Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Roger Graham Hall"'
Autor:
Mark Montgomery, Jilali Kessabi, Manjunath B. Channapur, Ashok S. Shyadligeri, Roger Graham Hall
Publikováno v:
Synlett. 30:1057-1060
A synthesis of 6-chloro-5-(trifluoroacetyl)pyridine-3-carbonitrile, a versatile building block for the synthesis of trifluoromethylated N-heterocycles, is described. The reactions of 6-chloro-5-(trifluoroacetyl)pyridine-3-carbonitrile with 1,2- and 1
Autor:
Andrew Edmunds, Daniel Emery, Adam Burriss, Jürgen Harry Schaetzer, Roger Graham Hall, Olivier Jacob
Publikováno v:
Pest Management Science. 74:1228-1238
The pyridine ring, substituted by a trifluoromethyl substituent has been successfully incorporated into molecules with useful biological properties. During the period 1990 to September 2017, 14 crop protection products bearing a trifluoromethyl pyrid
Publikováno v:
Heterocyclic Communications. 23:415-419
Trifluoromethyl containing heterocycles are an integral part of many biologically active compounds in the agro and pharmaceutical chemistry. Herein, we report an efficient and concise three-step synthesis of 5-halo-6-trifluoromethylpyridine-3-carboni
Autor:
Clarence Rodrigues, Sitaram Pal, Roger Graham Hall, Long Lu, Xiuhua Yang, Yong Xiang, Bhanu N. Manjunath, Mark Montgomery
A simple, and efficient synthesis of 2,2-difluoro-3H-benzothiophen-3-ol using readily available sodium chlorodifluoroacetate (SCDA) is reported. We also explore new chemistry of these difluoro compounds. The salient feature of this approach includes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565aaf3771903a1489fdc5c2e8fafef9
An Efficient Synthesis of 1,3-Benzothiadiazin-4(3H)-one 2-Oxides: Novel Anthranilic Acid Derivatives
Publikováno v:
Synthesis. 48:3743-3752
Derivatives of anthranilic acid exhibit a range of useful biological activities. Herein we describe an efficient synthetic route to 1,3-benzothiadiazin-4(3H)-one 2-oxides via copper-catalyzed N-arylation of sulfonimidamides followed by cyclization. S
Autor:
Andrew Edmunds, Dave Hughes, Anna Cristina Dutton, Olivier Loiseleur, André Stoller, Jean Wenger, Roger Graham Hall, Stephan Trah, Jagadish Pabba, Andrew J. Crossthwaite, André Jeanguenat, Patricia Durieux
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:403-427
The diamide insecticides act on the ryanodine receptor (RyR). The synthesis of various bicyclic anthranilic derivatives is reported. Their activity against the insect ryanodine receptor (RyR) and their insecticidal activity in the greenhouse is prese
Publikováno v:
Synthesis. 47:3711-3716
Concise and efficient syntheses of nataxazole and AJI9561 have been accomplished. We also demonstrate a convenient route to obtain the related natural product UK-1. The key step involves C–H activation of a benzoxazole in the presence of ortho -iod
Publikováno v:
Tetrahedron Letters. 56:1374-1377
Using CuI/xantphos/Pd(OAc)2 catalytic system, the intermolecular C–C cross coupling between benzoxazoles and ortho-haloanilides has been developed in moderate to good yields. The procedure tolerates a series of functional groups on benzoxazole, suc
Publikováno v:
Synthesis. 45:3018-3028
A general synthetic route to six-membered cyclic N-aryl- and N-alkyl-substituted sulfonimidamides via an intramolecular ring closure of suitably functionalised acyclic sulfonimidamides is described. The structure of this new ring system was confirmed
Publikováno v:
ChemInform. 47
A concise first access to nataxazole (IVa) and AJI9561 (IVb) is elaborated which is also applicable to a new preparation of the natural product UK-1 (IVc).