Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Roger Jeffs"'
Autor:
Olivier Sitbon, Marc Humbert, Gillian Davis, Roger Jeffs, Nazzareno Galiè, David Zaccardelli, Alessandra Manes, Louis de Paillette, Gérald Simonneau, Luissa Presotto, Xavier Jaïs, Massimiliano Pallazini
Publikováno v:
Journal of Cardiovascular Pharmacology. 49:1-5
Intravenous epoprostenol improves exercise capacity and survival in patients with pulmonary arterial hypertension (PAH); however, chemical instability and a short half-life have caused limitations in its use. The chemically stable prostacyclin analog
Autor:
Kalpalatha K. Guntupalli, David Watson, Roger Jeffs, Ziad Hussein, Bernadette Jordan, David Zaccardelli, Gene Colice, Robert Grover, Jill Donaldson, Misba Beerahee, Jean Louis Vincent
Publikováno v:
Clinical Pharmacology & Therapeutics. 65:1-9
Objectives To characterize the pharmacokinetics of L-NG-methylarginine in patients with septic shock. Methods This was an international, uncontrolled, open-label study of L-NG-methylarginine (546C88) therapy given to 32 patients with septic shock. It
Long-term outcome in pulmonary arterial hypertension patients treated with subcutaneous treprostinil
Autor:
Robert Naeije, Nazzareno Galiè, Lewis J. Rubin, Carl Arneson, Roger Jeffs, Gérald Simonneau, Robyn J. Barst
Publikováno v:
The European respiratory journal. 28(6)
Pulmonary arterial hypertension (PAH) is fatal if untreated. Intravenous epoprostenol improves exercise capacity and haemodynamics in PAH, and increases survival in idiopathic PAH (IPAH). To evaluate the effects of subcutaneous (SC) treprostinil, a l
Autor:
Emile R, Mohler, William R, Hiatt, Jeffrey W, Olin, Michael, Wade, Roger, Jeffs, Alan T, Hirsch
Publikováno v:
Journal of the American College of Cardiology. 41(10)
In the current study, we hypothesized that beraprost would: 1) improve treadmill exercise performance and quality of life; and 2) decrease rates of ischemic events in patients with intermittent claudication.Previous trials with beraprost sodium, an o
Autor:
Roger Jeffs, Michael D. McGoon, Carl Arneson, Richard N. Channick, Jeff Sigman, Shelley Shapiro, Ronald J. Oudiz, Victor F. Tapson, Stuart Rich, Robin Flinchbaugh, Karlman Wasserman, Ivan M. Robbins, Vallerie V. McLaughlin, David Badcsch, Robyn J. Barst, Barry K. Rayburn, Lewis J. Rubin
Publikováno v:
Journal of the American College of Cardiology. 42:591
Autor:
Robyn J, Barst, Michael, McGoon, Vallerie, McLaughlin, Victor, Tapson, Stuart, Rich, Lewis, Rubin, Karlman, Wasserman, Ronald, Oudiz, Shelley, Shapiro, Ivan M, Robbins, Richard, Channick, David, Badesch, Barry K, Rayburn, Robin, Flinchbaugh, Jeff, Sigman, Carl, Arneson, Roger, Jeffs
Publikováno v:
Journal of the American College of Cardiology. (12):2119-2125
ObjectivesThe purpose of this study was to assess the safety and efficacy of the oral prostacyclin analogue beraprost sodium during a 12-month double-blind, randomized, placebo-controlled trial in patients with pulmonary arterial hypertension (PAH).B