601 (2012)
Diagnostic tools appropriate for undertaking interventions to control helminth infections are key to their success. Many diagnostic tests for helminth infection have unsatisfactory performance characteristics and are not well suited for use in the pa
Externí odkaz:
https://doaj.org/article/821f340f43be4cc1b33bd20a38e74915
Autor:
Sara Lustigman, Roger K Prichard, Andrea Gazzinelli, Warwick N Grant, Boakye A Boatin, James S McCarthy, María-Gloria Basáñez
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 4, p e1582 (2012)
A disproportionate burden of helminthiases in human populations occurs in marginalised, low-income, and resource-constrained regions of the world, with over 1 billion people in developing areas of sub-Saharan Africa, Asia, and the Americas infected w
Externí odkaz:
https://doaj.org/article/28968a02669c499caf20fa77771c6690
Autor:
María-Gloria Basáñez, James S McCarthy, Michael D French, Guo-Jing Yang, Martin Walker, Manoj Gambhir, Roger K Prichard, Thomas S Churcher
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 4, p e1548 (2012)
Mathematical modelling of helminth infections has the potential to inform policy and guide research for the control and elimination of human helminthiases. However, this potential, unlike in other parasitic and infectious diseases, has yet to be real
Externí odkaz:
https://doaj.org/article/60586ea4433a4898a460e7663fc698a2