Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Roger K, Sandwick"'
Autor:
Nathaniel D Durfee, Nathaniel J. Henning, Sydney O. Shuster, Staci A. Hill, David R Stillman, Gregory Joon Kee Bowe, Sunhee Choi, Sebastian M. Fica-Contreras, Geoffrey D Vrla, Roger K. Sandwick, Kelly M Suralik
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 22:1211-1222
Extensive research has linked the amyloid-beta (Aβ) peptide to neurological dysfunction in Alzheimer's disease (AD). Insoluble Aβ plaques in the AD patient brain contain high concentrations of advanced glycation end-products (AGEs) as well as trans
Autor:
Sebastian M, Fica-Contreras, Sydney O, Shuster, Nathaniel D, Durfee, Gregory J K, Bowe, Nathaniel J, Henning, Staci A, Hill, Geoffrey D, Vrla, David R, Stillman, Kelly M, Suralik, Roger K, Sandwick, Sunhee, Choi
Publikováno v:
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 22(8)
Extensive research has linked the amyloid-beta (Aβ) peptide to neurological dysfunction in Alzheimer's disease (AD). Insoluble Aβ plaques in the AD patient brain contain high concentrations of advanced glycation end-products (AGEs) as well as trans
Autor:
Kathy Jewett, Roger K. Sandwick
Publikováno v:
Journal of Chemical Education. 88:1170-1174
The enzyme ribose 5-phosphate isomerase (RpiA) has many features that make it attractive as a focal point of a semester-long, advanced biochemistry laboratory for undergraduate students. The protein can easily and inexpensively be isolated from spina
Publikováno v:
Biochemical and Biophysical Research Communications. 407:191-196
Glycation of horse heart metmyoglobin with d-ribose 5-phosphate (R5P), d-2-deoxyribose 5-phosphate (dR5P), and d-ribose with inorganic phosphate at 37°C generates an altered protein (Myo-X) with increased SDS-PAGE mobility. The novel protein product
Publikováno v:
Carbohydrate Research. 345:2499-2506
Ribose 5-phosphate (R5P) is a sugar known to undergo the Maillard reaction (glycation) at a rapid rate. In a reaction with the lysines of bovine heart cytochrome c, R5P generates superoxide (O2-) that subsequently reduces ferri-cytochrome c to ferro-
Autor:
Elizabeth Breuer, Andrew W. Harris, Ryan Gamble, Steven K. O’Banion, Roger K. Sandwick, Admire Munanairi
Publikováno v:
Carbohydrate Research. 342:2575-2592
Ribose 5-phosphate (R5P) undergoes the Maillard reaction with amines at significantly higher rates than most other sugars and sugar phosphates. The presence of an intramolecular phosphate group, which catalyzes the early stages of the Maillard reacti
Publikováno v:
Journal of Inorganic Biochemistry. 81:73-80
The decomposition of 5-phosphoribosyl-α-1-pyrophosphate (PRPP) in the presence of Mg 2+ at pH=7.8 yields a combination of products including ribose 5-phosphate, ribose 1-phosphate, 5-phosphoribosyl 1,2 cyclic phosphate, inorganic phosphate, and pyro
Autor:
Roger K. Sandwick, Michael C. Downey, Rebecca A. Gersten, Lisa M. Gretebeck, Gordon J. Hildick-Smith
Publikováno v:
Biochemistry. 50(51)
Spontaneous glycation of bovine heart cytochrome c (cyt c) by the sugar ribose 5-phosphate (R5P) weakens the ability of the heme protein to transfer electrons in the respiratory pathway and to bind to membranes. Trypsin fragmentation studies suggest
Publikováno v:
Analytical Biochemistry. 203:47-52
A pair of ribonuclease assays have been developed which offer improvements in specificity, simplicity, and/or sensitivity over current procedures. The assays measure the rate of adenosine release upon ribonuclease hydrolysis of 3′-adenosyl dinucleo
Autor:
Gulnar Rawji, Roger K. Sandwick, Sunhee Choi, Kurt B. Schaberg, Michelle L. Personick, Benjamin J. Fowler, Livia Vastag, Yuri C. Larrabee
Publikováno v:
Inorganic chemistry. 47(4)
Guanosine derivatives with a nucleophilic group at the 5' position (G-5') are oxidized by the Pt (IV) complex Pt( d, l)(1,2-(NH 2) 2C 6H 10)Cl 4 ([Pt (IV)(dach)Cl 4]). The overall redox reaction is autocatalytic, consisting of the Pt (II)-catalyzed P