Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Roger Janz"'
Autor:
Ariana R Andrei, Samantha Debes, Mircea Chelaru, Xiaoqin Liu, Elsa Rodarte, John L Spudich, Roger Janz, Valentin Dragoi
Publikováno v:
eLife, Vol 10 (2021)
Cortical inactivation represents a key causal manipulation allowing the study of cortical circuits and their impact on behavior. A key assumption in inactivation studies is that the neurons in the target area become silent while the surrounding corti
Externí odkaz:
https://doaj.org/article/e181f1fee54c4be49d02779e63fda9c5
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Primary visual cortical neurons exhibit diverse responses to visual stimuli yet how these signals are integrated during visual perception is not well understood. Here, the authors show that optogenetic stimulation of neurons situated near the visuall
Externí odkaz:
https://doaj.org/article/0abefcb4af954803a1dd44932d5e2221
Autor:
Joseph R. Campbell, Hongyan Li, Yanzhao Wang, Maxim Kozhemyakin, Albert J. Hunt, Xiaoqin Liu, Roger Janz, Ruth Heidelberger
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Neurotransmitter release at retinal ribbon-style synapses utilizes a specialized t-SNARE protein called syntaxin3B (STX3B). In contrast to other syntaxins, STX3 proteins can be phosphorylated in vitro at T14 by Ca2+/calmodulin-dependent protein kinas
Externí odkaz:
https://doaj.org/article/246ba9360ac942518dacb619895e8280
Autor:
Andreas R. Janecke, Lukas A. Huber, Roberto Adachi, Valeria Strauß, Anuradha Ganesh, Siham Al Sinani, Martha P. Schatz, Roger Janz, Badr AlSaleem, Martin Walter Laass, Majid Alfadhel, Sumanth Punuru, Elizabeth Sanchez, Xiaoqin Liu, Naveen Mittal, Fowzan S. Alkuraya, Ujwala S. Saboo, Rüdiger Adam, Sana Al Zuhaibi, Klaus Rohrschneider, Fathiya Al Murshedi, Thomas Müller, Ruth Heidelberger, Johanna C. Escher, Arne Viestenz
Publikováno v:
Human Genetics, 140(8), 1143-1156. Springer-Verlag
Human Genetics
Human Genetics
Biallelic STX3 variants were previously reported in five individuals with the severe congenital enteropathy, microvillus inclusion disease (MVID). Here, we provide a significant extension of the phenotypic spectrum caused by STX3 variants. We report
Autor:
Xiaoqin Liu, Samantha Debes, Valentin Dragoi, Roger Janz, John L. Spudich, Ariana R. Andrei, Mircea I. Chelaru, Elsa M. Rodarte
Publikováno v:
eLife, Vol 10 (2021)
Cortical inactivation represents a key causal manipulation allowing the study of cortical circuits and their impact on behavior. A key assumption in inactivation studies is that the neurons in the target area become silent while the surrounding corti
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
Visual stimuli evoke heterogeneous responses across nearby neural populations. These signals must be locally integrated to contribute to perception, but the principles underlying this process are unknown. Here, we exploit the systematic organization
Autor:
null Jacob D. Bhoi, null Zhijing Zhang, null Roger Janz, null Yanan You, null Haichao Wei, null Jiaqian Wu, null Christophe P. Ribelayga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0651f05d1d7772611e030211656d7f59
https://doi.org/10.1002/cne.25004/v3/response1
https://doi.org/10.1002/cne.25004/v3/response1
Publikováno v:
Biophysical Journal. 113:2281-2298
Neurons that form ribbon-style synapses are specialized for continuous exocytosis. To this end, their synaptic terminals contain numerous synaptic vesicles, some of which are ribbon associated, that have difference susceptibilities for undergoing Ca