Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Roger Hollis"'
Autor:
Kelly-Anne Masterman, Carina Walpole, Jonathon Cebon, Christopher Schmidt, Nikita Rosendahl, Ghazal Daraj, Irina Caminschi, Oscar Haigh, Kirsteen Tullett, Ingrid Leal-Rojas, Frances Pearson, Liam O’Brien, Eric Gschweng, Roger Hollis, Donald Kohn, Mireille Lahoud, Kristen Radford
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/d4758c67ff904546b9b8d3bff5789d7f
Autor:
Jennifer Bell, Kevin Collon, Cory Mayfield, Matthew Gallo, Stephanie Chang, Osamu Sugiyama, Amy Tang, Roger Hollis, Shefali Chopra, Donald Kohn, Jay Lieberman
Ex-vivo gene therapy has been shown to be an effective method for treating bone defects in preclinical models. As gene therapy is explored as a potential treatment option in humans, an assessment of the safety profile becomes an important next step.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fae1a0e86d71421c3edc24cff63dcaf0
https://doi.org/10.21203/rs.3.rs-2653748/v1
https://doi.org/10.21203/rs.3.rs-2653748/v1
Autor:
Kevin Collon, Jennifer A. Bell, Matthew C. Gallo, Stephanie W. Chang, Sofia Bougioukli, Osamu Sugiyama, Jade Tassey, Roger Hollis, Nathanael Heckmann, Daniel A. Oakes, Donald B. Longjohn, Denis Evseenko, Donald B. Kohn, Jay R. Lieberman
Publikováno v:
Gene Ther
Gene therapy, vol 30, iss 3-4
Gene therapy, vol 30, iss 3-4
Human adipose-derived mesenchymal stem cells (ASCs) transduced with a lentiviral vector system to express bone morphogenetic protein 2 (LV-BMP-2) have been shown to reliably heal bone defects in animal models. However, the influence of donor characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef761a832a7a813ed3dca8cc3ad7efae
https://pubmed.ncbi.nlm.nih.gov/36216880
https://pubmed.ncbi.nlm.nih.gov/36216880
Autor:
Chintan Parekh, Arineh Sahaghian, William Kim, Jessica Scholes, Shundi Ge, Yuhua Zhu, Shahab Asgharzadeh, Roger Hollis, Donald Kohn, Lingyun Ji, Jemily Malvar, Xiaoyan Wang, Gay Crooks
Publikováno v:
Stem cells (Dayton, Ohio). 30(4)
The cytokine thrombopoietin (Tpo) plays a critical role in hematopoiesis by binding to the extracellular domain and inducing homodimerization of the intracellular signaling domain of its receptor, c-Mpl. Mpl homodimerization can also be accomplished
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1e1dbf6de6eaccb0895cb3a45cd311
https://pubmed.ncbi.nlm.nih.gov/22290824
https://pubmed.ncbi.nlm.nih.gov/22290824
Autor:
Hisham Abdel-Azim, Yuhua Zhu, Roger Hollis, Xiuli Wang, Shundi Ge, Qian-Lin Hao, Goar Smbatyan, Donald B. Kohn, Michael Rosol, Gay M. Crooks
Publikováno v:
Blood. 111(8)
Self-renewal capacity is rapidly lost during differentiation of hematopoietic stem cells to lineage-committed progenitors. We demonstrate here that regulated intracellular signaling through the cytokine receptor Mpl induces profound expansion of not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d1041b487fba85985d86cbd647fefd
https://pubmed.ncbi.nlm.nih.gov/18434969
https://pubmed.ncbi.nlm.nih.gov/18434969
Autor:
Gay Crooks, Donald Kohn, Lora Barsky, Qian-Lin Hao, Xuili Wang, Roger Hollis, Yuhua Zhu, Hisham Abdel-Azim
Publikováno v:
Blood. 106:31-31
There are multiple applications for expansion of Hematopoietic Stem Cells (HSC) and progenitors in transplantation. Gene therapy for most hematopoietic diseases requires selective expansion of genetically corrected HSC to achieve therapeutic effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e99ae0c5ff8c8b964f683b5ea90f5bf
https://doi.org/10.1182/blood.v106.11.31.31
https://doi.org/10.1182/blood.v106.11.31.31